Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2020, Vol. 34 ›› Issue (3): 129-133.doi: 10.6040/j.issn.1673-3770.0.2019.501

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Applications of CO2 laser microsurgery on laryngeal precancerous lesions and early glottic laryngeal carcinoma

XU Jinjing, HU Jinghua, WU Yuanqing, DENG Yi, YU Weiwei   

  1. Department of Otolaryngology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu, China
  • Published:2020-06-29

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Abstract: Objective This study aimed to investigate the clinical applications of CO2 laser microsurgery for laryngeal precancerous lesions and early glottic laryngeal cancer. Methods A total of 27 patients, nine diagnosed with laryngeal precancerous lesions and 18 with early glottic laryngeal cancer, who had undergone CO2 laser microsurgery were selected from January 2014 to August 2018 from the otolaryngology department of the Nanjing First Hospital(Nanjing Medical University). We observed the postoperative complications, the before and after surgery quality of life, and the postoperative 1~2-year local recurrence rate and evaluated the therapeutic effects of CO2 laser microsurgery. Results Patients were classified into two groups depending on the scope and depth of CO2 laser microsurgical resection. In the precancerous lesions group, eight patients received a type I operation and one patient received a type II operation. In the glottic laryngeal cancer group, three patients received a type II operation, 11 patients received a type III operation, three patients received a type IV operation, and one patient received a type V operation. One patient underwent open surgery because the surgical margin was positive. None of the other patients underwent tracheotomy, and no serious complications such as airway burns were noted. The patients were offered soft food six hours after surgery; no adverse reactions such as choking or dyspnea were observed. Further, the patients received anti-infective and anti-inflammatory treatment for 2-3 days after surgery. The patients were followed up for 1~2 years postoperatively. The voices of the patients recovered after the operation. Conclusion CO2 laser laryngeal microsurgery has significant clinical applications in the treatment of laryngeal precancerous lesions and early glottic laryngeal carcinoma, leading to increased safety, less trauma, faster voice recovery, and shorter hospitalization times, in turn leading to larynx function preservation and improvements in the postoperative quality of life.

Key words: CO2 laser laryngeal microsurgery, Laryngeal precancerous lesions, Early glottic laryngeal carcinoma, Suspension laryngoscope, Prognosis

CLC Number: 

  • R767
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