Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2025, Vol. 39 ›› Issue (5): 8-19.doi: 10.6040/j.issn.1673-3770.0.2023.440

• Original Article • Previous Articles    

Medication rule and diagnosis-treatment characteristics of Huang Ping in treatment of tinnitus: a study based on R language data mining

LING Wenchen, CHEN Jiaxu, XU Zhihui, ZHENG Wei, LIU Guangyu, ZHAO Xinyu, HUANG Ping   

  1. Department of Otolaryngology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
  • Published:2025-09-19

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Abstract: Objective To analyse the medication characteristics of the prescriptions for tinnitus issued by Professor Huang Ping and the characteristics of Professor Huang Ping's diagnosis and treatment of tinnitus by using R language data mining techniques. Methods The study was conducted on patients with tinnitus who visited Professor Ping Huang's outpatient clinic from January 2022 to September 2023. Clinical data and prescription drug information were collected. Microsoft Office Excel 2022 was used to create a database of Professor Ping Huang's Chinese medicine prescriptions. Descriptive analyses of the nature, flavour, meridian distribution and efficacy of the prescriptions were performed using R. The patterns of commonly used drug pairs were further mined using Apriori association rule analysis and hierarchical cluster analysis. Results A total of 225 prescriptions and 173 kinds of medications were screened. The top 10 most frequently used medication were Rhizoma Ligustici Chuanxiong, Poria, Radix Bupleuri, Radix Codonopsis, stir-frying Rhizoma Atractylodis Macrocephalae with bran, Glycyrrhizae, Rhizome Pinelliae Preparata, Stir-baked Spine Date Seed, Medicated Leaven, and Burnt Hawthorn Fruit. The nature of the medicine prescriptions are warm and mild, and the taste is mostly sweet, pungent, and bitter. The main meridians are liver, lung, spleen, kidney, and stomach meridians. There are 34 second-order association rules, 256 third-order association rules, 379 fourth-order association rules, and 137 fifth-order association rules. Eight clustered prescription combinations were obtained through cluster analysis. Conclusions Professor Huang Ping's treatment of tinnitus emphasises the co-regulation of the liver, spleen and stomach, with the main treatment principle being to excavate the liver and regulating qi, strengthen the spleen and resolve dampness, eliminate food and harmonise the stomach.

Key words: Tinnitus, R language, Data mining, Medication rule

CLC Number: 

  • R764.45
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