Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (4): 108-113.doi: 10.6040/j.issn.1673-3770.0.2021.445

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Research progress on the pathogenesis and clinical characteristics of BPPV secondary to inner ear diseases

HUANG Lan1, GAO Wei2Overview,CHEN Ganggang2Guidance   

  1. 1. Shanxi Medical University, Taiyuan 030001, Shanxi, China;
    2. Department of Otorhinolaryngology & Head and Neck Surgery, the first Hospital of Shanxi Medical University/Shanxi key Laboratory of Otorhinolaryngology/Institute of Otorhinolaryngology, Shanxi Medical University, Taiyuan 030001, Shanxi, China
  • Published:2022-07-11

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Abstract: Benign paroxysmal positional vertigo(BPPV)is one of the most common peripheral vestibular dysfunction diseases, which can be divided into idiopathic and secondary BPPV. Exogenous disease is considered to be the most important risk factor for secondary BPPV. In addition to history of ear trauma and inner ear surgery, common inner ear diseases, including Meniere's disease, sudden sensorineural hearing loss, vestibular neuritis, and vestibular migraine, may also result in secondary BPPV. Moreover, secondary BPPV can occur at any stage of inner ear disease with similar clinical manifestations. Therefore, this paper aimed to systematically review relevant national and international literature, as well as summarize and analyze the pathogenesis and clinical characteristics of BPPV secondary to common inner ear diseases, as a reference for clinical diagnosis and treatment.

Key words: Inner ear diseases, Secondary BPPV, Meniere's disease, Sudden sensorineural hearing loss, Vestibular neuriti, Vestibular migraine

CLC Number: 

  • R764.3
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[2] To analyze the clinical outcomes of patients with unilateral idiopathic sudden sensorineural hearing loss(SSNHL)and explore the relationship between vestibular function and prognosis in patients with SSNHL. MethodsA retrospective analysis of patients( ears)with SSNHL was performed. A total of vestibular function tests were performed in all patients to assess the influence of vestibular functions on the clinical outcome of SSNHL. ResultsTreatments were less effective in patients with abnormalities in ocular vestibular evoked myogenic potential(oVEMP)or cervical vestibular evoked myogenic potential(cVEMP). Those with normal oVEMP and cVEMP had relatively better hearing recovery. The outcomes of the caloric test or video head impulse test showed no association with the efficacy of treatment or hearing recovery in patients with SSNHL. Treatment was less effective in patients with abnormalities in both oVEMP and cVEMP, who also had worse hearing recovery than those who had an abnormal finding in only one of the two tests. ConclusionsPatients with abnormal oVEMP or cVEMP results had poor clinical outcomes, while those with normal oVEMP and cVEMP demonstrated better hearing recovery with treatment. Thus, oVEMP and cVEMP could be effective indices to predict the prognosis of patients with SSNHL. An abnormal vestibular function is a definite indicator of a wider and more severe pathological change in the inner ear of patients with SSNHL.. Clinical value of vestibular evoked myogenic potential to predict prognosis of unilateral idiopathic sudden sensorineural hearing loss [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 27-32.
[3] To analyze the relationship between vestibular symptoms and function and hearing outcomes in patients with unilateral profound sudden sensorineural hearing loss(SSNHL). MethodsA retrospective analysis of patients with unilateral profound SSNHL was performed. Vestibular symptoms and the results of ocular vestibular evoked myogenic potential(oVEMP), cervical vestibular evoked myogenic potential(cVEMP), video head impulse test(vHIT), and caloric test were analyzed to observe the relationship between hearing outcomes and vestibular symptoms and function. ResultsOf patients with unilateral profound SSNHL, there was a significant difference between the patients with and without vestibular symptoms, patients with vestibular dysfunction, and those with normal vestibular function. Patients with abnormal oVEMP, cVEMP, vHIT, and caloric test results showed a lower total effective rate. In contrast, patients with normal results in all four tests had a higher hearing recovery. ConclusionPatients with unilateral profound SSNHL with abnormal vestibular dysfunction and symptoms had a poor curative effect. Conversely, those with normal oVEMP, cVEMP, vHIT, and caloric test results had better chances of hearing recovery. Abnormal vestibular function suggests more extensive and severe inner ear lesions in patients with unilateral profound SSNHL.. Relationship between prognosis and vestibular symptoms/function in patients with unilateral profound sudden sensorineural hearing loss: A retrospective analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 33-38.
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