山东大学耳鼻喉眼学报 ›› 2023, Vol. 37 ›› Issue (5): 31-41.doi: 10.6040/j.issn.1673-3770.0.2022.401

• 论著 • 上一篇    下一篇

利用百度指数分析中国过敏性鼻炎及相关变应性疾病的流行特征

王剑,杜伟嘉,薛涛,陈福权   

  1. 中国人民解放军空军军医大学附属第一医院 耳鼻咽喉头颈外科, 陕西 西安 710032
  • 发布日期:2023-10-13
  • 通讯作者: 陈福权. E-mail:chenfq@fmmu.edu.cn
  • 基金资助:
    陕西省重点产业创新链项目(2021ZDLSF02-12)

Analysis of the epidemic characteristics of allergic rhinitis and related allergic diseases in China using Baidu index data

WANG Jian, DU Weijia, XUE Tao, CHEN Fuquan   

  1. Department of Otorhinolaryngology & Head and Neck Surgery, the First Affiliated Hospital of Air Force Medical University of PLA, Xi'an 710032, Shaanxi, China
  • Published:2023-10-13

摘要: 目的 分析百度指数平台中过敏性鼻炎(AR)在中国各地区的流行时间特征、相关变应性疾病与AR的时空相关性。 方法 在百度指数平台以“过敏性鼻炎”检索并提取我国2011年1月至2022年6月的检索数据,分析AR及相关变应性疾病搜索量的时间和空间分布特征,探究AR搜索量与相关变应性疾病搜索量的相关性。 结果 全国AR搜索量呈明显的季节性变化。第一个峰值出现在4~6月间,第二个更高的峰值出现在8~10月间。北方地区过敏季较短,多集中在春秋两季;南方地区过敏季较长,往往从春季持续至秋季。地域方面分析,北方地区表现为双尖峰型,西部地区表现为单主峰型,长江流域表现为双主峰型,而东南地区多表现为宽峰型。全国整体分析,AR搜索量与相关变应性疾病(“过敏性结膜炎” “过敏性咳嗽” “过敏性哮喘”“过敏性荨麻疹”)搜索量呈正相关(R分别为0.4000.3540.3960.346,P<0.001);“过敏性结膜炎搜索量与过敏性哮喘搜索量呈正相关(R=0.685,P<0.001);“过敏性结膜炎搜索量与过敏性咳嗽搜索量(R=-0.327,P<0.001),以及过敏性哮喘搜索量与过敏性荨麻疹搜索量(R=-0.200,P<0.05)均呈负相关。而北京、上海与广州的AR搜索量与相关变应性疾病搜索量相关关系与全国的相关关系不尽相同。 结论 AR及相关变应性疾病检索词的搜索量在国内不同地区呈现不同趋势,与AR的国内流行病学特征相符,应结合地区特点针对性开展线上及线下的变应性疾病的科普与预防宣教。

关键词: 过敏性鼻炎, 百度指数, 流行病学, 过敏性结膜炎

Abstract: Objective To analyze the epidemic characteristics of allergic rhinitis(AR)in various areas of China by means of the Baidu Index website data, and to analyze the possible temporal and spatial correlations between AR and related allergic diseases. Methods On the Baidu Index website, AR was used as the key search word to extract data of Chinese from January 2011 to June 2022. The temporal and spatial data characteristics of AR and related allergic diseases were analyzed, and the correlations between AR and related allergic diseases were explored. Results The extracted volume of AR in China shows obvious seasonal variations. The first peak appears from April to June, and the second, higher peak, appears from August to October. The allergy season of AR in the northern provinces is short and mostly concentrated in the Spring and Autumn. The southern provinces have a long allergy season, which usually lasts from Spring to Autumn. Geographically, the northern region exhibits double sharp peaks, the western region has single peaks, the Yangtze River basin is associated with double peaks, and the southeast region manifests with wide peaks. On the whole, the extracted volume of AR was positively correlated with the volume for related allergic diseases("allergic conjunctivitis", "allergic cough", "allergic asthma" and "allergic urticaria")(R values were 0.400, 0.354, 0.396, 0.346, respectively, all P<0.001); The extracted volume of "allergic conjunctivitis" was positively correlated with that of "allergic asthma"(R=0.685, P<0.01). The volume of allergic conjunctivitis and allergic cough(R=-0.327, P<0.01), and the volume of allergic asthma and allergic urticaria(R=-0.200, P<0.05)were negatively correlated. The correlations between the extracted volume of AR and related allergic diseases in Beijing, Shanghai and Guangzhou were not the same as those in the whole country. Conclusion The search volume of AR and related allergic diseases showed different trends in different regions of China, which is consistent with the domestic epidemiological characteristics of AR. It is recommended online and offline popular science and preventive education for allergic diseases should be carried out in accordance with the characteristics of each region.

