耳后药物注射治疗突发性聋32例

doi:10.6040/j.issn.1673-3770.0.2014.070

摘要/Abstract

摘要： 目的观察耳后注射糖皮质激素治疗突发性聋的疗效.方法 65例突聋患者分为耳后注射组(32例)和鼓室给药组(33例),除常规治疗外,两组分别经耳后注射和鼓膜穿刺给予地塞米松0.5 mg,1次/3 d,疗程14 d.结果耳后注射组和鼓室给药组听力改善分别为(13.2±8.6)dB和(14.6±11.1)dB,两组治疗前后比较差异均有统计学意义(P<0.05),组间比较差异无统计学意义(P>0.05),不良反应试验组低于对照组(P<0.05).结论突聋患者耳后局部注射糖皮质激素效果明显、操作简单、不良反应低,可作为鼓室给药有禁忌时的备选疗法.

关键词: 突发性聋, 耳后注射, 地塞米松, 鼓膜注射

Abstract: Objective To evaluate the postaurical injection of corticosteroids to treat sudden hearing loss. Methods 65 patients with sudden hearing loss were divided into postaurical injection group (n=32) and intratympanic administration group (n=33). In addition to conventional medication, two groups were injected dexamethasone 0.5 mg through postaurical or intratympanic approaches on every three days in a 14-day course. Results The hearing improvement in postaurical injection group and intratympanic administration group were 13.2±8.6 dB and 14.6±11.1 dB. Compared to the pre-treatment, the differences were significant in both groups (P<0.05), however, no significant difference were noted between the groups (P>0.05). Adverse reactions occurred less in experimental group than the control (P<0.05). Conclusion Postaurical injection is effective, simple and safe to treat sudden hearing loss, which can serve as an alternative for intratympanic administration.

Key words: Sudden hearing loss, Postaurical injection, Intratympanic injection, Dexamethasone

中图分类号:

R764.43

江朝勇, 蔡永明, 殷亚磊. 耳后药物注射治疗突发性聋32例[J]. 山东大学耳鼻喉眼学报, 2014, 28(6): 18-20.

JIANG Chao-yong, CAI Yong-ming, YIN Ya-lei. Clinical trial of postaurical drug injection to treat sudden hearing loss[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(6): 18-20.

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