JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2015, Vol. 29 ›› Issue (3): 72-75.doi: 10.6040/j.issn.1673-3770.0.2015.076

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Effect of intravitreal ranibizumab injection combined with trabelectomy and panretinal photocoagulation for neovascular glaucoma

CHAI Xuerong, ZHANG Shixi, TAO Yu, SHEN Jiaquan   

  1. Department of Ophthalmology, Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China
  • Received:2015-02-04 Revised:2015-04-17 Published:2015-06-16

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Abstract: Objective To evaluate the efficacy and safety of intravitreal ranibizumab injection combined with trabelectomy and panretinal photocoagulation (PRP) in treatment of neovascular glaucoma. Methods Twenty-four patients (24 eyes) with neovascular glaucoma who underwent intravitreal ranibizumab injection combined with trabelectomy and PRP between December 2013 and May 2014 at Shandong Provicial Hospital were observed. During a follow-up period of 8.6±1.7 months, the pre-operative and post-operative visual acuity(VA), intraocular pressure (IOP) and number of anti-glaucoma medications, also the surgical complications and success rate were observed. Results Post-operative IOP was 10.9±2.7 mmHg, 13.3±3.2 mmHg, 14.0±3.4 mmHg and 15.4±5.1 mmHg at 1 week and 1, 3 and 6 months after the surgery, which was significantly decreased compared with pre-operative one(P<0.01). The number of anti -glaucoma medications was 0.2±0.5, 0.4±0.7, 0.4±0.8 and 0.5±1.0 at 1 week and 1, 3 and 6 months after the surgery, which was significantly decreased compared with the pre-treatment one(P<0.01). At the last visit, there were 14 eyes with stable VA, 8 with VA improvement, and 2 with diminished VA. Conclusion Intravitreal ranibizumab injection combined with trabelectomy and PRP is effective and safe for neovascular glaucoma.

Key words: Neovascular glaucoma, Ranibizumab, Intravitreal injection, Trabelectomy, Panretinal photocoagulation

CLC Number: 

  • R775.3
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