Key words: Allergic rhinitis, Baidu index, Epidemiology, Allergic conjunctivitis

中图分类号: 

  • R765.21
[1] 倪璟滋, 万文锦, 程雷. 变应性鼻炎健康相关生活质量研究进展[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 110-115, 122 NI Jingzi, WAN Wenjin, CHENG Lei. Research progress on health-related quality of life in allergic rhinitis[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2022, 36(3): 110-115, 122
[2] 中华耳鼻咽喉头颈外科杂志编辑委员会鼻科组, 中华医学会耳鼻咽喉头颈外科学分会鼻科学组、小儿学组. 儿童变应性鼻炎诊断和治疗指南(2022年,修订版)[J]. 中华耳鼻咽喉头颈外科杂志, 2022, 57(4): 392-404. doi:10.3760/cma.j.cn115330-20220303-00092
[3] 中华耳鼻咽喉头颈外科杂志编辑委员会鼻科组, 中华医学会耳鼻咽喉头颈外科学分会鼻科学组. 中国变应性鼻炎诊断和治疗指南(2022年,修订版)[J]. 中华耳鼻咽喉头颈外科杂志, 2022, 57(2): 24. doi: 10.3760/cma.j.cn115330-20211228-00828
[4] 祝戎飞, 刘争. 变应性鼻炎的分级预防[J]. 中华耳鼻咽喉头颈外科杂志, 2022, 57(4): 379-384. doi: 10.3760/cma.j.cn115330-20210618-00358 ZHU Rongfei, LIU Zheng. Graded prevention of allergic rhinitis[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2022, 57(4): 379-384. doi: 10.3760/cma.j.cn115330-20210618-00358
[5] Zhang Y, Zhang L. Increasing prevalence of allergic rhinitis in China[J]. Allergy Asthma Immunol Res, 2019, 11(2): 156-169. doi:10.4168/aair.2019.11.2.156
[6] 王学艳, 祁海, 张罗. 从全球变应性鼻炎流行趋势看加强变应性鼻炎防治的中国行动[J]. 中华耳鼻咽喉头颈外科杂志, 2022, 57(4): 373-378.doi: 10.3760/cma.j.cn115330-20210927-00637 WANG Xueyan, QI Hai, ZHANG Luo. Perspectives for prevention and treatment of allergic rhinitis in China[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2022, 57(4): 373-378.doi: 10.3760/cma.j.cn115330-20210927-00637
[7] 杨钦泰. 大数据人工智能时代中国变应性鼻炎真实世界的研究与思考[J]. 中国中西医结合耳鼻咽喉科杂志, 2021, 29(3): 163-166. doi:10.16542/j.cnki.issn.1007-4856.2021.03.002 YANG Qintai. Research and thinking on the real world of allergic rhinitis in China in the age of big data and artificial intelligence[J]. Chinese Journal of Otorhinolaryngology in Integrative Medicine, 2021, 29(3): 163-166. doi:10.16542/j.cnki.issn.1007-4856.2021.03.002
[8] Bousquet J, Agache I, Anto JM, et al. Google Trends terms reporting rhinitis and related topics differ in European countries[J]. Allergy, 2017, 72(8): 1261-1266. doi:10.1111/all.13137
[9] 郭海丽, 张翔. 基于百度搜索指数的最大主成分方法监测流感[J]. 电子技术与软件工程, 2022(8): 231-234 GUO Haili, ZHANG Xiang. The maximum principal component method based on Baidu search index to monitor influenza[J]. Electronic Technology & Software Engineering, 2022(8): 231-234
[10] 董晓春, 李琳, 徐文体, 等. 特定关键词及百度指数与流感病毒活动相关性分析[J]. 中国公共卫生, 2016, 32(11): 1543-1546. doi:10.11847/zgggws2016-32-11-25 DONG Xiaochun, LI Lin, XU Wenti, et al. Correlation between Baidu index of specific keywords and influenaz epidemics[J]. Chinese Journal of Public Health, 2016, 32(11): 1543-1546. doi:10.11847/zgggws2016-32-11-25
