Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (2): 110-114.doi: 10.6040/j.issn.1673-3770.0.2019.530
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CHEN Huijun, SONG Shenghua, DONG Weida, ZHOU Han
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[1] 黄选兆, 汪吉宝, 孔维佳. 实用耳鼻咽喉头颈外科学[M]. 北京: 人民卫生出版社,2008:488. [2] Koodziejczyk J, Ponczek MB. The role of fibrinogen, fibrin and fibrin(ogen)degradation products(FDPs)in tumor progression[J]. Contemp Oncol(Pozn), 2013, 17(2): 113-119. doi:10.5114/wo.2013.34611. [3] Diao DM, Cheng Y, Song YC, et al. D-dimer is an essential accompaniment of circulating tumor cells in gastric cancer[J]. BMC Cancer, 2017, 17(1): 56. doi:10.1186/s12885-016-3043-1. [4] Yu XF, Hu FL, Yao Q, et al. Serum fibrinogen levels are positively correlated with advanced tumor stage and poor survival in patients with gastric cancer undergoing gastrectomy: a large cohort retrospective study[J]. BMC Cancer, 2016, 16: 480. doi:10.1186/s12885-016-2510-z. [5] Otten HM, Prins MH. Venous thromboembolism and occult malignancy[J]. Thromb Res, 2001, 102(6): V187-V194. doi:10.1016/s0049-3848(01)00235-3. [6] Zhu Y, Zhang LH, Zha HR, et al. Stroma-derived fibrinogen-like protein 2 activates cancer-associated fibroblasts to promote tumor growth in lung cancer[J]. Int J Biol Sci, 2017, 13(6): 804-814. doi:10.7150/ijbs.19398. [7] Liu YL, Lu Q, Liang JW, et al. High plasma fibrinogen is correlated with poor response to trastuzumab treatment in HER2 positive breast cancer[J]. Medicine(Baltimore), 2015, 94(5): e481. doi:10.1097/MD.0000000000000481. [8] 张礼, 燕锦. 血浆纤维蛋白原在结直肠癌中的研究进展[J]. 肿瘤预防与治疗, 2016, 29(4): 231-234. doi:10.3969/j.issn.1674-0904.2016.04.009. [9] 陈慧君, 宋圣花, 周涵, 等. 血小板与淋巴细胞比值对喉癌复发的预测价值[J]. 山东大学耳鼻喉眼学报, 2019, 33(3): 106-110. doi:10.6040/j.issn.1673-3770.1.2019.018. CHEN Huijun, SONG Shenghua, ZHOU Han, et al. Preoperative platelet-lymphocyte ratio is an independent prognostic factor for laryngeal squamous cell carcinoma[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 106-110. doi:10.6040/j.issn.1673-3770.1.2019.018. [10] Kucharczyk J, Sullivan C, Lu J, et al. Prognostic and Predictive Value of Pretreatment Derived Neutrophil-to-Lymphocyte Ratio in Non-Small-Cell Lung Cancer Patients Treated with an Immune Checkpoint Inhibitor[J]. J Cancer Ther, 2018, 9(1): 23-34. doi:10.4236/jct.2018.91004. [11] Lin Y, Liu Z, Qiu Y, et al. Clinical significance of plasma D-dimer and fibrinogen in digestive cancer: A systematic review and meta-analysis[J]. European journal of surgical oncology: the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2018,44(10):1494-1503. doi: 10.1016/j.ejso.2018.07.052. [12] Grafetstatter M, Husing A, Gonzalez Maldonado S, et al. Plasma Fibrinogen and sP-Selectin are Associated with the Risk of Lung Cancer in a Prospective Study[J]. Cancer epidemiology, biomarkers & prevention. 2019,28(7):1221-1227. doi:10.1158/1055-9965.EPI-18-1285. [13] Sahni A, Simpson-Haidaris PJ, Sahni SK, et al. Fibrinogen synthesized by cancer cells augments the proliferative effect of fibroblast growth factor-2(FGF-2)[J].J Thromb Haemost, 2008, 6(1): 176-183. doi:10.1111/j.1538-7836.2007.02808.x. |
[1] | LIU Yong, YUAN Cunli, CAO Hui, ZHENG Chengcai, CHAO Fang, XU Fenglei. CHD1L promotes proliferation, invasion and metastasis of laryngeal squamous cell carcinoma cells by EMT [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 32-39. |
[2] | CHENG Yao, ZHANG Zhen, YANG Ji, FENG Chengmin, DENG Qicheng, ZHANG Xi, ZHAO Rui, ZHU Xin, WU Junzhi, LIU Hai, DENG Shishan. Expression and clinical significance of CIP2A in hypopharyngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 40-44. |
[3] | LIU Pan, WANG Chuan, ZHAO Zeqi, WU Mei, XU Jifeng, LI Wei, ZHANG Weiqiang, LIU Wen. Five cases of metastatic clear cell carcinoma of the head and neck: a case report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(4): 45-50. |
[4] | WANG Zhongwei, YANG Lin, GUO Ya, SUN Bin, WANG Yali, MA Xiulong, REN Hongtao, BAO Xing. Analysis of the relationship between miR-429 and miR-200C expression and prognosis in patients with nasopharyngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(3): 81-86. |
[5] | WANG Yingying, ZHOU Han, DONG Weida, XING Guangqian, CHEN Zhibin, ZHANG Qingzhao, ZHANG Liqing. Analysis of distant metastasis and prognosis of adenoid cystic carcinoma of the external auditory canal [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 1-6. |
