山东大学耳鼻喉眼学报 ›› 2015, Vol. 29 ›› Issue (5): 65-68.doi: 10.6040/j.issn.1673-3770.0.2015.148

• 论著 • 上一篇    下一篇

荧光素眼底血管造影联合同步吲哚青绿血管造影在高度近视性眼底病变观察的效果评估

朱子诚, 王小中, 柯根杰, 温跃春, 孙思勤   

  1. 安徽医科大学附属省立医院眼科, 安徽 合肥 230001
  • 收稿日期:2015-04-09 修回日期:2015-09-22 出版日期:2015-10-16 发布日期:2015-10-16
  • 作者简介:朱子诚,E-mail:zczhu123@163.com

Analysis of simultaneous indocyanine green angiography and fundus fluorescein angiography in high myopia

ZHU Zicheng, WANG Xiaozhong, KE Genjie, WEN Yuechun, SUN Siqin   

  1. Department of Ophthalmology, Anhui Provincial Hospital, Anhui Medical University, Hefei 230001, Anhui, China
  • Received:2015-04-09 Revised:2015-09-22 Online:2015-10-16 Published:2015-10-16

PDF (PC)

511

摘要： 目的 探讨荧光素眼底血管造影(FFA)联合同步吲哚青绿血管造影(ICGA)观察高度近视性眼底病变的效果。方法 对32例58眼高度近视眼患者分别进行眼底检查、眼底彩色照相、共焦激光造影系统(荧光素钠和吲哚青绿同步)血管造影,对比分析FFA和ICGA检查图像。结果 58眼中ICGA显示21眼有漆裂纹,而FFA显示仅15眼有明显的漆裂纹。ICGA显示11眼中有脉络膜新生血管(CNV),其中FFA仅显示8眼CNV。FFA和ICGA均显示23眼有多灶性脉络膜萎缩。结论 ICGA可更清楚地显示高度近视眼的脉络膜损害, FFA和ICGA同步检查能更全面地了解高度近视患者眼底视网膜与脉络膜的病理变化,有助于全面了解病情并指导进一步治疗。

关键词: 近视, 荧光素血管造影技术, 吲哚青绿, 眼底病变

Abstract: Objective To discuss the iconographic characteristics and clinical significance of synchronic examination of indocyanine green angiography (ICGA) and fundus fluorescein angiography (FFA) for high myopia. Methods Thirty-two patients (58 eyes) with high myopia (>-6.00 D), selected randomly and consecutively, underwent ocular examination, fundus color photography, ICGA and FFA synchronically. The findings for the two modes of angiographies were compared. Results ICGA showed lacquer cracks in 21 eyes, while FFA showed lacquer cracks in only 15 eyes. ICGA showed choroid neovascularization (CNV) in 11 eyes, while FFA showed CNV in only 8 eyes. FFA and ICGA evenly showed multifocal choroid atrophy in 23 eyes. Conclusion ICGA can give more exact information on the lesions of choroid in high myopia. The synchronic examination of ICGA and FFA may act as a guide to the therapy for high myopia.

Key words: Fundusfluorescein, Angiography, Myopia, Indocyaninegreen

中图分类号: 

