Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (4): 149-154.doi: 10.6040/j.issn.1673-3770.0.2018.266

Previous Articles     Next Articles

Research of the relationship between adenoid hypertrophy and the common diseases of pediatric otolaryngology

LIU Yan, WEI Ping, KOU Wei, HU Sijie, WU Xiaofang, LIU Mengya, CHEN Cheng, YAO Hongbing   

  1. Department of Otorhinolaryngology Head and Neck Surgery, Children′s Hospital Affiliated to Chongqing Medical University, Chongqing 400014, China
  • Online:2019-07-20 Published:2019-07-22

PDF (PC)

580

Abstract: Adenoid hypertrophy(AH)is a common and frequently occurring disease in pediatric otorhinolaryngology. The etiology, clinical symptoms, and treatment methods of AH have been studied thoroughly and a consensus has been largely reached. However, the relationship between AH and otorhinolaryngology-related diseases has not been widely investigated. AH and allergic rhinitis(AR), acute and chronic rhinosinusitis(ARS/CRS), acute otitis media(AOM), otitis media effusion(OME), cholesteatoma otitis media(COM), acute and chronic tonsillitis(AT/CT), tonsillar hypertrophy(TH), obstructive sleep apnea syndrome(OSAS), and other pharyngeal diseases are inextricably linked. This article mainly discusses the relationship between AH and common pediatric otolaryngology diseases through the interaction and influence of AH on these diseases.

Key words: Adenoid hypertrophy, Allergic rhinitis, Rhinosinusitis, Otitis media, Obstructiue sleep apnea syndrome

CLC Number: 