[11] 林枫, 庞冲, 谷庆隆. 基于百度指数的北京地区儿童过敏性鼻炎关注度研究[J]. 中国实用儿科杂志, 2021, 36(2): 130-135. doi:10.19538/j.ek2021020611 LIN Feng, PANG Chong, GU Qinglong. Study on the attention of children with allergic rhinitis in Beijing based on Baidu index[J]. Chinese Journal of Practical Pediatrics, 2021, 36(2): 130-135. doi:10.19538/j.ek2021020611
[12] 曹玉洁, 徐睿, 陶逍遥, 等. 基于百度指数分析中国变应性鼻炎流行的时空特征[J]. 中华耳鼻咽喉头颈外科杂志, 2019, 54(12): 888-893. doi: 10.3760/cma.j.issn.1673-0860.2019.12.002 CAO Yujie, XU Rui, TAO Xiaoyao, et al. Investigation of temporal and spatial characteristics of allergic rhinitis epidemics by Baidu Index in China[J]. Chinese Journal of Otorhinolaryngology Head and Neck Surgery, 2019, 54(12): 888-893. doi: 10.3760/cma.j.issn.1673-0860.2019.12.002
[13] 聂凯, 王晓艳, 马可嘉, 等. 基于谷歌趋势与百度和微信指数的中国炎症性肠病概况研究[J]. 中华消化杂志, 2022, 42(6): 395-401.doi: 10.3760/cma.j.cn311367-20211127-00644 NIE Kai, WANG Xiaoyan, MA Kejia, et al. A survey of inflammatory bowel disease in China based on the Google Trends, Baidu index and WeChat index[J]. Chinese Journal of Digestion, 2022, 42(6): 395-401.doi: 10.3760/cma.j.cn311367-20211127-00644
[14] Higgins TS, Wu AW, Sharma D, et al. Correlations of online search engine trends with coronavirus disease(COVID-19)incidence: infodemiology study[J]. JMIR Public Health Surveill, 2020, 6(2): e19702. doi:10.2196/19702
[15] 杨倩. 基于百度指数的疫情相关健康信息搜索行为分析与信息服务策略[J]. 中华医学图书情报杂志, 2020, 29(6): 28-34. doi:10.3969/j.issn.1671-3982.2020.06.005 YANG Qian. Baidu index-based analysis of epidemic-related health information search behaviors and information service strategies[J]. Chinese Journal of Medical Library and Information Science, 2020, 29(6): 28-34. doi:10.3969/j.issn.1671-3982.2020.06.005
[16] 马赟, 邱泽恒, 梁茂金, 等. 变应性鼻炎与咽鼓管功能障碍:从百度指数到相关症状的研究[J]. 中国耳鼻咽喉头颈外科, 2022, 29(2): 111-114. doi:10.16066/j.1672-7002.2022.02.011 MA Yun, QIU Zeheng, LIANG Maojin, et al. Eustachian tube dysfunction in allergic rhinitis: from Baidu index to related symptoms[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2022, 29(2): 111-114. doi:10.16066/j.1672-7002.2022.02.011
[17] Bousquet J, Agache I, Berger U, et al. Differences in reporting the ragweed pollen season using google trends across 15 countries[J]. Int Arch Allergy Immunol, 2018, 176(3/4): 181-188. doi:10.1159/000488391
[18] 邵英, 杨永芳, 秦明芳, 等. 云南省18岁及以上人群过敏性疾病的流行现状调查[J]. 现代预防医学, 2020, 47(14): 2501-2504, 2520 SHAO Ying, YANG Yongfang, QIN Mingfang, et al. Prevalence and characteristics of anaphylaxis in adults in Yunnan Province[J]. Modern Preventive Medicine, 2020, 47(14): 2501-2504, 2520
[19] 刘全, 蔡国遇, 柳晓进, 等. 西藏日喀则地区变应性鼻炎患者变应原检测分析[J]. 临床耳鼻咽喉头颈外科杂志, 2020, 34(4): 311-313. doi:10.13201/j.issn.2096-7993.2020.04.006 LIU Quan, CAI Guoyu, LIU Xiaojin, et al. Allergens analysis in patients with allergic rhinitis in Rikaze[J]. Journal of Clinical Otorhinolaryngology Head and Neck Surgery, 2020, 34(4): 311-313. doi:10.13201/j.issn.2096-7993.2020.04.006
[20] 王玮豪, 孔维封, 郑瑞, 等. 广州地区不同性别变应性鼻炎吸入性及食入性变应原谱特征分析[J]. 中山大学学报(医学科学版), 2022, 43(1): 10-17. doi:10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0102 WANG Weihao, KONG Weifeng, ZHENG Rui, et al. Pattern of inhalant and food allergens in patients with allergic rhinitis by gender in Guangzhou[J]. Journal of Sun Yat-sen University(Medical Sciences), 2022, 43(1): 10-17. doi:10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).2022.0102
[21] 刘琢扶, 卢涵宇, 冯仙, 等. 上海地区变应性鼻炎过敏原皮肤点刺结果分析[J]. 中国眼耳鼻喉科杂志, 2021, 21(5): 345-349. doi:10.14166/j.issn.1671-2420.2021.05.007 LIU Zhuofu, LU Hanyu, FENG Xian, et al. Analysis of skin prick test results of allergens in allergic rhinitis in Shanghai[J]. Chinese Journal of Ophthalmology and Otorhinolaryngology, 2021, 21(5): 345-349. doi:10.14166/j.issn.1671-2420.2021.05.007
[22] 秦晓燕, 郭广宏, 康慧媛, 等. 北京地区变应性鼻炎患者血清总IgE及sIgE结果分析[J]. 标记免疫分析与临床, 2020, 27(5): 741-745. doi:10.11748/bjmy.issn.1006-1703.2020.05.006 QIN Xiaoyan, GUO Guanghong, KANG Huiyuan, et al. An analysis of serum total IgE and sIgE results in patients with allergic rhinitis in Beijing area[J]. Labeled Immunoassays and Clinical Medicine, 2020, 27(5): 741-745. doi:10.11748/bjmy.issn.1006-1703.2020.05.006
[23] 刘杰, 曲辉, 鹿道温, 等. 青岛市西部城区春季花粉症调查分析[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 70-72, 78. doi:10.6040/j.issn.1673-3770.0.2017.274 LIU Jie, QU Hui, LU Daowen, et al. Spring pollinosis in Qingdao west district[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(2): 70-72, 78. doi:10.6040/j.issn.1673-3770.0.2017.274
[24] 洪海裕, 许光福, 杨烁伟, 等. 探究广东地区变应性鼻炎合并支气管哮喘的危险因素[J]. 山东大学耳鼻喉眼学报, 2019, 33(1): 94-98. doi:10.6040/j.issn.1673-3770.1.2018.038 HONG Haiyu, XU Guangfu, YANG Shuowei, et al. The prevalence and risk factors of bronchial asthma in patients with allergic rhinitis in Guangdong Province[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2019, 33(1): 94-98. doi:10.6040/j.issn.1673-3770.1.2018.038
[25] Konstantinou GN, Konstantinou GN, Koulias C, et al. Further understanding of neuro-immune interactions in allergy: implications in pathophysiology and role in disease progression[J]. J Asthma Allergy, 2022, 15: 1273-1291. doi:10.2147/JAA.S282039
[26] 邓卓怡, 刘晓佳, 高子奇, 等. 内蒙古自治区变应性鼻炎高发城市气传花粉及相关因素[J]. 中华临床免疫和变态反应杂志, 2021, 15(6): 618-624. doi:10.3969/j.issn.1673-8705.2021.06.004 DENG Zhuoyi, LIU Xiaojia, GAO Ziqi, et al. Analysis of airborne pollens and related factors among cities with high incidence of aller? gic rhinitis in Inner Mongolia[J]. Chinese Journal of Allergy & Clinical Immunology, 2021, 15(6): 618-624. doi:10.3969/j.issn.1673-8705.2021.06.004
[27] 杨晴, 陆美萍, 程雷. 苏皖地区变应性鼻炎患者气传变应原皮肤点刺试验和血清特异性IgE检测的一致性及相关性分析[J]. 山东大学耳鼻喉眼学报, 2021, 35(1): 40-46. doi:10.6040/j.issn.1673-3770.0.2020.279 YANG Qing, LU Meiping, CHENG Lei. Agreement and association analyses of skin prick testing and serum specific IgE assay for aeroallergen detection in patients with allergic rhinitis from Jiangsu and Anhui areas[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2021, 35(1): 40-46. doi:10.6040/j.issn.1673-3770.0.2020.279
[28] Pereira MP, Ziehfreund S, Rueth M, et al. Google search trends for itch in Europe: a retrospective longitudinal study[J]. J Eur Acad Dermatol Venereol, 2021, 35(6): 1362-1370. doi:10.1111/jdv.17077
[29] 黄婕, 刘慧, 刘维斯, 等. 基于百度指数的我国新型冠状病毒肺炎网络舆情分析[J]. 预防医学情报杂志, 2022, 38(2): 172-177 HUANG Jie, LIU Hui, LIU Weisi, et al. Network public sentiment analysis of COVID-19 based on Baidu Index in China[J]. Journal of Preventive Medicine Information, 2022, 38(2): 172-177
[1] 毕晓云,马本绪,王心茹,李旭豪,杨继国. 穴位贴敷治疗小儿过敏性鼻炎随机对照试验的Meta分析[J]. 山东大学耳鼻喉眼学报, 2023, 37(4): 75-85.
[2] 王惟一,时蕾,张志玉,张贵玲,时光刚. 高脂饮食对过敏性鼻炎小鼠致敏影响和肠道菌群改变的研究[J]. 山东大学耳鼻喉眼学报, 2023, 37(3): 21-29.
[3] 姜超,周炫辰,韩杰,岳志勇. IVc期下咽癌特征分析及列线图预后模型构建[J]. 山东大学耳鼻喉眼学报, 2022, 36(4): 49-54.
[4] 张雅琪,刘慧敏,曹淋曼,王子钰,林旭,李燕萍,薛刚,吴靖芳. MAPK、PI3K-AKT、NF-κB在小鼠过敏性鼻炎中的表达及意义[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 254-259.
[5] 庞冲,边赛男,张冰,尹旭,陆颖霞,叶鹏飞,王湛,赵晶,高彦,关凯. 儿童过敏性鼻炎粉尘螨特异性舌下免疫治疗短期疗效评估[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 70-74.
[6] 王鑫,刘巧平,闫占峰,刘思溟,朱雅静,丁倩,张莹,田媛,张京然. 基于网络药理学探究小青龙汤治疗过敏性鼻炎的作用机制[J]. 山东大学耳鼻喉眼学报, 2021, 35(5): 46-55.
[7] 王宇婷,王嘉玺. microRNA在过敏性鼻炎发病机制中的研究进展[J]. 山东大学耳鼻喉眼学报, 2021, 35(5): 98-104.
[8] 李化静,郝润梅,戴皓,张令,申震,权芳,邵渊. 儿茶素抑制卵清蛋白诱导的过敏性鼻炎小鼠模型炎症反应的机制研究[J]. 山东大学耳鼻喉眼学报, 2021, 35(4): 1-7.
[9] 林兴,沈翎,林宗通,杨中婕. 儿童鼻腔异物与过敏性鼻炎关系的初步研究[J]. 山东大学耳鼻喉眼学报, 2020, 34(4): 101-104.
[10] 徐海侠,崔晓波,刘佳荣,李欣,刘佳宜,刘晓玲. 内蒙古呼和浩特城区气传致敏花粉流行情况调查[J]. 山东大学耳鼻喉眼学报, 2020, 34(2): 106-109.
[11] 邱昌余,周俊,庄德恩,杨晴,陆美萍,程雷. 人工智能技术在辅助耳鼻咽喉科医师了解过敏性鼻炎患者需求中的应用[J]. 山东大学耳鼻喉眼学报, 2019, 33(3): 88-94.
[12] 秦雅楠,王琳,姜彦,闫舒,陈敏,于龙刚,李娜. 2008~2017年青岛地区变应性鼻炎常见吸入性变应原分布[J]. 山东大学耳鼻喉眼学报, 2019, 33(1): 67-72.
[13] 梁小红,李艳,彭万达,宗赟, 李翀. 阻塞性睡眠呼吸暂停与肿瘤的研究进展[J]. 山东大学耳鼻喉眼学报, 2017, 31(1): 70-74.
[14] 王岩. 儿童睡眠呼吸疾病的分类与治疗进展[J]. 山东大学耳鼻喉眼学报, 2016, 30(5): 5-8.
[15] 高荣莉1,丁见2,臧延伟3,闫舒1,刘婷婷1,刘赞刚4,宫相贵5,周晓彬6,李娜1,张念凯1. 青岛地区变应性鼻炎流行病学调查研究[J]. 山东大学耳鼻喉眼学报, 2012, 26(2): 55-60.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!