Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2024, Vol. 38 ›› Issue (2): 144-149.doi: 10.6040/j.issn.1673-3770.0.2022.042

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Application of optical tomography angiography and artificial intelligence in choroidal neovascularization secondary to pathologic myopia

WU Lili, QU Yi   

  1. Department of Geriatrics, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Online:2024-03-20 Published:2024-03-29

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Abstract: In recent years, the incidence of pathological myopia (PM) has increased. PM is a global eyeblinding problem and a heavy social burden. Choroidal neovascularization (CNV) is a severe complication of PM that can cause macular disorders. This may lead to central scotoma, metamorphopsia, visual field loss, and eventually blindness if left treated. Optical coherence tomography angiography (OCTA) provides an automatic and accurate visualization of the layers of the retina and choroid, which allows a qualitative and quantitative description of the microvascular areas of the retina and choroid. OCTA can be used to detect the pathogenesis of high myopia, at the microvascular level of the retina. OCTA helps diagnose CNV secondary to PM due to its ability to show the position and size of the CNV. As management, photodynamic and antivascular endothelial growth factor therapies have been used. OCTA can be used to evaluate the therapeutic effect of PMCNV. This article provides an overview of the current research options on the diagnosis and treatment of CNV and discusses the problems and prospects when they are combined with artificial intelligence for choroidal imaging, to provide reference for clinical work.

Key words: Pathological myopia, Choroidal neovascularization, Optical coherence tomography angiography, Artificial intelligence

CLC Number: 

  • R774.1
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