  • R76
[1] Dogru M, Evcimik MF, Calim OF. Does adenoid hypertrophy affect disease severity in children with allergic rhinitis[J]. Eur Arch Otorhinolaryngol, 2017,27(1):209-213.doi: 10.1007/s00405-016-4196-x.
[2] 李明华.过敏性鼻炎与腺样体肥大[J].中国临床医生杂志,2014,42(12):9-10. doi: 10.3969/j.issn.2095-8552.2014.12.005. LI Minghua. Allergic rhinitis and adenoid hypertrophy[J]. Chin J Clin, 2014, 42(12): 9-10. doi: 10.3969/j.issn.2095-8552.2014.12.005.
[3] Warman M, Granot E, Halperin D. Improvement in allergic and nonallergic rhinitis: a secondary benefit of adenoidectomy in children[J]. Ear Nose Throat J, 2015, 94(6):220,222,224-227.
[4] Toskala E. Immunology[J]. Int Forum Allergy Rhinol, 2014, 4(Suppl 2):21-27. doi: 10.1002/alr.21380.
[5] Cho KS, Kim SH, Hong SL, et al. Local atopy in childhood adenotonsillar hypertrophy[J]. Am J Rhinol Allergy, 2018, 32(3):160-166. doi: 10.1177/1945892418765003.
[6] 文春秀, 谢小娟, 甘金梅, 等.粉尘螨滴剂通过改善机体免疫功能治疗过敏性鼻炎[J].中国免疫学杂志,2016,32(2):244-246,250.doi: 10.3969/j.issn.1000484x.2016.02.022. WEN Chunxiu, XIE Xiaojuan, GAN Jinmei, et al. Dust mite drops treat allergic rhinitis by improving the immune function of the body[J]. Chin J Immunol, 2016, 32(2): 244-246,250.doi: 10.3969/j.issn.1000484x.2016.02.022.
[7] Shokouhi F, Meymaneh Jahromi A, Majidi MR, et al. Montelukast in adenoid hypertrophy: its effect on size and symptoms[J]. Iran J Otorhinolaryngol, 2015, 27(83):443-448.
[8] Quaranta N, Milella C, Iannuzzi L, et al. A study of the role of different forms of chronic rhinitis in the development of otitis media with effusion in children affected by adenoid hypertrophy[J]. Int J Pediatr Otorhinolaryngol, 2013, 77(12):1980-1983. doi: 10.1016/j.ijporl.2013.09.017.
[9] Badr DT, Gaffin JM, Phipatanakul W. Pediatric rhinosinusitis[J]. Curr Treat Options Allergy, 2016, 3(3):268-281.doi: 10.1007/s40521-016-0096-y.
[10] 李瀛, 罗颜, 曹忠胜.低温等离子射频消融术治疗儿童慢性鼻窦炎伴腺样体肥大的临床效果观察[J].中国医学前沿杂志(电子版),2017,9(4):139-142. doi: 10.12037/YXQY.2017.04-34. LI Ying, LUO Yan, CAO Zhongsheng. The clinical effect of low temperature plasma radiofrequency ablation in the treatment of chronic sinusitis with adenoid hypertrophy in children[J]. Chin J Fron Med Sci( Elec Ver), 2017, 9(4): 139-142. doi: 10.12037/YXQY.2017.04-34.
[11] 林和, 谭业农. 腺样体切除对儿童慢性鼻窦炎治疗效果的影响[J].中国中西医结合耳鼻咽喉科杂志,2017,25(2):109-111.doi: 10.16542/j.cnki.issn.1007-4856.2017.02.009. LIN He, TAN Yenong.Effects of adenoidectomy on the treatment of chronic sinusitis in children[J]. Chin J Otorhinolaryngol Integ Med, 2017, 25(2): 109-111. doi: 10.16542/j.cnki.issn.1007-4856.2017.02.009.
[12] 毛敏, 张建国, 陶爱林, 等.腺样体切除术对鼻腔黏膜纤毛清除功能的影响[J].中国耳鼻咽喉颅底外科杂志,2016,22(1):50-53.doi: 10.11798/j.issn.1007-1520.201601012. MAO Min, ZHANG Jianguo, TAO Ailin, et al.The effect of adenoidectomy on the removal of nasal mucosal cilia[J].Chin J Otorhinolaryngol Skull Base Surg, 2016, 22(1): 50-53.doi: 10.11798/j.issn.1007-1520.201601012.
[13] Capaccio P, Torretta S, Marciante GA, et al.Endoscopic adenoidectomy in children with otitis media with effusion and mild hearing loss[J]. Clin Exp Otorhinolaryngol, 2016, 9(1):33-38.doi: 10.21053/ceo.2016.9.1.33.
[14] Pereira L, Monyror J, Almeida FT, et al. Prevalence of adenoid hypertrophy: a systematic review and meta-analysis[J]. Sleep Med Rev, 2018, 38:101-112. doi: 10.1016/j.smrv.2017.06.001.
[15] Cengel S, Akyol MU. The role of topical nasal steroids in the treatment of children with otitis media with effusion and/or adenoid hypertrophy[J]. Int J Pediatr Otorhinolaryngol, 2006, 70(4):639-645.doi: 10.1016/j.ijporl.2005.08.013.
