Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2022, Vol. 36 ›› Issue (6): 106-110.doi: 10.6040/j.issn.1673-3770.0.2021.426

• 论著 • Previous Articles    

A case report of Leber's idiopathic stellate neuroretinitis and literature review

WANG Qian, LIU Na, WANG Shaopeng   

  1. Department of Ophthalmology, Zibo Central Hospital, Zibo 255022, Shandong, China
  • Published:2022-12-07

Abstract: Objective To discuss the diagnosis and treatment of Leber's idiopathic stellate neuroretinitis. Methods We reviewed the medical records of a 47-year-old male patient whose main complaint was that visual acuity of the right eye had beendecreased for 1 week and had worsened over the lastday. After systemic examination, fundus fluorescein angiography, and indocyanine green angiography, the patient was diagnosed with Leber's idiopathic stellate neuroretinitis in the right eye. The patient considered the side effects of the glucocorticoids and refused treatment. Results After 3 months of follow-up, the patient's vision improved to 0.8. Conclusion The etiology of Leber's idiopathic stellate neuroretinitis is unknown. It is necessary to exclude diseases with similar clinical manifestations but clear etiology. The first line of treatment for this disease is glucocorticoid anti-inflammatory therapy, which can be combined with antibiotics, antiviral, vasodilators and traditional Chinese medicine. The disease is self-limiting and generally has a good prognosis.

Key words: Neuroretinitis, Leber idiopathic stellate neuroretinitis, Fundus fluorescein angiography, Indocyanine green angiography, Glucocorticoid

CLC Number: 

  • R774
[1] Casson RJ, O'Day J, Crompton JL. Leber's idiopathic stellate neuroretinitis: differential diagnosis and approach to management[J]. Aust N Z J Ophthalmol, 1999, 27(1): 65-69. doi:10.1046/j.1440-1606.1999.00132.x.
[2] 滕岩, 王月春, 陈章明, 等. Leber特发性星芒状视神经视网膜炎二例[J]. 中华眼底病杂志, 1996(4):260.
[3] Sundaram SV, Purvin VA, Kawasaki A. Recurrent idiopathic neuroretinitis: natural history and effect of treatment[J]. Clin Exp Ophthalmol, 2010, 38(6): 591-596. doi:10.1111/j.1442-9071.2010.02298.x.
[4] Attawan A, Pepper IM, Hickman SJ. The natural history of idiopathic neuroretinitis[J]. Pract Neurol, 2015, 15(5): 387-388. doi:10.1136/practneurol-2015-001175.
[5] Abdelhakim A, Rasool N. Neuroretinitis: a review[J]. Curr Opin Ophthalmol, 2018, 29(6): 514-519. doi:10.1097/ICU.0000000000000527.
[6] Rodríguez-Castelblancoá, Cordero-Coma M. Leber's idiopathic stellate neuroretinitis: diagnostic and therapeutic conflicts[J]. Arch Soc Esp Oftalmol(Engl Ed), 2019, 94(8): 413-416. doi:10.1016/j.oftal.2019.02.003.
[7] Nabih O, Arab L, El Maaloum L, et al. Leber's idiopathic stellate neuroretinitis: a clinical case[J]. Ann Med Surg(Lond),2022, 76: 103491. doi:10.1016/j.amsu.2022.103491.
[8] 宋万卿, 李建军. 一例6岁女孩双眼Leber特发性星芒状视神经视网膜炎的恢复过程[J]. 眼科, 2011, 20(4): 234.
[9] 周丽霞, 柏春伟, 陶源. Leber特发性星芒状视神经视网膜炎1例[J]. 航空航天医药, 2008, 19(3): 176. doi:10.3969/j.issn.2095-1434.2008.03.034.
[10] 周平. Leber特发性星芒状视神经视网膜炎1例报告[J]. 广西医科大学学报, 2001, 18(3): 446. doi:10.16190/j.cnki.45-1211/r.2001.03.085.
[11] Pahor D. Leber's idiopathic stellate neuroretinitis[J]. Can J Ophthalmol, 2001, 36(6): 347-349. doi:10.1016/S0008-4182(01)80124-1.
[12] Vinci M, Fossarello M, Peiretti E. Infrared imaging of choroidal involvement in Leber's idiopathic stellate neuroretinitis[J]. ClinOphthalmolAuckl N Z, 2011, 5: 999-1002. doi:10.2147/OPTH.S22833.
[13] Carroll DM, Franklin RM. Leber's idiopathic stellate retinopathy[J]. AmJOphthalmol, 1982, 93(1): 96-101. doi:10.1016/0002-9394(82)90706-1.
[14] Suhler EB, Lauer AK, Rosenbaum JT. Prevalence of serologic evidence of cat scratch disease in patients with neuroretinitis[J]. Ophthalmology, 2000, 107(5): 871-876. doi:10.1016/s0161-6420(00)00002-6.
[15] Ormerod LD, Skolnick KA, Menosky MM, etal. Retinal and choroidal manifestations of cat-scratch disease[J]. Ophthalmology, 1998, 105(6): 1024-1031. doi:10.1016/S0161-6420(98)96003-1.
[16] Chi SL, Stinnett S, Eggenberger E, et al. Clinical characteristics in 53 patients with cat scratch optic neuropathy[J]. Ophthalmology, 2012, 119(1): 183-187. doi:10.1016/j.ophtha.2011.06.042.
[17] Solley WA, Martin DF, Newman NJ, et al. Cat scratch disease: posterior segment manifestations[J]. Ophthalmology, 1999, 106(8): 1546-1553.doi:10.1016/S0161-6420(99)90452-9.
[18] Zhang XM, Du Q, Ma FF, et al. Characteristics of syphilitic uveitis in Northern China[J]. BMC Ophthalmol, 2017, 17(1): 95. doi:10.1186/s12886-017-0491-6.
[19] 王胜男, 孙挥宇, 毛菲菲, 等. 141例神经梅毒患者眼部表现的临床分析[J]. 眼科, 2021, 30(5): 386-390. doi:10.13281/j.cnki.issn.1004-4469.2021.05.011. WANG Shengnan, SUN Huiyu, MAO Feifei, et al. Ophthalmologicalmanifestations of neurosyphilis in 141 cases[J]. Ophthalmology in China, 2021, 30(5): 386-390. doi:10.13281/j.cnki.issn.1004-4469.2021.05.011.
[20] Tsuboi M, Nishijima T, Yashiro S, et al. Prognosis of ocular syphilis in patients infected with HIV in the antiretroviral therapy era[J]. Sex Transm Infect, 2016, 92(8): 605-610. doi:10.1136/sextrans-2016-052568.
[21] 霍冬梅, 戴荣平, 董方田. 结核性脉络膜炎一例[J]. 中华眼科杂志, 2004, 40(10): 712-713. doi:10.3760/j:issn:0412-4081.2004.10.018.
[22] 杨培增, 漆剑. 不容忽视的结核性葡萄膜炎[J]. 中华眼科杂志, 2015, 51(10): 726-729. doi:10.3760/cma.j.issn.0412-4081.2015.10.003.
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