山东大学耳鼻喉眼学报 ›› 2014, Vol. 28 ›› Issue (5): 82-84.doi: 10.6040/j.issn.1673-3770.0.2014.147

• 论著 • 上一篇    下一篇

影响正常眼压性青光眼的血管因素研究

傅浩勤1, 毛文娟2, 张剑虹1, 许薇琦1, 朱圣洁1   

  1. 1. 上海市第一人民医院分院眼科, 上海 200081;
    2. 上海市第一人民医院分院超声波室, 上海 200081
  • 收稿日期:2014-05-04 发布日期:2014-10-16
  • 作者简介:傅浩勤。E-mail:fuhaoqin505@qq.com

Effect of vascular factors on normal tension glaucoma

FU Hao-qin1, MAO Wen-juan2, ZHANG Jian-hong1, XU Wei-qi1, ZHU Sheng-jie1   

  1. 1. Department of Ophthalmology, Branch of Shanghai First People's Hospital, Shanghai 200081, China;
    2. Department of Ultrasonic, Branch of Shanghai First People's Hospital, Shanghai 200081, China
  • Received:2014-05-04 Published:2014-10-16

摘要: 目的 观察血管因素对正常眼压性青光眼(NTG)的影响。方法 前瞻性地对NTG组40眼及年龄、性别相匹配的正常对照组40眼行彩色超声多普勒成像(CDFI)研究,分析颈总动脉(CA)、颈内动脉(ICA)、 眼动脉(OA)、视网膜中央动脉(CRA)和睫状后短动脉(SPCA)的收缩期峰值血流速度(PSV)、舒张末期血流速度(EDV)及阻力指数(RI)。结果 NTG组ICA、OA、CRA、 SPCA的PSV与正常对照组比较均降低 (P<0.01、P<0.05),RI则明显增高 (P<0.01), OA和CRA的EDV与正常对照组比较亦均降低 (P<0.01、P<0.05), ICA和SPCA的EDV与正常对照组比较差异无统计学意义(P>0.05),而CA的各项参数与正常对照组比较差异亦均无统计学意义(P>0.05)。结论 应将ICA 、OA、CRA、PCA的RI增高作为早期诊断NTG及判断预后的重要指标,同时亦应参考OA、CRA的EDV是否降低,以对NTG患者的预后及治疗方案提供有利信息。

关键词: 眼压, 超声多普勒, 彩色, 青光眼

Abstract: Objective To observe the effect of vascular factors on normal tension glaucoma(NTG). Methods The NTG group of 40 eyes,and the age and sex matched normal control group of 40 eyes were enrolled in this study. Color Doppler flow image (CDFI) was used to analyze the peak systolic velocity(PSV), the end diastolic velocity(EDV) and the resistance index(RI) of the carotid artery(CA), the internal carotid artery(ICA), the ophthalmic artery(OA), the central retinal artery(CRA) and the shortposterior ciliary artery(SPCA). Results The PSV of ICA,OA,CRA and SPCA in the NTG group was decreased (P<0.01, P<0.05) and RI was significantly increased (P<0.01).The EDV of OA and CRA in the NTG group compared with the normal control group was decreased (P<0.01, P<0.05), while the EDV of ICA and SPCA in the NTG group compared with the normal control group showed no significant difference (P>0.05), and the parameters of CA in the NTG group compared with the normal control group showed no significant difference (P>0.05). Conclusion The increasing RI of ICA, OA, CRA and PCA should be used as important indicators in the early diagnosis and judgment prognosis of NTG, and should also be referred to if the EDV numerical value of OA and CRA is decreased, to provide favorable information for judgment prognosis and treatment project of NTG patients.

Key words: Ultrasonic doppler,color, Glaucoma, Eye pressure

中图分类号: 

  • R775
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