Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (2): 45-50.doi: 10.6040/j.issn.1673-3770.0.2022.043

• 论著 • Previous Articles    

Analysis of pulmonary function changes in patients with obstructive sleep apnea hypopnea syndrome

LI Zhuojun1,2, SONG Xicheng2, CHEN Xiumei2   

  1. 1. The 2nd Medical College of Binzhou Medical University, Yantai 264100, Shandong, China;
    2. Department of Otorhinolaryngology & Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University/Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai 264000, Shandong, China
  • Published:2023-03-30

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Abstract: Objective To investigate the relationship between pulmonary function and obesity in patients with obstructive sleep apnea-hypopnea syndrome(OSAHS). Methods A total of 169 cases of patients with and without OSAHS who were hospitalized in the Department of Otolaryngology & Head and Neck Surgery, Yuhuangding Hospital, Yantai from January 2015 to June 2021 were retrospectively analyzed. Analysis of pulmonary function and polysomnography(PSG)monitoring results and comparison of pulmonary function indicators of the non-OSAHS group and OSAHS group were conducted. The correlation between the pulmonary function indices and PSG results of patients with OSAHS was also identified. Results Apnea-hypopnea index(AHI)and body mass index(BMI)were positively correlated. Maximum vital capacity(Vcmax), forced vital capacity(FVCex), tidal volume(VT), inspiratory capacity(IC), and forced expiratory volume in one second(FEV1)were different between the severe and control groups. AHI was negatively correlated with VCmax, FVCex, PEF, FEV1, and IC. BMI was negatively correlated with VCmax, IC, and FVCex. Conclusion Patients with OSAHS had pulmonary function impairment, which was more apparent in severe patients. Obesity may be a factor leading to pulmonary function impairment in patients with OSAHS.

Key words: Obstructive sleep apnea-hypopnea syndrome, Pulmonary function, Obesity, Ventilatory dysfunction, Polysomnography

CLC Number: 

  • R766.7
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