山东大学耳鼻喉眼学报 ›› 2016, Vol. 30 ›› Issue (3): 32-36.doi: 10.6040/j.issn.1673-3770.0.2015.491

• 论著 • 上一篇    下一篇

咽喉部增生性病变相关发病因素分析

何桂军1,2,钱晓云1,顾亚军1,林川耀1,宋盼盼1,高下1   

  1. 1.南京医科大学鼓楼临床医学院耳鼻咽喉头颈外科, 江苏 南京 210000;
    2.连云港市第二人民医院耳鼻咽喉头颈外科, 江苏 连云港 222000
  • 收稿日期:2015-11-18 出版日期:2016-06-16 发布日期:2016-06-16
  • 通讯作者: 高下. E-mail:xiagaogao@hotmail.com E-mail:hgj2012000@163.co
  • 作者简介:何桂军. E-mail:hgj2012000@163.co
  • 基金资助:
    南京市医学科技发展项目(YYK14062)

Analysis of the risk factors of proliferative laryngopharyngeal disease.

HE Guijun1,2, QIAN Xiaoyun1, GU Yajun1, LIN Chuanyao1, SONG Panpan1, GAO Xia   

  1. 1. Department of Otolaryngology &Head and Neck Surgery, Drum Tower Clinical Medical College of Nanjing Medical University, Nanjing 210000, Jiangsu, China;2. Lianyungang Second Peoples Hospital, Lianyungang 222000, Jiangsu, China
  • Received:2015-11-18 Online:2016-06-16 Published:2016-06-16

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摘要： 目的 探讨影响咽喉部增生性病变发病的相关因素。 方法 收集门诊因咽喉部病变行电子喉镜检查及治疗的471例患者的一般情况、临床病理资料及反流症状指数(RSI)、反流体征评分(RFS)并进行统计学分析。 结果 吸烟、饮酒、RSI、RFS及胃病史与咽喉部是否出现增生性病变有相关性(P<0.05);而年龄、性别、体质量指数(BMI)与咽喉部是否出现增生性病变无明显相关性。年龄、性别、吸烟、饮酒及RFS与咽喉部增生性病变的性质有显著相关性(P<0.001);BMI与咽喉部增生性病变性质有相关性(P<0.05);RSI及胃病史则与之无关。Logistic回归分析发现,年龄、性别、吸烟、饮酒及RFS评分是咽喉部增生性病变的独立危险因素(P<0.05)。 结论 影响咽喉部是否出现增生性病变的主要因素是吸烟、饮酒、RSI、RFS及胃病史;增生物的良恶性则与年龄、性别、吸烟、饮酒、RFS及BMI相关。

关键词: 咽喉疾病, 反流症状指数(RSI), 反流体征评分(RFS), 病因

Abstract: Objective To investigate the risk factors of proliferative laryngopharyngeal disease(PLD). Methods A total of 471 patients with PLD were included in this retrospective study. Their general information, clinical data, reflux symptom index(RSI)and reflux fluiding score(RFS)were statistically analyzed. Results Smoking, alcohol, RSI, RFS and gastrosis were correlated with PLD(P<0.05), while age, sex and BMI were not correlated. Age, sex, smoking, alcohol and RFS score were significantly correlated with the nature of PLD(P<0.001), BMI was significantly correlated(P<0.05), while RSI score and gastrosis were not correlated. Logistic regression analysis indicated that age, gender, smoking, alcohol and RFS score were independent risk factors for the development of PLD(P<0.05). Conclusions The risk factors for PLD include smoking, alcohol, RSI, RFS and gastrosis. The benign or malignant nature of PLD is related to age, sex, smoking, alcohol, RFS and BMI.

Key words: Reverse fluid sign score, Etiology, Reflux symptom index, Pharyngolaryngeal disease

中图分类号: 

  • R739.65
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