Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2023, Vol. 37 ›› Issue (5): 68-73.doi: 10.6040/j.issn.1673-3770.0.2022.469

• Original Article • Previous Articles     Next Articles

Kujiu decoction for refractory pharyngeal ulceration: a case report and literature review

YAO Yuning1, ZHANG Longsheng1, SUN Jing2, CAO Kegang3   

  1. 1. Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine, Beijing 100700, China2. Tongzhou District, Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine, Beijing 101121, China3. Beijing University of Traditional Chinese Medicine Brain Disease Research Institute, Beijing 100027, China
  • Published:2023-10-13

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Abstract: Objective To report a case of refractory pharyngeal ulceration treated with Kujiu decoction according to the ancient Chinese literature, Shanghanlun, and study the specific syndrome and formulation of Kujiu decoction. Methods This study reviewed and summarized the diagnosis and treatment process of a case of refractory pharyngeal ulceration that was treated with Kujiu decoction. Findings from a review of the literature on the prescription, formulation, and indications of Kujiu decoction were summarized. Results Kujiu decoction was effective for pharyngalgia, pharyngeal ulcerations, and aphonia caused by “Shaoyin disease” and “Yin deficiency and fire exuberance syndromes”. Vinegar can be used as Kujiu. In Kujiu decoction, Kujiu, pinellia, and albumen were used together to achieve the effects of nourishing yin, clearing heat, and resolving phlegm, which in turn, treated pharyngalgia and pharyngeal ulceration. Zhang Zhongjing's method of adding albumen after the temperature of the decoction became lukewarm may enhance the effects. Clinically, Kujiu decoction can be used to treat acute and chronic pharyngitis, aphonia, laryngogenic cough, globus hysteriocus, and oral ulcerations after radiotherapy. Conclusion Kujiu decoction has definite clinical efficacy in the treatment of pharyngeal ulcerations and other pharyngeal diseases. Further studies on the optimal decoction formulation are warranted. Furthermore, in the future, studies that investigate its clinical applications and mechanisms of action are also necessary.

Key words: Shang han lun(Treatise on febrile diseases), Kujiu decoction, Pharyngeal ulcer, Decoction

CLC Number: 

  • R276.1
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