山东大学耳鼻喉眼学报 ›› 2017, Vol. 31 ›› Issue (1): 119-122.doi: 10.6040/j.issn.1673-3770.0.2016.451

• 无栏目 • 上一篇    下一篇

光学相干断层扫描技术在非动脉炎性前部缺血性视神经病变中的诊断现状

焦芮1,韩克阳1,王淑雅2, 赵博军3   

  1. 1.山东中医药大学第二临床医学院, 山东 济南 250001;
    2.山东中医药大学附属眼科医院, 山东 济南 250003;
    3.山东大学附属省立医院眼科中心, 山东 济南 250021
  • 收稿日期:2016-10-30 出版日期:2017-02-16 发布日期:2017-02-16
  • 通讯作者: 赵博军. E-mail:zhaobojun@hotmail.com
  • 基金资助:
    山东省自然科学基金(ZR2015HM026)

The situation of optical coherence tomography in the diagnosis of non-arteritic anterior ischemic optic neuropathy.

  1. The Second School of Clinical Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250001, Shandong, China;2. Ophthalmic Hospital Affiliated to Shandong University of Traditional Chinese Medicine, Jinan 250003, Shandong, China;3. Ophthalmic Center, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China
  • Received:2016-10-30 Online:2017-02-16 Published:2017-02-16

PDF (PC)

816

被引次数

1

摘要： 非动脉炎性前部缺血性视神经病变(NA-AION)是一种中老年人常见急性致盲性眼病,临床表现为晨起或短暂休息后突发性的视力下降或视野缺损,视野缺损通常与生理盲点相连。目前,眼底和视野检查、荧光素眼底血管造影、视觉诱发电位是NA-AION常用的辅助检查手段。近年来,光学相干断层扫描技术(OCT)因具有无创、安全性高、分辨率高、扫描速度快、可三维重建和分层分析的特点已广泛用于NA-AION的诊疗中。本研究主要对OCT在NA-AION中的诊断现状及临床意义进行综述。

关键词: 视神经纤维层, 黄斑, 非动脉炎性前部缺血性视神经病变, 脉络膜, 光学相干断层扫描技术

Abstract: Non-arteritic anterior ischemic optic neuropathy(NA-AION)is a common disease which caused blindness among the middle-aged and old people. The clinical manifestations of NA-AION include sudden blurred vision or defect of visual field which often happens in the early morning or after short break, and the defect of visual field usually connects to physiological blind spots. At present, the examinations of fundus and visual field, fundus fluorescein angiography(FFA)and visual evoked potential(VEP)are helpful in the diagnosis of NA-AION. In recent years, optical coherence tomography(OCT)has been widely used in the diagnosis and treatment of NA-AION due to its characteristics of non-invasiveness, higher safety and resolution, rapid scanning, three-dimensional reconstruction and stratification analysis. In this article, the diagnostic situation and clinical significance of OCT in NA-AION was reviewed.

Key words: Non-arteritic anterior ischemic optic neuropathy, Macula lutea, Retinal nerve fiber layer, Choroid, Optical coherence tomography

中图分类号: 

