JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (2): 24-27.doi: 10.6040/j.issn.1673-3770.0.2014.316

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Three different routes of administration in the treatment of sudden sensorineural hearing loss

LU Na   

  1. Department of Otolaryngology, Cangzhou Central Hospital, Cangzhou 061001, Hebei, China
  • Received:2014-09-18 Online:2015-04-16 Published:2015-04-16

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Abstract: Objective To explore the best route of administration in the treatment of sudden sensorineural hearing loss. Methods According to the best route of administration. 210 sudden sensorineural hearing loss patients were divided into the venous group(70 patients injected dexamethasone via vein), the tympanic group(70 patients injected methylprednisolone into tympanic cavity), and the retroauricular group (70 patients injected methylprednisolone subperiosteally in the mastoid). Results The cure and effective rates of the three groups were 29.58%, 64.79%, 35.21%, 80.28%, and 64.79%, 83.10%, respectively. As for thecure rate,there were significant differences between the vein group and the retroauricular group(P<0.01), the tympanic group and the retroauricular group(P<0.01), but there were not significant differences between the vein group and the tympanic group(P>0.05). For the effective rates, there were significant differences between the vein group and the retroauricular group(P<0.01), the vein group and the tympanic group(P<0.01), but there were not significant differences between the tympanic group and the retroauricular group(P>0.05). Conclusion injecting methylprednisolone subperiosteally in the mastoid shows a high cure rate and stable effective rate sudden sensorineural hearing loss.

Key words: Eardrum puncture, Back ear injection, Sudden sensorineural hearing loss, Glucocorticoid, Vein

CLC Number: 

  • R764.43
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