山东大学耳鼻喉眼学报 ›› 2021, Vol. 35 ›› Issue (2): 119-124.doi: 10.6040/j.issn.1673-3770.0.2020.187
张一彤,刘海琴综述任晓勇审校
ZHANG Yitong, LIU HaiqinOverview,REN XiaoyongGuidance
摘要: 近年来儿童阻塞性睡眠呼吸暂停(OSA)发病率呈逐年上升趋势,由于儿童正处于生长发育期,OSA所致的睡眠碎片化和间歇性低氧血症将严重损害神经认知功能等,对儿童的健康成长造成极大的危害。儿童OSA在发病原因、诊断标准及相关检查等方面与成人相比差异较大,其对认知功能的影响更是存在一定争议。因此,论文通过对近年儿童OSA及其认知功能影响的相关性研究进行回顾,并对其未来发展趋势做出展望。
中图分类号:
[1] 王岩. 儿童睡眠呼吸疾病的分类与治疗进展[J]. 山东大学耳鼻喉眼学报, 2016, 30(5): 5-8. doi: 10.6040/j.issn.1673-3770.0.2016.405. WANG Yan. Progress in the classification and treatment of sleep respiratory diseases in children[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2016, 30(5): 5-8. doi: 10.6040/j.issn.1673-3770.0.2016.405. [2] Blunden SL, Beebe DW. The contribution of intermittent hypoxia, sleep debt and sleep disruption to daytime performance deficits in children: consideration of respiratory and non-respiratory sleep disorders[J]. Sleep Med Rev, 2006, 10(2): 109-118. doi:10.1016/j.smrv.2005.11.003. [3] Dayyat E, Kheirandish-Gozal L, Sans Capdevila O, et al. Obstructive sleep apnea in children: relative contributions of body mass index and adenotonsillar hypertrophy[J]. Chest, 2009, 136(1): 137-144. doi:10.1378/chest.08-2568. [4] Spruyt K, Sans Capdevila O, Serpero LD, et al. Dietary and physical activity patterns in children with obstructive sleep apnea[J]. J Pediatr, 2010, 156(5): 724-730, 730.e1-730.e3. doi:10.1016/j.jpeds.2009.11.010. [5] Halbower AC, Degaonkar M, Barker PB, et al. Childhood obstructive sleep apnea associates with neuropsychological deficits and neuronal brain injury[J]. PLoS Med, 2006, 3(8): e301. doi:10.1371/journal.pmed.0030301. [6] Devita M, Montemurro S, Ramponi S, et al. Obstructive sleep apnea and its controversial effects on cognition[J]. J Clin Exp Neuropsychol, 2017, 39(7): 659-669. doi:10.1080/13803395.2016.1253668. [7] da Silva Gusmão Cardoso T, Pompéia S, Miranda MC. Cognitive and behavioral effects of obstructive sleep apnea syndrome in children: a systematic literature review[J]. Sleep Med, 2018, 46: 46-55. doi:10.1016/j.sleep.2017.12.020. [8] Berry RB, Budhiraja R, Gottlieb DJ, et al. Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. Deliberations of the sleep apnea definitions task force of the American academy of sleep medicine[J]. J Clin Sleep Med, 2012, 8(5): 597-619. doi:10.5664/jcsm.2172. [9] 施叶雯, 刘海琴, 罗花南, 等. 儿童阻塞性睡眠呼吸暂停综合征的诊断:研究现状与展望[J]. 中国医学文摘(耳鼻咽喉科学), 2018, 33(3): 267-271. doi: 10.19617/j.issn1001-1307. 2018. 03. 267. SHI Yewen, LIU Haiqin, LUO Huanan, et al. The diagnosis of obstructive sleep apnea hypopnea syndrome in children: research status and future[J]. Chinese Medical Digest: Otorhinolaryngology, 2018, 33(3): 267-271. doi: 10.19617/j.issn1001-1307. 2018. 03. 267. [10] Snyder HR, Miyake A, Hankin BL. Advancing understanding of executive function impairments and psychopathology: bridging the gap between clinical and cognitive approaches[J]. Front Psychol, 2015, 6: 328. doi:10.3389/fpsyg.2015.00328. [11] Olivier TW, Mahone EM, Jacobson LA: Wechsler intelligence scale for children. In Encyclopedia of Clinical Neuropsychology[J]. Springer International Publishing, 2017: 1-8.doi: 10.1007/978-3-319-56782-2_1605-2. [12] Canivez GL, McGill RJ. Factor structure of the Differential Ability Scales-Second Edition: Exploratory and hierarchical factor analyses with the core subtests[J]. Psychol Assess, 2016, 28(11): 