山东大学耳鼻喉眼学报 ›› 2018, Vol. 32 ›› Issue (3): 91-95.doi: 10.6040/j.issn.1673-3770.0.2017.495
李上1,张薇1,卢红双2,臧云晓2,董宏伟1,郭纯刚1,潘志强2,接英2
LI Shang1, ZHANG Wei1, LU Hongshuang2, ZANG Yunxiao2, DONG Hongwei1, GUO Chungang1, PAN Zhiqiang2, JIE Ying2
摘要: 目的 评价热脉动系统LipiFlow对轻、中度睑板腺功能障碍(MGD)的患者治疗并随访6个月的临床效果。 方法 回顾性分析2016年3月至2016年11月在北京佑安医院眼科就诊,并进行LipiFlow治疗的15例(30眼)睑板腺功能障碍患者的临床资料。受试者分别在治疗前,治疗后3个月,治疗后6个月进行SPEED问卷,不完全眨眼比率(PB),脂质层厚度(LLT),泪膜破裂时间(TBUT),基础泪液分泌量(SIt)和睑板腺开口油脂分泌情况(MGYLS)。 结果 SPEED问卷评分在治疗后3个月和6个月时分别为10.20±3.57和9.87±3.68,与治疗前的12.13±2.42相比降低。PB比率在治疗后3个月和6个月时分别为60%和62.45%,与治疗前的72.24%相比下降。LLT在治疗前、治疗后3个月和治疗后6个月分别为(71.70±21.23)nm,(72.03±20.52)nm和(74.60±20.07)nm。TBUT在治疗前、治疗后3个月和治疗后6个月分别为(5.37±2.19)s,(6.33±2.34)s和(6.40±2.50)s。 SIt在治疗前、治疗后3个月和治疗后6个月分别为(5.30±4.41)mm,(5.93±4.51)mm和(7.43±7.26)mm。MGYLS在治疗前、治疗后3个月和治疗后6个月分别为3.50±2.11,4.23±1.99和3.83±1.97。LLT,TBUT,SIt和MGYLS三个时间点进行两两比较,无统计学差异。 结论 热脉动系统可以减轻轻、中度睑板腺功能障碍的主观症状,同时改善不完全眨眼的比率,可以巩固治疗效果长达6个月。
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