Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (5): 6-10.doi: 10.6040/j.issn.1673-3770.0.2021.404

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Application value of distortion product otoacoustic emission and high stimulation rate auditory brainstem response in patients with normal hearing tinnitus

DUAN Xinyan1,2, SONG Zhongyi2, WANG Ning2, ZI Xicun3, PAN Xinliang1,2   

  1. 1. Department of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China;
    2. Department of Otorhinolaryngology Head and Neck Surgery, Qilu Hospital of Shandong University(Qingdao), Qingdao 266035, Shandong, China;
    3. Outpatient Unit, Qilu Hospital of Shandong University(Qingdao), Qingdao 266035, Shandong, China
  • Published:2022-09-20

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Abstract: Objective This study aimed to observe and analyze the characteristics of distortion product otoacoustic emission(DPOAE)and high stimulation rate auditory brainstem response(ABR)in tinnitus patients with normal hearing and to explore their application value in tinnitus assessment. Methods Thirty-one(46 ears)young tinnitus patients with normal hearing were selected as the tinnitus group, and 25(50 ears)young people without tinnitus with normal hearing results were selected as the normal control group. Pure tone audiometry, acoustic conductance audiometry, DPOAE, and high and low stimulus rate ABR were detected, and the results in the tinnitus and healthy controls were compared. Results We found no significant difference in the detection rate of DPOAE and ABR wave Ⅰ, Ⅲ, and Ⅴ amplitudes with different stimulation rates between the two groups. The signal-to-noise ratio at 8 kHz in the tinnitus group was significantly lower than that in control group. Further, under a high stimulation rate, the Ⅰ~Ⅴ wave interval of tinnitus group was longer than that of the control group, and the difference was statistically significant(P<0.05). At two stimulus rates,the the wave Ⅰ latency difference was shorter and the wave Ⅴ latency difference was longer in the tinnitus group, indicating that the wave Ⅰ~Ⅴ interval difference was longer in the tinnitus group than in the control group(P<0.05). Conclusion DPOAE and high stimulation rate ABR can be used as an objective method to diagnose tinnitus and evaluate early tinnitus. Increasing the stimulation rate of ABR could improve the sensitivity of tinnitus detection.

Key words: Tinnitus, High and low stimulation rate, Auditory brainstem response, Distortion product otoacoustic emission

CLC Number: 

  • R764.45
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