[16] 高永平, 田从哲, 刘会清, 等.小儿腺样体肥大与分泌性中耳炎[J].中华耳科学杂志,2014,12(1):106-108.doi: 10.3969/j.issn.1672-2922.2014.01.026. GAO Yongping, TIAN Congzhe, LIU Huiqing, et al. Adenoid hypertrophy and secretory otitis media in children[J]. Chin J Otology, 2014, 12(1): 106-108. doi: 10.3969/j.issn.1672-2922.2014.01.026.
[17] Saafan ME, Ibrahim WS, Tomoum MO.Role of adenoid biofilm in chronic otitis media with effusion in children[J]. Eur Arch Otorhinolaryngol, 2013, 270(9):2417-2425. doi: 10.1007/s00405-012-2259-1.
[18] Gunel C, Ermisler B, Basak HS.The effect of adenoid hypertrophy on tympanometric findings in children without hearing loss[J]. Kulak Burun Bogaz Ihtis Derg, 2014, 24(6):334-338.doi: 10.5606/kbbihtisas.2014.50024.
[19] Khayat FJ, Talat Shareef LA. Association between size of adenoid and otitis media with effusion among a sample of primary school age children in Erbil City[J]. Diyal J Med, 2013, 5(2):1-10.
[20] Skoloudik L, Kalfert D, Valenta T, et al. Relation between adenoid size and otitis media with effusion[J]. Eur Ann Otorhinolaryngol Head Neck Dis, 2018, 135(6):399-402. doi: 10.1016/j.anorl.2017.11.011.
[21] Mikals SJ, Brigger MT.Adenoidectomy as an adjuvant to primary tympanostomy tube placement: a systematic review and meta-analysis[J]. JAMA Otolaryngol Head Neck Surg, 2014, 140(2):95-101.doi: 10.1001/jamaoto.2013.5842.
[22] Kocyigit M, Ortekin SG, Cakabay T, et al. Frequency of serous otitis media in children without otolaryngological symptoms[J]. Int Arch Otorhinolaryngol, 2017, 21(2):161-164.doi: 10.1055/s-0036-1584362.
[23] Torretta S, Pignataro L, Carioli D, et al. Phenotype profiling and allergy in otitis-prone children[J]. Front Pediatr, 2018,6:383.doi: 10.3389/fped.2018.00383.
[24] Salah M, Abdel-Aziz M, Al-Farok A, et al. Recurrent acute otitis media in infants: analysis of risk factors[J]. Int J Pediatr Otorhinolaryngol, 2013, 77(10):1665-1669. doi: 10.1016/j.ijporl.2013.07.022.
[25] Granath A. Recurrent acute otitis media: what are the options for treatment and prevention[J]. Curr Otorhinolaryngol Rep, 2017, 5(2):93-100. doi: 10.1007/s40136-017-0151-7.
[26] Maniu A, Harabagiu O, Perde Schrepler M, et al. Molecular biology of cholesteatoma[J]. Rom J Morphol Embryol, 2014, 55(1):7-13.
[27] 徐斌,付勇,舒强.儿童中耳胆脂瘤的临床特点及治疗[J].中华耳科学杂志,2016,14(1):67-70.doi: 10.3969/j.issn.1672-2922.2016.01.014. XU Bin, FU Yong, SHU Qiang. Clinical characteristics and treatment of middle ear cholesteatoma in children[J]. Chin J Otology, 2016, 14(1): 67-70. doi: 10.3969/j.issn.1672-2922.2016.01.014.
[28] Zautner AE. Adenotonsillar Disease[J]. Recent Pat Inflamm Allergy Drug Discov, 2012, 6(2):121-129.doi: 10.2174/187221312800166877.
[29] Morita Y, Yamamoto Y, Oshima S, et al. Pediatric middle ear cholesteatoma: the comparative study of congenital cholesteatoma and acquired cholesteatoma[J]. Eur Arch Otorhinolaryngol, 2016, 273(5):1155-1160.doi: 10.1007/s00405-015-3679-5.
[30] Babademez MA, Gul F, Muz E, et al. Impact of partial and total tonsillectomy on adenoid regrowth[J]. Laryngoscope, 2017, 127(3):753-756. doi: 10.1002/lary.25982.
[31] Tagaya M, Nakata S, Yasuma F, et al. Relationship between adenoid size and severity of obstructive sleep apnea in preschool children[J]. Int J Pediatr Otorhinolaryngol, 2012, 76(12):1827-1830.doi: 10.1016/j.ijporl.2012.09.010.
[32] 沈翎, 林宗通, 林兴, 等.儿童阻塞性睡眠呼吸暂停低通气综合征危险因素的病例对照研究[J].山东大学耳鼻喉眼学报,2018,32(2):25-29. doi: 10.6040/j.issn.1673-3770.0.2018.086. SHEN Ling, LIN Zongtong, LIN Xing, et al. Case-control study of risk factors for obstructive sleep apnea hypopnea syndrome in children[J]. J Otolaryngol Ophthalmol Shandong Univ, 2018, 32(2): 25-29.doi: 10.6040/j.issn.1673-3770.0.2018.086.
