关键词: 喉重建, 动物实验, 镍钛合金支架, 双蒂带状肌筋膜瓣

Abstract: Objective To explore the outcome of repairing a laryngeal stent and unilateral large-scale tissue defect with a nickel-titanium alloy stent and double-strap ribbon myofascial flap in beagle dogs. Methods Ten beagle dogs were used. One-half of the right thyroid cartilage plate and corresponding acoustic chamber tissue were removed. A nickel-titanium alloy stent was fixed to the right thyroid cartilage plate stump. The right pedicle ribbon myofascial flap was placed into the throat cavity and sutured to the acoustic chamber tissue and thyroid cartilage stump, completely wrapping the stent. After the operation, the wounds on the laryngeal surface and healing of the nickel-titanium alloy stent into the surrounding tissue were regularly observed. Results Of the 10 experimental dogs, 1 died of extensive subcutaneous and mediastinal emphysema. Nine dogs recovered well without breathing difficulties. At 1, 7, and 14 months after the operation, there was a small amount of granulation in the larynx wound, which disappeared in March and June; subsequently, the wound surface in the laryngeal cavity was smooth. Conclusion Nickel-titanium alloy stents and double-strapped myofascial flaps can be used to repair and reconstruct a wide range of defects in canine laryngeal stents and tissues. When the surgical method is properly selected, superior results can be obtained.

Key words: Reconstruction of the larynx, Animal experiments, Nitinol stents, Double-pedicled fascial flap