关键词: 放射性腭帆张肌损伤, 放射性中耳炎, 鼻咽癌

Abstract:

Objective   To study the relationship between radioactive otitis media and changes in cross section area of tensor veli palatine (TVP) muscle after radiotherapy in patients with nasopharyngeal carcinoma. Methods   Retrospectively analyze the clinical data of 36 patients with nasopharyngeal carcinoma who accepted radiotherapy in our hospital from January, 2007  to January, 2011. The cross section area (CSA) of TVP and medial pterygoid (MP) muscle of all the patients were measured before and after radiotherapy, meanwhile the incidence of SOM was surveyed after radiotherapy. Results   Twenty-four  cases (44 ears) developed post-irradiation SOM after the radiotherapy. STVP, SLTVP, SRTVP, SLTVPM, SRTVPM, SLTVPF, SRTVPF, SMP, SLMP and SRMP of all patients statistically decreased after radiotherapy (P<0.05). Ears with TVP atrophy had a high rate of incidence of SOM than ears without TVP atrophy (72.92% vs 37.50%, χ2=8.445, P=0.004). Conclusion   The atrophy occurs to the CSA of TVP and MP of patients with nasopharyngeal carcinoma, which may result in post-irradiation SOM.

Key words: Nasopharyngeal carcinoma, Radioactive otitis media, TVP muscle injury