鼻腔鼻窦神经鞘瘤13例临床分析

doi:10.6040/j.issn.1673-3770.0.2022.229

摘要/Abstract

摘要： 目的探讨鼻腔鼻窦神经鞘瘤的临床特征,以提高对该病的认识及诊疗水平。方法回顾性分析2012~2021年间郑州大学第一附属医院收治的13例鼻腔鼻窦神经鞘瘤患者的临床病例资料。结果 13例患者中女10例、男3例。恶性1例,良性12例,13例均行手术治疗,1例恶性神经鞘瘤患者术后辅助放疗。术后随访4~110个月,12例良性患者均未复发,1例恶性患者死于复发。结论发生于鼻腔鼻窦的神经鞘瘤以良性为主,临床表现无特异性,单侧鼻塞和头痛最多见,鼻腔及筛窦为最常见发病部位。术前的影像学检查能较好显示肿瘤侵犯范围,指导手术方式。主要治疗手段为彻底手术切除,恶性者术后容易复发,需要辅助放疗。

关键词: 神经鞘瘤, 鼻腔鼻窦, 诊断, 治疗, 预后

Abstract: Objective Neurilemmomas in the nasal cavity or paranasal sinuses are rare. This study aimed to improve our understanding of this phenomenon by exploring the clinical features, diagnosis, and management of neurilemmomas in the nasal cavity or paranasal sinuses. Methods Clinical records of all patients with neurilemmomas in the nasal cavity or paranasal sinuses treated at our hospital between 2012 and 2021 were retrospectively reviewed. Results Ten female and three male patients were included. One case was malignant and twelve were benign. All patients underwent surgery, and the patient with malignancy received postoperative radiotherapy. The follow-up duration of the study was 4-110 months, and the clinical follow-up data revealed no recurrences in the 12 benign cases; however, the patient with malignancy died of recurrence. Conclusion Neurilemmomas in the nasal cavity and paranasal sinuses are typically benign, with no specific clinical manifestations. In our study, the most common complaints were unilateral nasal congestion and headaches, and the most common sites were the nasal cavity and ethmoid sinus. Imaging examination is valuable in identifying the range of the lesions and in diagnosing benign and malignant tumors. Complete surgical excision using the appropriate approaches has been demonstrated to be effective, with a low recurrence rate, whereas postoperative radiotherapy is necessary for malignant cases because the risk of relapse is high.

Key words: Neurilemmoma, Nasal cavity and paranasal sinus, Diagnosis, Therapy, Prognosis

中图分类号:

R765.9

韩飞燕,王英. 鼻腔鼻窦神经鞘瘤13例临床分析[J]. 山东大学耳鼻喉眼学报, 2023, 37(2): 21-25.

HAN Feiyan, WANG Ying. Clinical analysis of 13 cases of neurilemmomas in the nasal cavity and paranasal sinuses[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(2): 21-25.

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