1475-1488. doi:10.1037/pas0000279. [13] Hunter SJ, Gozal D, Smith DL, et al. Effect of sleep-disordered breathing severity on cognitive performance measures in a large community cohort of young school-aged children[J]. Am J Respir Crit Care Med, 2016, 194(6): 739-747. doi:10.1164/rccm.201510-2099OC. [14] Zhao J, Han SJ, Zhang JS, et al. Association between mild or moderate obstructive sleep apnea-hypopnea syndrome and cognitive dysfunction in children[J]. Sleep Med, 2018, 50: 132-136. doi:10.1016/j.sleep.2018.04.009. [15] Jackman AR, Biggs SN, Walter LM, et al. Sleep-disordered breathing in preschool children is associated with behavioral, but not cognitive, impairments[J]. Sleep Med, 2012, 13(6): 621-631. doi: 10.1016/j.sleep.2012.01.013. [16] Marcus CL, Moore RH, Rosen CL, et al. A randomized trial of adenotonsillectomy for childhood sleep apnea[J]. N Engl J Med, 2013, 368(25): 2366-2376. doi:10.1056/NEJMoa1215881. [17] Bailey CE. Cognitive accuracy and intelligent executive function in the brain and in business[J]. Ann N Y Acad Sci, 2007, 1118: 122-141. doi:10.1196/annals.1412.011. [18] McClelland MM, Cameron CE. Self-regulation and academic achievement in elementary school children[J]. New Dir Child Adolesc Dev, 2011, 2011(133): 29-44. doi:10.1002/cd.302. [19] Dumont R, Willis JO. A developmental neuropsychological assessment[J]. NEPSY, 2008. doi: 10.1007/978-0-387-79061-9_5508. [20] Foss-Feig JH, de la Fontaine N, Tsatsanis K. BRIEF(behavior rating inventory of executive functions)[M] //Encyclopedia of Autism Spectrum Disorders. New York, NY: Springer New York, 2016: 1-5. doi:10.1007/978-1-4614-6435-8_102048-1. [21] Weichard AJ, Walter LM, Hollis SL, et al. Association between slow-wave activity, cognition and behaviour in children with sleep-disordered breathing[J]. Sleep Med, 2016, 25: 49-55. doi:10.1016/j.sleep.2016.06.004. [22] Glisky EL. In encyclopedia of clinical neuropsychology[J]. Springer International Publishing, 2017: 1-6. doi: 10.1007/978-3-319-56782-2_1134-2. [23] Ryan, King. Encyclopedia of Clinical Neuropsychology[D]. Springer New York, 2013. doi:10.1007/978-0-387-79948. [24] Giordani B, Hodges EK, Guire KE, et al. Neuropsychological and behavioral functioning in children with and without obstructive sleep apnea referred for tonsillectomy[J]. J Int Neuropsychol Soc, 2008, 14(4): 571-581. doi:10.1017/S1355617708080776. [25] Centers for Disease Control and Prevention(CDC). Increasing prevalence of parent-reported attention-deficit/hyperactivity disorder among children: -United States, 2003 and 2007[J]. MMWR Morb Mortal Wkly Rep, 2010, 59(44): 1439-1443. [26] Folsom R, Levin P. Conners' continuous performance Test. in encyclopedia of autism spectrum disorders[J]. Springer New York, 2013: 783-787.doi:10.1007/978-1-4419-1698-3. [27] Barnes ME, Gozal D, Molfese DL. Attention in children with obstructive sleep apnoea: an event-related potentials study[J]. Sleep Med, 2012, 13(4): 368-377. doi:10.1016/j.sleep.2011.06.007. [28] 曹丽, 冉域辰, 孟仙. 儿童早期语言发育中的特点分析[J]. 中国儿童保健杂志, 2018, 26(4): 437-439. doi: 10.11852/zgetbjzz2018-26-04-25. CAO Li, RAN Yuchen, MENG Xian. Characteristics of language development in early childhood[J]. Chinese Journal of Child Health Care, 2018, 26(4): 437-439. doi: 10.11852/zgetbjzz2018-26-04-25. [29] 黄敏辉, 陈文娟, 章依文. 语言发育迟缓儿童的年龄与发育特征的相关性研究[J]. 