  • R774.6
[1] Hayreh SS. Ischemic optic neuropathies-where are we now?[J]. Graefes Arch Clin Exp Ophthalmol, 2013, 251(8):1873-1884.
[2] 卢成戎, 魏世辉. 特发性(脱髓鞘性)视神经炎的流行病学诊断及治疗的展望[J]. 国际眼科杂志, 2008, 8(2):372- 374.
[3] Hedges TR 3rd, Vuong LN, Gonzalez-Garcia AO, et al. Subretinal fluid from anterior ischemic optic neuropathy demonstrated by optical coherence tomography[J]. Arch Ophthalmol, 2008, 126(6):812-815.
[4] Kardon RH. Role of the macula optical coherence tomography scan in neuro-ophthalmology[J]. J Neuroophthalmol, 2011, 31(4):353-361.
[5] Atkins EJ, Bruce BB, Newman NJ, et al. Treatment of nonarteritic anterior ischemic optic neuropathy[J]. Surv Ophthalmol, 2010, 55(1):47-63.
[6] Hayreh SS. Non-arteritic anterior ischemic optic neuropathy: role of systemic corticosteroid therapy[J]. Sur Ophthalmol, 2010, 55:399-400.
[7] Manousaridis K, Talks J. Macular ischemia: a contraindication for anti-VEGF treatment in retinal vascular disease?[J]. Br J Ophthalmol, 2012, 96(2):179-184.
[8] 马维娜. 光学相干断层扫描在非动脉炎性前部缺血性视神经病变中的应用[D]. 石家庄:河北医科大学, 2013.
[9] Barboni P, Savini G, Valentino ML, et al. Retinal nerve fiber layer evaluation by optical coherence tomography in Lebers hereditary optic neuropathy[J]. Ophthalmol, 2005, 112:120-126.
[10] Medeiros FA, Moura FC, Vessani RM, et al. Axonal loss after traumatic optic neuropathy documented by optical coherence tomography[J]. Ophthalmol, 2003, 135(3):406-408.
[11] Medeiros FA, Zangwill LM, Bowd C, et al. Comparison of the GDx VCC scanning laser polarimeter, HRT II confocal scanning laser ophthalmoscope, and stratus OCT optical coherence tomograph for the detection of glaucoma[J]. Arch Ophthalmol, 2004, 122(6):827-837.
[12] Bellusci C, Savini G, Carbonelli M, et al. Retinal nerve fiber layer thickness in nonarteritic anterior ischemic optic neuropathy: OCT characterization of the acute and resolving phases[J]. Graefes Arch Clin Exp Ophthalmol, 2008, 246(5):641-647.
[13] Li A, Li L, Li M, et al. A new characterization for nonarteritic anterior ischemic optic neuropathy[J]. Clin Exp Med, 2015, 8(10):18681-18688.
[14] Han M, Zhao C, Han QH, et al. Change of Retinal Nerve Layer Thickness in Non-Arteritic Anterior Ischemic Optic Neuropathy Revealed by Fourier Domain Optical Coherence Tomography[J]. Curr Eye Res, 2016, 41(8):1076-1081.
[15] Alasil T, Tan O, Lu AT, et al. Correlation of Fourier domain optical coherence tomography retinal nerve fiber layer maps with visual fields in nonarteritic ischemic optic neuropathy[J]. Ophthalmic Surg Lasers Imag, 2008, 39(4 Suppl):S71-S79.
[16] Contreras I, Noval S, Rebolleda G, et al. Follow-up of nonarteritic anterior ischemic optic neuropathy with optical coherence tomography[J]. Ophthalmol, 2007, 114(12):2338-2344.
[17] Hood DC, Anderson S, Rouleau J, et al. Retinal nerve fiber structure versus visual field function in patients with ischemic optic neuropathy. A test of a linear model[J]. Ophthalmol, 2008, 115(5):904-910.
[18] Kupersmith MJ, Anderson S, Durbin M, et al. Scanning laser polarimetry, but not optical coherence tomography predicts permanent visual field loss in acute nonarteritic anterior ischemic optic neuropathy[J]. Invest Ophthalmol Vis Sci, 2013, 54(8):5514-5519.
