Abstract: To investigate the therapeutic effects of Nasonex Nasal Spray(momestasone furoate) and Rhinocort Nasal Spray(budesonide) on allergic rhinitis(AR). Methods160 patients with AR were randomly divided into two groups: the Nasonex group (n=80) were treated with Nasonex once daily (total 200μg) and the Rhinocort group (n=80) were treated with Rhinocort once daily (total 256μg) for 4 weeks. Clinical effects and adverse drug reactions were observed. ResultsThere were statistical differences between the pre-and post-treatment groups (both P＜0.05). The total effective rate was 97.5% in the Nasonex group and 92.5% in the Rhinocort group, however, there was no statistical difference between the two groups (P＞0.05). No severe adverse drug reaction was found in either group. ConclusionsBoth medicines have good therapeutic effects on allergic rhinitis. Either one can be used for allergic rhinitis alone and achieve ideal therapeutic efficacies.

Key words: allergic, perennial, Rhinitis, Momestasone furoate, Budesonide, Controlled clinical trials