  • R774
[1] Jankowska-lech I, Terelak B, Grabska-liberek I. Choroidal vasculopathy detected by indocyaninegreen angiography in diabetic patients[J]. Klin Oczna, 2007, 109(10-12):413-417.
[2] Ascaso F J, Rojo M, Minguez E, et al. Diagnostic and therapeutic challenges[J]. Retina, 2011, 31(3):616-22.
[3] Liu H H, Xu L, Wang Y X, et al. Prevalence and progression of myopic retinopathy in Chinese adults: the Beijing Eye Study[J]. Ophthalmology, 2010, 117(9):1763-1768.
[4] 张红,庄曾渊.高度近视患者的荧光素眼底血管造影与吲哚青绿血管造影对比分析[J].中国中医眼科杂志,2002,12(2):91-94. ZHANG Hong, ZHUANG Zengyuan. An analysis on findings of the fundus fluorescein angiography and indocyanine green angiography in the patients with high myopia[J]. J Trad Chin Ophthalmol, 2002, 12(2):91-94.
[5] 彭锡嘉,苏兰萍.高度近视后极部眼底自发荧光特征[J]. 中华实验眼科杂志,2013,31(3):258-260. PENG Xijia, SU Lanping. Fundus autofluorescence characteristics in high myopia[J]. Chin J Exp Ophthalmo, 2013, 31(3):258-260.
[6] Axer Siegel R, Cotler D, Priel E, et al. Indocyanine green angiography in high myopia[J]. Ophthalmic Surg Lasers Imaging, 2004, 35(2):139-145.
[7] 文峰,吴德正. 浅谈吲哚青绿血管造影的临床释义[J]. 中华眼底病杂志,2002,18(1):74-76. WEN Feng, WU Dezheng. Clinical meaning of fundus fluorescein angiography[J]. Chin J Ocul Fundus Dis, 2002, 18(1):74-76.
[8] Kim Y M, Yoon J U, Koh H J. The analysis of lacquer crack in the assessment of myopic choroidal neovascularization[J]. Eye, 2011, 25(7):937-46.
[9] Levy J H, Pollock H M, Curtin B J. The Fuchs' spot: an ophthalmoscopic and fluorescein angiographic study[J]. Ann Ophthalmol, 1977, 9(11):1433-1443.
[10] Ladaique M, Dirani A, Ambresin A. Long-term follow-up of choroidal neovascularization in pathological myopia treated with intravitreal ranibizumab[J]. Klin Monbl Augenheilkd, 2015, 232(4):542-547.
[11] Wong T Y, Ohno-Matsui K, Leveziel N, et al. Myopic choroidal neovascularisation: current concepts and update on clinical management[J]. Br J Ophthalmol, 2015, 99(3):289-296.
[12] Yannuzzi L A, Sorenson J A. Indocyanine green videoangiography: current status[J]. Eur Ophthalmol, 1994, 4(2):69-81.
[13] 牛伟, 刘娉,庄文娟.高度近视黄斑病变眼底荧光血管造影的表现[J]. 宁夏医学院学报,2008,30(6):763-764. NIU Wei, LIU Ping, ZHUANG Wenjuan. Analysis of fundus fluorescein angiography of high myopic maculopathy[J]. J Ningxia Med Coll, 2008, 30(6):763-764.
[1] 宋森,李莹,丁欣,金玉梅. 飞秒激光小切口基质透镜取出术后早期视力恢复的相关因素分析[J]. 山东大学耳鼻喉眼学报, 2018, 32(4): 77-79.
[2] 徐静静,郭海科. 有晶体眼后房型人工晶体植入与飞秒激光微小切口角膜基质透镜切除术矫正高度近视对眼表影响分析[J]. 山东大学耳鼻喉眼学报, 2017, 31(4): 18-20.
[3] 席玲,袁满红,过朵芳,杨华丽. LASIK患者眼压测量的多因素分析[J]. 山东大学耳鼻喉眼学报, 2017, 31(2): 99-103.
[4] 刘文静. TransPRK与LASEK对薄角膜近视眼术后视力、屈光度及角膜生物力学性能的影响[J]. 山东大学耳鼻喉眼学报, 2016, 30(6): 70-74.
[5] 朱子诚, 温跃春, 吴章友, 柯根杰. 高度近视合并白内障患者植入不同人工晶状体术后黄斑区视网膜厚度的变化[J]. 山东大学耳鼻喉眼学报, 2015, 29(1): 40-43.
[6] 戴丽华，张秀果，张京京，郭霞. 近用复合棱镜防治青少年近视的临床研究[J]. 山东大学耳鼻喉眼学报, 2014, 28(1): 73-75.
[7] 赵军，陈尧，秦建民. 青年人不同程度近视24°蓝黄视野检测结果的研究[J]. 山东大学耳鼻喉眼学报, 2013, 27(5): 59-61.
[8] 唐东永，谭少健，梁皓，何剑，李霞. Bigbag人工晶状体应用于高度近视白内障眼玻璃体后脱离的临床观察[J]. 山东大学耳鼻喉眼学报, 2013, 27(3): 50-53.
[9] 林琳1，王玉2，吴昌龙2，盛艳娟2. 激光治疗周边浅层孔源性视网膜脱离的临床观察[J]. 山东大学耳鼻喉眼学报, 2012, 26(3): 70-71.
[10] 方旺1，杨贤增2，张莉1，李雯霖1，钟晖1，陈凌燕1. 少年儿童近视的临床特点及相关环境因素研究[J]. 山东大学耳鼻喉眼学报, 2012, 26(3): 75-78.
[11] 赵静静1，杨学秋1，庄文娟2 . 定量检测LASIK手术对视网膜影响的研究进展[J]. 山东大学耳鼻喉眼学报, 2012, 26(3): 79-82.
[12] 刘雯. 近距离工作诱发暂时性近视对近视发展的影响[J]. 山东大学耳鼻喉眼学报, 2012, 26(3): 83-85.
[13] 查梅芳，陈志钧. 角膜塑形术治疗青少年近视中角膜上皮损伤调[J]. 山东大学耳鼻喉眼学报, 2011, 25(4): 90-92.
[14] 雷玉琳1，郑秀云1，党光福2，刘素美1. Pentacam、OrbscanⅡ和A超测量中央角膜厚度的分析[J]. 山东大学耳鼻喉眼学报, 2011, 25(2): 89-91.
[15] 朱子诚，柯根杰，潘红飙. 超声生物显微镜在青少年挫伤性近视发病机制的应用研究[J]. 山东大学耳鼻喉眼学报, 2010, 24(01): 54-.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
网站版权所有 © 2018 《山东大学耳鼻喉眼学报》编辑部　
地址：山东省济南市山大南路27号（250100）电话：+86-0531-88366912 E-mail: ebhxb@sdu.edu.cn
本系统由北京玛格泰克科技发展有限公司设计开发