[19] Kernstock C, Beisse F, Wiethoff S, et al. Assessment of functional and morphometric endpoints in patients with non-arteritic anterior ischemic optic neuropathy(NAION)[J]. Graefes Arch Clin Exp Ophthalmol, 2014, 252(3):515-521.
[20] Aggarwal D, Tan O, Huang D, et al. Patterns of ganglion cell complex and nerve fiber layer loss in nonarteritic ischemic optic neuropathy by fourier-domain optical coherence tomography[J]. Invest Ophthalmol, 2012, 53(8):4539-4545.
[21] Papchenko T, Grainger BT, Savino PJ, et al. Macular thickness predictive of visual field sensitivity in ischaemic optic neuropathy[J]. Acta Ophthalmol, 2012, 90(6):e463-e469.
[22] Keller J, Oakley JD, Russakoff DB, et al. Changes in macular layers in the early course of non-arteritic ischaemic optic neuropathy[J]. Graefes Arch Clin Exp Ophthalmol, 2015, 254(3):561-567.
[23] Levin LA, Nilsson SE, Ver Hoeve J, et al. Adlers Physiology of the Eye[M].11th ed. New York: Saunders, Elsevier, 2011: Chapter 28.
[24] Fard MA, Abdi P, Kasaei A, et al. Peripapillary choroidal thickness in nonarteritic anterior ischemic optic neuropathy[J]. Invest Ophthalmol, 2015, 56:3027-3033.
[25] García-Basterra I, González Gómez A, García-Ben A, et al. Macular choroidal thickness in non-arteritic ischemic optic neuropathy[J]. Arch Soc Esp Oftalmol, 2016, 91(5):223-227.
[26] Jiang L, Chen L, Qiu X, et al. Choroidal thickness in Chinese patients with non-arteritic anterior ischemic optic neuropathy[J]. BMC Ophthalmol, 2016, 16(1):153.
[1] 赵娟,焦万珍,赵博军. UWFSS-OCTA检测糖尿病视网膜病变微循环的变化[J]. 山东大学耳鼻喉眼学报, 2026, 40(2): 80-86.
[2] 朱明琼,李征,刘茹,田涛,彭婧利,吕倩怡,谭华霞. 基于OCT/OCTA的AI筛查系统在抗VEGF治疗糖尿病性黄斑水肿患者效果评价中的应用[J]. 山东大学耳鼻喉眼学报, 2026, 40(1): 68-73.
[3] 孙庆祝,沈健,陈星,吴雁冰,曾论. 代谢指标在预测糖尿病性黄斑水肿患者雷珠单抗疗效中的作用[J]. 山东大学耳鼻喉眼学报, 2026, 40(1): 74-81.
[4] 朱云龙,王平,高萌. 误诊为中浆及视网膜炎的后巩膜炎1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2026, 40(1): 99-105.
[5] 宋艳玲,司元元,崔彦. 微量玻璃体切除治疗激光笔致儿童全层黄斑裂孔1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2025, 39(6): 144-147.
[6] 姚雪,陆小凤,张梦芮,胡馨雅,赵嘉洛,赖思思,李玄,刘子潇,沈超凡,范梓欣,张寅升,张国明. 基于YOLOv8模型辅助诊断斜肌功能异常[J]. 山东大学耳鼻喉眼学报, 2025, 39(5): 76-82.
[7] 丁术梁,王超凡,刘建亮. 眼内液检测指导精准治疗急性视网膜坏死1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2025, 39(5): 114-117.
[8] 王焕霞,王淑雅,王影,孙璇,黄杰,王兴荣. 孔源性视网膜脱离玻璃体切除术后继发黄斑前膜的危险因素分析[J]. 山东大学耳鼻喉眼学报, 2025, 39(4): 181-185.
[9] 毛一恒,冯洁,何润田. 高血脂对视网膜损害与脉络膜厚度关系研究[J]. 山东大学耳鼻喉眼学报, 2025, 39(3): 162-167.
[10] 肖哲,张胜娟,赵子琦,兴辰,李成泉,刘志强. Ultra Q:YAG激光治疗黄斑部视网膜前出血17例并文献复习[J]. 山东大学耳鼻喉眼学报, 2025, 39(1): 130-135.
[11] 张莉苑,郭颖卓,陈蛟,王华,钟定娟. 650 nm低能量红光联合角膜塑形镜控制近视的临床效果[J]. 山东大学耳鼻喉眼学报, 2024, 38(5): 52-57.
[12] 沈嘉琪,李潇飒,毕燕龙,张敬法. 人工智能在DME筛查、诊断和预后中的应用[J]. 山东大学耳鼻喉眼学报, 2024, 38(5): 153-159.
[13] 张金木,郭滨,蒋文君,刘冬梅. M受体信号通路在近视发生发展中作用的研究进展[J]. 山东大学耳鼻喉眼学报, 2024, 38(5): 160-164.
[14] 张莉苑,钟定娟,王华. 非手术的近视管理方法与脉络膜的研究进展[J]. 山东大学耳鼻喉眼学报, 2024, 38(4): 149-153.
[15] 鲍莹,刘志高,姜鹏飞,崔文轩,郑晓霞,杨梦瑶,司明威,王玉,王红. 康柏西普治疗糖尿病合并CRVO-ME高反射点的临床观察[J]. 山东大学耳鼻喉眼学报, 2024, 38(3): 55-60.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
网站版权所有 © 2018 《山东大学耳鼻喉眼学报》编辑部　
地址：山东省济南市山大南路27号（250100）电话：+86-0531-88366912 E-mail: ebhxb@sdu.edu.cn
本系统由北京玛格泰克科技发展有限公司设计开发