JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY)

• Articles • Previous Articles     Next Articles

Innervation of the rat endolymphatic sac

TAN Jie，ZHANG Rong   

  1. Department of Otolaryngology & Head and Neck Surgery, Affiliated First Hospital of Fujian Medical University,Fujian Institute of Otolaryngology, Fuzhou 350005, Fujian, China
  • Received:2005-09-14 Revised:1900-01-01 Online:2006-12-24 Published:2006-12-24
  • Contact: TAN Jie

Abstract: The endolymphatic sac (ES) is a part of the homeostasisregulating system of the membranous labyrinth of the inner ear. Factors that influence blood flow in the sac may affect its function. This blood flow may be influenced by autonomic innervation; however，no such innervation has been demonstrated. The purpose of this study is to confirm the existence of the nerve fibres on the endolymphatic sac. Methods: Fifteen healthy Swards white rats were divided into three groups randomly. The temporal bones were taken out and were processed and sectioned by paraffinembedded technique. The sections of ES were stained by the antibody that was not labeled by biotin including the antibody for neurone specific enolase (NSE), antibody for glial fibrillary acidic protein (GFAP) and antibody for neurofilament (NF). The slides were observed by light microscope. Results： On light microscope, the brown positive staining was observed in the epithelia of ES. However，there was not any positive staining on the negative control slides. Conclusion: Nerve fibers exactly exist in the epithelia of ES.

Key words: Endolymphatic sac, Nerve fibers, Meniere's disease, Immunohistochemistry

[1] HUANG Qiao, REN Yi, HOU Tao, LIAO Xingwei, ZHU Zi’ang, ZHAN Xiaolin, LIU Ying, YIN Shihua. Expression of EphB2 in nasopharyngeal carcinoma tissues and its correlation with clinicopathological characteristics [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2025, 39(4): 26-30.
[2] LI Gui, YANG Yanli, LI Donghai, YAN Xiuying. Adult orbital xanthogranulomatous disease with clinicopathological analysis report and literature review [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(5): 80-85.
[3] LI Yaru, XU Zhenju, WANG Xiaojun, FU Tao, YUAN Yue, WU Ce. Rosai-Dorfman disease of the bilateral neck and nasopharynx: a case report and review of related cases [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(4): 108-114.
[4] WANG Jingsong, YU Can, ZHANG Xi, DENG Qicheng, XIE Zhuoliang, ZHAO Rui, WEN Bei, LIU Hai. Expression and clinical significance of KRT4 in laryngeal carcinoma and adjacent normal mucosal tissues [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(3): 12-17.
[5] YANG Kaiyan, TANG Fengzhu, QIN Qicai, LI Xuxiang, FENG Dayi, NONG Fengjing, YANG Qiuyun. Expression of abnormal spindle-like microcephaly associated protein in nasopharyngeal carcinoma and its clinical significance [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2024, 38(3): 18-25.
[6] HUANG Hengfeng, MA Kunpeng, YANG Di, ZHANG Lijun, ZHANG Shenglin. Expression and clinical significance of miR-181b-5P and EPB41L3 protein in laryngeal squamous cell carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(1): 41-46.
[7] XU Jia, LI Xin, CHEN Wenjing, GAO Juanjuan, LU Xingxing, YI Haijin. Short-term and long-term outcomes of endolymphatic sac decompression with instillation of local steroids for intractable Meniere's disease [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 17-21.
[8] HAN Shuhui, FAN Xintai, WANG Na, WANG Zhe, HOU Lingxiao, XU Anting. A study on the relationship between mastoid pneumatization degree and endolymphatic sac development based on a propensity score matching analysis [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(4): 22-26.
[9] CHENG Yao, ZHANG Zhen, YANG Ji, FENG Chengmin, DENG Qicheng, ZHANG Xi, ZHAO Rui, ZHU Xin, WU Junzhi, LIU Hai, DENG Shishan. Expression and clinical significance of CIP2A in hypopharyngeal carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(2): 40-44.
[10] YAN Chunxiao, JIN Lin, FANG Shifeng, WEI Yushan, WANG Lijing, CUI Lin, ZHAO Dan, MU Yanan,. Corneal nerve fiber regeneration after SPT-TPRK combined with 0.02% MMC for moderate myopia: a random control study [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(6): 25-32.
[11] XUE Gang, SUN Xinmin, LIN Xu, WU Jingfang. Expression and clinical significance of the KCNK5 double-pore potassium channel protein in papillary thyroid carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(4): 64-69.
[12] . Expression of cyclin E2 in hypopharyngeal cancer and its clinical significance [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2020, 34(5): 132-137.
[13] JIANG Ningning, WANG Penglai, YUAN Changyong, HUANG Xiaofeng, JIANG Changwei, LIU Zongxiang,SUN Tiezhong. The expression and significance of metastasis suppressor 1 protein in tongue squamous cell carcinoma [J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(6): 64-67.
[14] LI Hao, LI Yanzhong, WANG Yan. Hypoxia inducible factor-1 alpha and vascular endothelial growth factor expression in the soft palate of [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2018, 32(2): 43-47.
[15] ZHANG Menglu, LI Yongtuan.. Expression of chemokine ligand 27 in secondary middle ear cholesteatoma. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(6): 46-48.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd