喉角化症的综合治疗

山东大学耳鼻喉眼学报

喉角化症的综合治疗

余崇仙，张琨龄，刘业海

安徽医科大学第一附院耳鼻咽喉-头颈外科，安徽合肥 230022

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-10-24 发布日期:2007-10-24
通讯作者: 余崇仙

Combined treatment on keratosis of the larynx

YU Chong-xian, ZHANG Kun-ling, LIU Ye-hai

Department of Otolaryngology & Head and Neck Surgery, First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui, China

Received:1900-01-01 Revised:1900-01-01 Online:2007-10-24 Published:2007-10-24
Contact: YU Chong-xian

摘要/Abstract

摘要： 目的探讨治疗喉角化郑的有效方法。方法对30例患者进行综合治疗，主要是在抗角化治疗的同时配合以辅助药物、局部湿化，去除病因，部分病例辅以手术治疗。结果随访1～5年，25例(83.3%)的病变在综合治疗后消失，2例复发，2例因癌变而分别行放疗和手术治疗，1例仍有镜下角化。结论对喉角化症行以抗角化治疗为主的综合治疗方法具有方便易行、疗效确切、无创伤等优点。

关键词: 喉角化症, 抗角化药物, 综合治疗, 癌前病变

Abstract: Objective To explore effective therapies for keratosis of the larynx, a pre-malignant precursor of squamous cell carcinoma. Methods From 2000 to 2003, 30 patients with keratosis of the larynx were given combined therapies which were mainly anticornification drugs, ancillary drugs, humidification treatment and surgery. Results All the patients were followed up from 1 to 5 years. Complete remission was observed in 25 of 30 patients (83.3%), partial response was seen in 1 patient and recurrence in 2. Meanwhile progression to carcinoma occurred in 2 cases. Conclusions These combined therapies have advantages of easy procedure, good effect and minor injury for keratosis of the larynx.

Key words: Keratosis of larynx, Anti-cornification drugs, Combined therapy, Precancerosis

中图分类号:

R739.65

余崇仙,张琨龄,刘业海 . 喉角化症的综合治疗[J]. 山东大学耳鼻喉眼学报, 2007, 21(5): 462-464 .

YU Chong-xian,ZHANG Kun-ling,LIU Ye-hai . Combined treatment on keratosis of the larynx[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2007, 21(5): 462-464 .

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