Abstract: To evaluate the effect of functional endoscopic sinus surgery and the modus operandi on symptoms and quality of life of patients with chronic rhinosinusitis. Methods Sixty patients with chronic rhinosinusitis and nasal polyps were enrolled by random and their QOL scores were assessed by using QOL instruments including existing SF-36 questionnaires (Chinese version) and SNOT-20 questionnaires, and of them patients of different groups were given different scope surgeries to appraise the impact of the modus operandi on patient′s symptoms and the quality of life. ResultsIn the 1 month follow-up settings, such domains as role physical， mental health, role emotional and general health of SF-36, scores of the total 20 items and the most important 5-item scores of SNOT-20 were markedly improved (P＜0．05)； in the 2-6 month follow-up settings， the above indexes stayed fixed(P＞0．05)； and in the 6month follow-up settings， indexes of symptoms and QOL status entirely improved from the baseline，and different scope surgeries had no statistical significance on symptoms and QO L. ConclusionsOn the whole patients undergoing endoscopic sinus surgery have their symptoms relieved and QOL status will be normal on postoperative 6 months. Improved and traditional endoscopic sinus surgery are basically identical on the improvement of the symptoms and QOL.

Key words: Sinusitis, Nasal polyps, Quality of life, Endoscopy, SF-36, SNOT-20, Surgical procedures