Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2024, Vol. 38 ›› Issue (4): 149-153.doi: 10.6040/j.issn.1673-3770.0.2023.033

• Review • Previous Articles    

Advancements in non-surgical management of myopia and choroidal research

ZHANG Liyuan, ZHONG Dingjuan, WANG Hua   

  1. Department of Optometry and Ophthalmology, Hunan Provincial People's Hospital/The First Affiliated Hospital of Hunan Normal University, Changsha 410005, Hunan, China
  • Published:2024-07-09

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Abstract: The mechanisms of development of myopia are extremely complex. The “scleral hypoxia theory” proposed in recent years suggests that scleral hypoxia and remodeling may be a key factor in the development of myopia. Choroidal thickness and choroidal blood flow changes may play an important role in the retinal scleral pathway signaling and participate in the regulation of eyeball growth. Studies have shown choroidal thinning to be associated with the onset and development of myopia. Interventions such as orthokeratology, atropine eye drops and exposure to ambient light can increase choroidal thickness, suggesting that choroidal thickening is a protective factor for myopia progression. Therefore, this paper reviews the relationship between myopia and choroid, and the changes induced in the choroid by optical, drug and environmental interventions used for improvement of myopia, aiming to better understand the effects of such non-surgical interventions on choroid.

Key words: Myopia, Choroidal thickness, Choroidal blood flow, Intervention measure

CLC Number: 

  • R778.1+1
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