山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (4): 125-129.doi: 10.6040/j.issn.1673-3770.0.2019.355

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变应性鼻炎中信号传导通路的研究进展

黄嘉莉1综述杨淑荣2审校   

  1. 黄嘉莉1 综述杨淑荣2 审校1.江西中医药大学临床医学院, 江西 南昌 3300002.江西中医药大学附属医院 耳鼻喉科, 江西 南昌 330000
  • 收稿日期:2019-07-15 出版日期:2020-07-20 发布日期:2020-08-28
  • 基金资助:
    江西中医药大学校级研究生创新专项资金项目(JZYC18S31)

Advances in research on related signaling pathways in allergic rhinitisHUANG Jiali1 Review YANG Shurong2〓Guidance 1.Department of Clinical Medicine, Jiangxi University of Traditional Chinese Medicine,Nanchang 330000, Jiangxi, China 2.Department of Otolaryngology, Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330000, Jiangxi, ChinaAbstract:

The occurrence and development of allergic rhinitis involves a variety of signal transduction pathways. Studying signal transduction pathways can promote the progress of pathogenesis research, suggesting that we can block the conduction of pathways in a pathway to achieve therapeutic effects. Open up new prospects for designing and developing more effective new drug treatments.The common signaling pathways in allergic rhinitis are reviewed in this article to provide a reference for the treatment of allergic rhinitis.   

  1. Key words: Allergic rhinitis;
    Signal transduction;
    Pathway;
    Nosogenesis 变应性鼻炎(allergic rhinitis, AR)是变态反应性疾病中最常见的上呼吸道疾病, 从西方发达国家已有的数据来看, 未来随着人民生活环境清洁度的提高, AR的发病率也会呈上升趋势［1-2］。信号转导是变应性疾病发病机制研究的一大热点, 近年来关于变应性疾病中信号传导通路的研究日益增多, 对各信号通路的发病机制的研究, 有助于寻找到有效的干预途径, 达到预防与治疗AR的目的。
  • Received:2019-07-15 Online:2020-07-20 Published:2020-08-28

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摘要： 变应性鼻炎发生及发展的过程涉及多种信号传导通路,研究信号传导通路可以推动发病机制的研究进展,提示应用某一通路中的阻断剂阻断通路传导以达到治疗作用,为设计开发更有效新型药物治疗开拓新的前景。综述变应性鼻炎中常见的信号传导通路,为治疗变应性鼻炎提供参考。

关键词: 变应性鼻炎, 信号转导, 通路, 发病机制

Abstract: The occurrence and development of allergic rhinitis involves a variety of signal transduction pathways. Studying signal transduction pathways can promote the progress of pathogenesis research, suggesting that we can block the conduction of pathways in a pathway to achieve therapeutic effects. Open up new prospects for designing and developing more effective new drug treatments.The common signaling pathways in allergic rhinitis are reviewed in this article to provide a reference for the treatment of allergic rhinitis.

Key words: Allergic rhinitis, Signal transduction, Pathway, Nosogenesis

中图分类号: 

  • R765
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