山东大学耳鼻喉眼学报 ›› 2022, Vol. 36 ›› Issue (2): 133-138.doi: 10.6040/j.issn.1673-3770.0.2021.078

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阻塞性睡眠呼吸暂停低通气综合征与血脂紊乱关系的研究进展

杨晰珺1,关建2，吴海莺1   

  1. 1. 昆明医科大学第二附属医院 耳鼻咽喉头颈外科, 云南 昆明 650101;
    2. 上海交通大学附属第六人民医院 耳鼻咽喉头颈外科, 上海 200233
  • 发布日期:2022-04-15
  • 通讯作者: 吴海莺. E-mail:smilewhy@126.com
  • 基金资助:
    云南省科技厅-昆明医科大学应用基础研究联合专项［2017FE467(-178)］;昆明医科大学2020年硕士研究生创新基金(2020S204)

Research progress on the relationship between obstructive sleep apnea-hypopnea syndrome and dyslipidemia

YANG Xijun1, GUAN Jian2,WU Haiying1   

  1. 1. Department of Otorhinolaryngology & Head and Neck Surgery, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, Yunnan, China;
    2. Department of Otorhinolaryngology & Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China
  • Published:2022-04-15

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171

摘要： 阻塞性睡眠呼吸暂停低通气综合征是常见的睡眠呼吸障碍疾病之一,与脂代谢紊乱均为影响人类健康的重要慢性疾病。两种疾病联系紧密,均与心脑血管疾病的发展密切相关,危害性极大,故受到广泛关注。就阻塞性睡眠呼吸暂停低通气综合征对血脂紊乱影响可能的病理生理机制和临床相关研究的最新进展进行综述。

关键词: 睡眠呼吸暂停低通气综合征, 血脂紊乱, 间歇缺氧, 睡眠片段化, 脂蛋白

Abstract: Obstructive sleep apnea-hypopnea syndrome(OSAHS)is a common sleep apnea disorder. Both OSAHS and lipid metabolism disorders are important chronic conditions affecting human health, and they are closely related to the development of cardiovascular and cerebrovascular diseases. This article will review the possible pathophysiological mechanisms underlying the effect of OSAHS on dyslipidemia and the progress of related clinical research.

Key words: Sleep apnea-hypopnea syndrome, Dyslipidemia, Intermittent hypoxia, Sleep fragmentation, Lipoproteins

中图分类号: 

  • R766.7
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