山东大学耳鼻喉眼学报 ›› 2013, Vol. 27 ›› Issue (6): 82-84.doi: 10.6040/j.issn.1673-3770.0.2013.239

• 论著 • 上一篇    下一篇

角膜内皮炎药物治疗后内皮细胞的观察

陈凯1,张玉光2,韩旭光2,徐湘辉2,丁刚2   

  1. 1.莱芜钢铁集团有限公司医院眼科, 山东 莱芜 271100; 2.济南市第二人民医院眼科, 济南 250001
  • 收稿日期:2013-08-14 发布日期:2013-12-16
  • 通讯作者: 韩旭光。 Email:guanghui76@sohu.com
  • 作者简介:陈凯。 Email:593183562@qq.com

Observation of the endothelial cells of corneal endotheliitis after treatment

CHEN Kai1, ZHANG Yu-guang2, HAN Xu-guang2, XU Xiang-hui2, DING Gang2   

  1. 1. Department of Ophthalmology, Laiwu Steel Group Hospital, Laiwu 271100, Shandong, China; 2. Department of Ophthalmology, Jinan Second People′s Hospital, Jinan 250001, China
  • Received:2013-08-14 Published:2013-12-16

摘要:

目的    探讨角膜内皮炎对角膜内皮细胞数量和形态的影响。方法    选择角膜内皮炎患者20例(20眼),其中盘状型13例,弥漫型7例。入院后常规给予抗病毒药物及皮质类固醇激素眼水。应用角膜内皮镜于治愈后4~6周观察角膜内皮细胞的密度、六边形细胞的比例及变异系数的变化,并以健眼为对照组。结果    治疗组角膜内皮细胞的密度较对照组明显降低,六边形细胞所占的比例降低,而变异系数增加;弥漫型内皮炎组与盘状型内皮炎组比较,细胞密度降低,六边形细胞所占的比例降低,变异系数增加。结论    角膜内皮炎对角膜内皮细胞造成损害,导致明显的内皮细胞数量和形态改变,不同分型之间存在区别。

关键词: 治疗, 角膜内皮镜, 角膜内皮炎

Abstract:

Objective    To investigate the effect of corneal endotheliitis on the number and morphology of corneal endothelial cells. Methods    The study group included 20 cases (20eyes), including 13 cases of disciform endotheliitis and 7 cases of diffuse endotheliitis. All patients accepted systemic and topical antiviral medications combined with corticosteroids. The endothelium cells checked by corneal endothelial microscope were analyzed for cell density, coefficient variation of cell size and hexgonality 4-6 weeks after the patients were cured. The healthy eyes were set as the control group. Results        Compared with the control group, the treatment group had lower corneal endothelial cell density and hexagonal cell ratio and higher variation coefficient. Compared with the disciform endotheliitis group, the diffuse endotheliitis group had lower corneal endothelial cell density and hexagonal cell ratio and higher variation coefficient. Conclusion    Corneal endotheliitis can damage the corneal endothelial cells, leading to significant changes in their number and morphology. There were distinctions between different types.

Key words: Corneal endotheliitis, Treatment, Corneal endothelial microscope

中图分类号: 

  • R772.21
[1] 王坛,武珂,李连庆,宫丽丽. 皮下免疫治疗注射后出现全身不良反应的伴发因素及处理[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 71-74.
[2] 吴静,刘业海. 头颈部鳞状细胞癌的靶向治疗研究进展[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 97-102.
[3] 沈勤峰,沈小燕,朱荣强,蒋斐斐,郎军添. 鼻内镜下中鼻甲功能性部分切除治疗慢性鼻窦炎76例分析[J]. 山东大学耳鼻喉眼学报, 2018, 32(5): 82-85.
[4] 代亚错,李靖,万保罗,臧艳姿,黄颖铭. 个体化治疗咽喉部海绵状血管瘤二例[J]. 山东大学耳鼻喉眼学报, 2018, 32(4): 110-112.
[5] 刘义平,林远超. 负压引流防治腮腺术后涎瘘112例[J]. 山东大学耳鼻喉眼学报, 2018, 32(4): 65-67.
[6] 陈鸣,俞雪飞. 浅谈伴有变应性鼻炎的慢性鼻窦炎的治疗[J]. 山东大学耳鼻喉眼学报, 2018, 32(3): 18-22.
[7] 张桂敏,林鹏. 慢性鼻-鼻窦炎的内在型:从基础到临床[J]. 山东大学耳鼻喉眼学报, 2018, 32(3): 14-17.
[8] 覃纲,梁灼萍. 变应性真菌性鼻-鼻窦炎免疫治疗现状[J]. 山东大学耳鼻喉眼学报, 2018, 32(3): 23-26.
[9] 吴湘萍. 患者管理方式对变应性鼻炎舌下含服粉尘螨滴剂疗效的影响[J]. 山东大学耳鼻喉眼学报, 2018, 32(3): 68-72.
[10] 王仙,李颖,赵博军. 息肉样脉络膜血管病变诊疗进展[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 103-106.
[11] 高进良,年婉清,李烁. 鼻内镜手术联合鼻用糖皮质激素治疗腺样体肥大性[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 38-42.
[12] 吕丹,李明霞,马兰枝,张馨元,肖浩,陈飞,刘均,李珍. 累及纵膈的头颈部丛状I型神经纤维瘤病两例[J]. 山东大学耳鼻喉眼学报, 2018, 32(1): 82-86.
[13] 陈红,曹慧玲,窦鑫,高下. 右侧鼻腔小细胞神经内分泌癌一例并文献复习[J]. 山东大学耳鼻喉眼学报, 2018, 32(1): 89-92.
[14] 孙滨,郭伯敏,康杰,邓先兆,伍波,樊友本. 甲状腺未分化癌的规范化治疗[J]. 山东大学耳鼻喉眼学报, 2017, 31(6): 16-20.
[15] 敬尚林. 儿童上气道咳嗽综合征临床诊疗现状[J]. 山东大学耳鼻喉眼学报, 2017, 31(6): 87-91.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!