[33] Suri JC, Sen MK, Venkatachalam VP, et al.Outcome of adenotonsillectomy for children with sleep apnea[J]. Sleep Med, 2015, 16(10):1181-1186. doi: 10.1016/j.sleep.2015.02.539.
[34] Simsek G, Karacayli C, Ozel A, et al. Blood parameters as indicators of upper airway obstruction in children with adenoid or adenotonsillar hypertrophy[J]. J Craniofac Surg, 2015, 26(3):e213-216. doi: 10.1097/SCS.0000000000001437.
[35] Faden H, Callanan V, Pizzuto M, et al.The ubiquity of asymptomatic respiratory viral infections in the tonsils and adenoids of children and their impact on airway obstruction[J]. Int J Pediatr Otorhinolaryngol, 2016, 90:128-132. doi: 10.1016/j.ijporl.2016.09.006.
[36] Goldstein NA, Gorynski M, Yip C, et al.Developmental delay in young children with sleep-disordered breathing before and after tonsil and adenoid surgery[J]. Int J Pediatr Otorhinolaryngol, 2016, 85:107-111.doi: 10.1016/j.ijporl.2016.03.022.
[37] 李文生,沈康,赵征.腺样体肥大与白细胞介素6及耳鼻咽喉并发症的相关性分析[J].中国耳鼻咽喉头颈外科,2013,20(1):47-49.doi: 10. 16066/ j. 1672 7002. 2013. 01. 010. LI Wensheng, SHEN Kang, ZHAO Zheng. Correlation analysis of adenoid hypertrophy with IL-6 and complications of otorhinolaryngology[J]. Chin Arch Otolaryngol Head Neck Surg, 2013, 20(1):47-49.doi: 10. 16066/ j. 1672 7002. 2013. 01. 010.
[38] 张虹.儿童腺样体肥大对下颌骨发育的影响[J].临床耳鼻咽喉头颈外科杂志,2013,27(17):955-958.doi: 10.13201/j.issn.1001-1781.2013.17.016. ZHANG Hong. Effects of adenoid hypertrophy on the development of mandible in children[J]. J Clin Otorhinolaryngol Head Neck Surg, 2013, 27(17): 955-958. doi: 10.13201/j.issn.1001-1781.2013.17.016.
[39] Brunelli V, Lione R, Franchi L, et al. Maxillary dentoskeletal changes 1-year after adenotonsillectomy[J]. Int J Pediatr Otorhinolaryngol, 2016, 86:135-141. doi: 10.1016/j.ijporl.2016.04.027.
[40] Bozzini MF, Di Francesco RC. Managing obstructive sleep apnoea in children: the role of craniofacial morphology[J]. Clinics, 2016, 71(11):664-666. doi: 10.6061/clinics/2016(11)08.
[41] Eom TH, Jang ES, Kim YH, et al.Articulation error of children with adenoid hypertrophy[J]. Korean J Pediatr, 2014, 57(7):323-328. doi: 10.3345/kjp.2014.57.7.323.
[42] Gomaa MA, Mohammed HM, Abdalla AA, et al. Effect of adenoid hypertrophy on the voice and laryngeal mucosa in children[J]. Int J Pediatr Otorhinolaryngol, 2013, 77(12):1936-1939.doi: 10.1016/j.ijporl.2013.08.039.
[1] NI Jing, LEI Fei, BAI Dan, ZHOU Yun, MA Jianmei, HUANG Wei, WANG Chunyang. Expression of immunological markers in middle ear effusion in children with secretory otitis media [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 56-59.
[2] ZHANG Guiyang, HUANG He, XIAN Zhi, ZHANG Hanwen, XIE Guicai. Evaluation of clinical effects of sublingual immunotherapy with Dermatophagoides farinae drops in patients of different age groups with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(4): 60-65.
[3] Junjun QIAN,Wencheng ZHOU,Zhongfei WU,Dongyun BU,Liqin WANG,Meiping LU,Lei CHENG. Analysis of sensitization to inhalant allergens in patients with allergic rhinitis from Jiangsu and Anhui areas [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 147-151.
[4] Huiqin TIAN,Zhongfei WU,Ying LU,Lei CHENG. Association of vitamin D binding protein geneand CYP27B1 gene polymorphisms with mite-sensitized persistent allergic rhinitis among Han Chinese population [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 71-78.
