Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2024, Vol. 38 ›› Issue (3): 74-81.doi: 10.6040/j.issn.1673-3770.0.2023.177

• Original Article • Previous Articles    

Meta-analysis of the effect of red-light therapy on spherical equivalent, axial length, and choroidal thickness in myopic children

LI Yang, LIU Dong, CAO Wenjie   

  1. Department of Ophthalmology, Jiangding Distric Central Hospital Affiliated Shanghai University of Medicine & Health Science, Shanghai 201800, China
  • Published:2024-06-04

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Abstract: Objective To explore the effect of red-light therapy on equivalent sphere, axial length and choroidal thickness in myopic children. Methods We searched PubMed, Web of Science, Cochrane Library, Embase, CNKI, Wanfang, CBM, Vip, and Clinical trial registry on red-light therapy for myopia control published from the establishment of the database to October 28, 2022. The Cochrane Handbook was used for risk of bias and quality evaluation of the included literature, and Revman 5.3 software was used for Meta-analysis, and STATA 12.0 software was used to detect publication bias. Results A total of 1425 eyes from nine articles were included, of which five were randomized controlled trials and three were control studies. Meta-analysis showed that the inhibitory effect of red-light on the increase in spherical equivalent(SE)and axial length(AL)was better than that of the single-focus spectacles group(SE: WMD=0.41, 95%CI: 0.29-0.54, I2=65%, P<0.000 01; AL: WMD=-0.21, 95%CI: -026 - 0.15, I2=73%, P<0.000 01), the increase of choroidal thickness(CHT)in red-light therapy group was superior to that in single-focus spectacles group(WMD=26.05, 95%CI: 22.11-29.99, I2=45%, P<0.000 01). Conclusion The control effect of red-light therapy was better than that of the single-focus spectacles, but long-term use of adverse reations still need to be further observed.

Key words: Red-light therapy, Myopia, Axis length, Spherical equivalent, Choroidal thickness, Meta-analysis

CLC Number: 

  • R778.1
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