JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2017, Vol. 31 ›› Issue (3): 22-27.doi: 10.6040/j.issn.1673-3770.0.2017.151

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Nasal irrigation and its role in the treatment of allergic rhinitis.

GUAN Kai, LI Lisha   

  1. Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100730, China
  • Received:2017-04-10 Online:2017-06-16 Published:2017-06-16

Abstract: Nasal irrigation is a safe, convenient, well-tolerated, and easy-to-accept local physical therapy for the supplementary treatment of allergic rhinitis(AR). It improves the rheological properties of mucus, and opens the nasal passage by removing allergens and inflammatory mucins to improve mucociliary function. Common nasal irrigation devices comprise a sprayer, an atomizer, and a squeeze-bottle. Washing liquid contains sodium, magnesium, zinc, calcium, potassium, and bicarbonate ions, all of which play an important role in the epithelial cells. At a pH<7 or pH>10, washing liquid inhibits ciliary beat-frequency, and saccharin tests have confirmed that 3%-5% washing liquid enhances nasal mucociliary clearance in healthy subjects, whilst washing liquid heated to 40 ℃ significantly reduces AR visual analog scale scores as well as histamine release. Seawater, in particular, significantly increases cell growth, more than saline or diluted seawater. Sodium pyruvate has both antioxidant and anti-inflammatory effects, thus nasal spray containing sodium pyruvate serves to both alleviate the symptoms of conjunctivitis in seasonal AR patients as well as reduce the requirement for nasal corticosteroids. Therefore, nasal irrigation can help reduce the amount of AR drugs needed.

Key words: Preventive treatment, Nasal irrigation, Allergic rhinitis

CLC Number: 

  • R765.21
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