Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (1): 59-63.doi: 10.6040/j.issn.1673-3770.0.2021.439

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Clinical and survival analysis of primary squamous cell carcinoma of the thyroid 12 cases

LI Zhilin1, ZHENG Zhou2, AN Wei3   

  1. 1. Department of Head and Neck Oncology, Shanxi Province Cancer Hospital, Taiyuan 030013, Shanxi, China;
    2. Shanxi Medical University, Taiyuan 030001, Shanxi, China;
    3. Department of Oral and Maxillofacial Surgery, Shanxi Provincial People's Hospital, Taiyuan 030012, Shanxi, China
  • Published:2023-02-06

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Abstract: Objective This study aimed to investigate the clinical characteristics, survival analysis, and factors affecting the prognosis of primary squamous cell carcinoma of the thyroid(PSCCT). Methods The preoperative clinical manifestations, thyroid ultrasound features, surgical methods and postoperative pathology of 12 patients with PSCCT admitted to the Department of Head and Neck Surgery in the hospital from January 2012 to December 2019 were retrospectively analyzed, including the immunohistochemical results, comprehensive treatment methods and prognosis. The Kaplan-Meier method, Log-rank test and Cox proportional hazard regression model were used for survival analysis. Results Univariate analysis showed that combined papillary carcinoma was associated with the overall survival(OS)in patients with PSCCT. Multivariate analysis revealed that the absence of the papillary carcinoma was a risk factor for OS. Conclusion PSCCT is a rare malignant thyroid tumor with a high degree of malignancy, rapid development and poor prognosis. If diagnosing PSCCT clinically, it is necessary to determine whether it is associated with papillary carcinoma and selecting the appropriate treatment is the key to improve the survival rate.

Key words: Primary squamous cell carcinoma of the thyroid, Risk factor, Single-factor analysis, Multivariate analysis, Survival

CLC Number: 

  • R736.1
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