[6] | TAN Yufang, YI Tianhua. Clinical characteristics and prognosis of sudden sensorineural hearing loss in post-irradiated nasopharyngeal carcinoma survivors: a report of 18 cases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 35-39. |
[7] | FAN Yiyan, ZHANG Xiaolin, LIU Xiuzhen, YIN Jingjing, YUAN Jin, WANG Yanfei, CHEN Jun. Expression and clinical significance of CPS1 in laryngeal squamous cell carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(6): 72-76. |
[8] | This study aims to evaluate the level of expression of cyclin E2 in hypopharyngeal cancer and its relationship with clinical characteristics as well as prognosis. MethodsThe protein levels of cyclin E2 in tumor tissues and adjacent normal tissues were assessed by immunohistochemistry staining in 50 cases of hypopharyngeal cancer. The relationship between the expression level of cyclin E2 and clinical data was analyzed using the SPSS software. ResultsProtein levels of cyclin E2 in hypopharyngeal cancer were higher than protein levels of cyclin E2 in normal tissue(Z=-5.764,P=0.000). The cyclin E2 level in tumor tissue correlated with the tumor staging(Z=-1.995, P=0.046)and lymph node metastasis(Z=-2.176, P=0.030). The 5-year survival rates of patients with cyclin E2 positive and negative expression were 40.2% and 81.8%, respectively. Patients with high expression levels of cyclin E2 had a lower survival rate(χ=6.317, P=0.012). ConclusionThe abnormal expression of cyclin E2 protein in tumor tissues indicates that cyclin E2 may be involved in the development of hypopharyngeal cancer and could be a potential diagnostic and prognostic molecular marker.. Expression of cyclin E2 in hypopharyngeal cancer and its clinical significance [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 132-137. |
[9] | Rhinogenic headache is caused by rhinosinusitis or abnormal nasal anatomy. Currently, there are clear classifications and pain grading standards to diagnose the same. Further, its mechanism of action is now understood to involve trigeminal nerve stimulation and sensory neuropeptide substance P. Functional endoscopic surgery(FESS)is prioritized as a treatment modality. During surgery, it is imperative to restore the normal anatomy of the nasal cavity. Several clinical studies have reported that FESS was significantly effective in treating rhinogenic headache, with an overall effective rate of 90% and cure rate of 78%. Additionally, one report indicates that postoperative endoscopic examination and dressing change can effectively reduce the occurrence of complications and ensure safety of the treatment.. Dynamic analysis of rhinogenic headacheZHOU Fangming1, XIE Yan2, LIU Yang2 Overview JIANG Luyun2〓Guidance 1. Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, China 2. Department of Otorhinolaryngology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan, ChinaAbstract: [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(4): 130-133. |
[10] | XU Jinjing, HU Jinghua, WU Yuanqing, DENG Yi, YU Weiwei. Applications of CO2 laser microsurgery on laryngeal precancerous lesions and early glottic laryngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(3): 129-133. |
[11] | Yujing DING,Lan LAN,Qiuju WANG,Fei JI,Fen XIONG,Linyi XIE,Haina DING,Yin XIA,Hui ZHAO. Analysis of clinical characteristics and prognosis of post traumatic hearing loss [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(1): 9-14. |
[12] | ZONG Xiaofang, HU Guohua, ZHONG Shixun, LEI Yan, JIANG Lizhu, KANG Houyong. Analysis of the factors affecting the prognosis of low-frequency descending sudden hearing loss without vertigo [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(1): 33-37. |
[13] | CHEN Xuesong, FU Weiwei, LIU Jiangtao. The prognostic value of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in intensity modulated radiation therapy for nasopharyngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(1): 50-53. |
[14] | Yangfan LIU,Jian JIA,Baoluo WAN. A retrospective study on clinic manifestation and pathological of the larynx leukoplakia in 76 cases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(5): 162-165. |
[15] | Ruofei HUANG,Lixiao CHEN,Xinwei CHEN,Ziwei YU,Bin JIN,Jiangcai ZHU,Pin DONG. Recurrent laryngeal cancer [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 36-39. |
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