[5] Ruoxi CHEN,Qingzhao ZHANG,Meiping LU,Xinjie ZHU,Lei CHENG. Association of Toll-like receptor pathway gene polymorphisms with allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 79-87.
[6] Changyu QIU,Jun ZHOU,De′en ZHUANG,Qing YANG,Meiping LU,Lei CHENG. Artificial intelligence technology application in disclosing allergic rhinitis patients′ needs to otolaryngologists [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 88-94.
[7] Huabin LI,Yuting LAI,Wenxiu JIANG. Endotypes and precision medicine in chronic sinusitis treatment [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 9-13.
[8] Meiping LU,Lei CHENG. Current status of genetic research on allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(3): 36-41.
[9] ZHANG Haoliang, YU Feng, WU Yunwen. Analysis of treatment approaches for chronic suppurative otitis media with eustachian tube dysfunction [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(2): 72-75.
[10] Yinshi GUO,Hui LU. Research progress of group Ⅱ innate lymphoid cells in the allergic rhinitis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 9-12.
[11] Qianhui QIU,Junxiao GAO. Synchronous control and long-term efficacy of specific immunotherapy for allergic rhinitis and asthma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 33-37.
[12] Hongmeng YU,Zhuofu LIU,Qi DAI. Endoscopic sinus surgery for chronic sinusitis with asthma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 38-41.
[13] Yu ZHANG,Xicheng SONG. Advances in interaction mechanisms and treatment strategy between chronic rhinosinusitis with nasal polyp and asthma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 49-52.
[14] Qintai YANG. Paying attention to the 'lateral airway' allergic diseases in children [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 59-62.
[15] QIN Ya′nan, WANG Lin, JIANG Yan, YAN Shu, CHEN Min, YU Longgang, LI Na. Characteristics of the distribution of inhaled allergens in patients with allergic rhinitis in Qingdao from 2008 to 2017 [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 67-72.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(1): 84 -87 .
[2] NIU Shanli,CHAI Maowen,LI Zhenxiu . Endoscopic rhinoplasty of inferior turbinate in 60 patients with chronic hypertrophic rhinitis[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2006, 20(1): 16 -18 .
[3] MENG Qing-guo,LU Yong-tian,FAN Xian-liang .

Association of killer cell immunoglobulin-like receptor gene polymorphisms with nasopharyngeal carcinoma

[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 196 -199 .
[4] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 199 -199 .
[5] WAN Li-jia,LU Hai-tao,JIANG Yi-dao,LIU Hui,LI Qin,SHE La-zhi . Effect of H-uvulopalatopharyngoplasty on obstructive sleep apnea
hypopnea syndrome[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 204 -205 .
[6] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 222 -224 .
[7] JI Xiao-bin,DENG Jia-de,ZANG Lin-quan,WANG Lei,XIE Jun . Blood histamine in guinea pigs with allergic rhinitis[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 228 -230 .
[8] . [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 253 -257 .
[9]
YIN Guo-hua,ZHONG Xiao . Long-term effect of laser reduction on lingua adenoids
[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 280 -282 .
[10] LIU Lian-he . Clinical analysis of 21 cases of neck cut injury[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2008, 22(3): 283 -284 .
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd