山东大学耳鼻喉眼学报 ›› 2015, Vol. 29 ›› Issue (5): 62-64.doi: 10.6040/j.issn.1673-3770.0.2015.167

• 论著 • 上一篇    下一篇

南京地区急性细菌性结膜炎的最新致病菌分析

赵太宏, 李中国   

  1. 南京医科大学附属南京医院 南京市第一医院眼科, 江苏 南京 210006
  • 收稿日期:2015-04-23 修回日期:2015-09-22 出版日期:2015-10-16 发布日期:2015-10-16
  • 作者简介:赵太宏,E-mail:zhao.eye@163.com

Pathogens of acute bacterial conjunctivitis in Nanjing area

ZHAO Taihong, LI Zhongguo   

  1. Department of Ophthalmology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu, China
  • Received:2015-04-23 Revised:2015-09-22 Online:2015-10-16 Published:2015-10-16

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摘要： 目的 了解南京地区急性细菌性结膜炎的致病菌分布情况,为有效治疗本病提供参考。方法 选取符合纳入标准的96眼急性细菌性结膜炎的结膜囊分泌物进行病原学检测,同时予以加替沙星滴眼液滴眼,每日4次,连续治疗1周,再次取分泌物进行病原学检查,并进行对比分析。结果 86眼均成功采集结膜囊分泌物。首次病原学检测阳性率为81.25%,其中革兰阴性细菌占15.63%,以大肠埃希菌及肺炎克雷伯菌为主;而革兰阳性细菌占65.63%,其中位居前三的分别为表皮葡萄球菌50眼(52.08%),金黄色葡萄球菌7眼(7.29%),腐生葡萄球菌3眼(3.13%)。治疗1周后,患者临床症状均治愈,再次行病原学检查,仍有11眼阳性,表皮葡萄球菌7眼(8.14%),金黄色葡萄球菌4眼(4.65%),67眼(77.92%)转为阴性。结论 葡萄球菌尤其以表皮葡萄球菌为主是南京地区急性细菌性结膜炎的主要致病菌,临床治疗本病应注意合理用药。

关键词: 细菌性结膜炎, 急性, 病原学检测

Abstract: Objective To investigate the pathogenic bacteria of acute bacterial conjunctivitis in Nanjing area and to provide reference for treatment. Methods Ninety-six eyes with acute bacterial conjunctivitis were enrolled in this study. Bacterial culture was performed on secretion specimens from conjunctival sac. Meanwhile, treatment with Gatifloxacin eye drops(4 times per day, 1 week) was carried out. After treatment, secretion specimens were re-cultivated. Results Secretion specimens of 86 eyes were successfully collected and cultivated two times. The positive rate was 81.25% in the first time. The percentages of gram positive bacteria (the top three: Staphylococcus epidermidis 52.08%, Staphylococcus aureus 7.29% and Staphylococcus saprophyticus 3.13%) and Gram negative bacteria (Escherichia coli and Klebsiella pneumoniae) in the bacteria were 65.63% and 15.63% respectively. No eye symptoms were observed after the treatment. For the second cultivation, 67 eyes(77.92%) turned to negative, 7 eyes(8.14%) were with Staphylococcus epidermidis and 4 eyes(4.65%) with Staphylococcus aureus. Conclusion The main pathogenic bacterium in acute bacterial conjunctivitis in Nanjing Area is Staphylococcus epidermidis, which should be paid attention in clinical treatment.

Key words: Acute, Bacterial conjunctivitis, Etiology detection

中图分类号: 

  • R77
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