中国儿童保健杂志, 2014, 22(6): 594-596. doi: 10.11852/zgetbjzz2014-22-06-11. HUANG Minhui, CHEN Wenjuan, ZHANG Yiwen. Research of the relationship between the age and developmental characteristic in developmental language delay children[J]. Chinese Journal of Child Health Care, 2014, 22(6): 594-596. doi: 10.11852/zgetbjzz2014-22-06-11. [30] Honaker SM, Gozal D, Bennett J, et al. Sleep-disordered breathing and verbal skills in school-aged community children[J]. Dev Neuropsychol, 2009, 34(5): 588-600. doi:10.1080/87565640903133582. [31] Eigsti, Inge-Marie. Peabody Picture Vocabulary Test.(2017). doi:10.1007/978-1-4614-6435-8_531-3. [32] Moyle M, Long S. Expressive vocabulary test II. In encyclopedia of autism spectrum disorders[J]. Springer New York, 2017: 1-5. doi:10.1007/978-1-4614-6435-8_1665-3. [33] Konstantinopoulou S, Tapia IE. Neurocognitive and behavioural outcomes following intervention for obstructive sleep apnoea syndrome in children. Paediatr Respir Rev. 2016,20:51-54. doi:10.1016/j.prrv.2016.05.004. [34] Krysta K, Bratek A, Zawada K, et al. Cognitive deficits in adults with obstructive sleep apnea compared to children and adolescents[J]. J Neural Transm(Vienna), 2017, 124(Suppl 1):187-201. doi:10.1007/s00702-015-1501-6. [35] Philby MF, Macey PM, Ma RA, et al. reduced regional grey matter volumes in pediatric obstructive sleep apnea[J]. Reports, 2017, 7:44566. doi:10.1038/srep44566 [36] Trosman I. Childhood obstructive sleep apnea syndrome: a review of the 2012 american academy of pediatrics guidelines[J]. Pediatr Ann, 2013, 42(10): 195-199. doi:10.3928/00904481-20130924-09. [37] Zaffanello M, Lo Tartaro P, Piacentini G, et al. Sleep disordered breathing in a cohort of children with achondroplasia: correlation between clinical and instrumental findings[J]. Minerva Pediatr, 2017, 69(6): 481-488. doi:10.23736/S0026-4946.16.04282-1. [38] Huang YS, Guilleminault C, Hwang FM, et al. Inflammatory cytokines in pediatric obstructive sleep apnea[J]. Medicine(Baltimore), 2016, 95(41): e4944. doi:10.1097/MD.0000000000004944. [39] de Lima FF, Mazzotti DR, Tufik S,et al. The role inflammatory response genes in obstructive sleep apnea syndrome: a review[J]. Sleep Breath, 2016,20(1):331-338. doi:10.1007/s11325-015-1226-7. [40] Deguil J, Ravasi L, Lanteaume L,et al. Translational challenge models in support of efficacy studies: effect of cerebral hypoxia on cognitive performances in rodents[J]. CNS Neurol Disord Drug Targets, 2016,15(7):765-776. doi:10.2174/1871527315666160518124926. [41] 刘大波. 重视儿童阻塞性睡眠呼吸暂停低通气综合征睡眠结构紊乱[J]. 山东大学耳鼻喉眼学报, 2018, 32(2): 6-8. doi: 10.6040/j.issn.1673-3770.0.2017.534. LIU Dabo. Evaluation of sleep structure disorder in children with obstructive sleep apnea hypopnea syndrome[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2018, 32(2): 6-8. doi: 10.6040/j.issn.1673-3770.0.2017.534. |
[1] | 张丰珍, 王桂香, 魏沄沄, 张亚梅, 赵靖, 王华, 李宏彬, 李晓丹, 张杰. 合并轻度出血性疾病的扁桃体和(或)腺样体切除术患儿围手术期管理[J]. 山东大学耳鼻喉眼学报, 2022, 36(4): 66-72. |
[2] | 林一杭,李幼瑾. 肠道微生态在儿童变应性鼻炎中的研究现状[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 116-122. |
[3] | 李琳,高正文,崔楠,孙健平,黄贤明,崔静. 儿童慢性鼻窦炎基因表达谱的生物信息学分析[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 171-180. |
[4] | 鹿伟理,姜涛,李宪华. 多重致敏儿童变应性鼻炎患者sIgE特征分析[J]. 山东大学耳鼻喉眼学报, 2022, 36(3): 260-265. |
[5] | 杨扬, 王晓旭, 张杰. 儿童中耳胆脂瘤诊治进展[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 1-6. |
[6] | 高信忠, 林宗通, 沈翎, 刘平凡, 林兴, 许杨杨. 咽鼓管球囊扩张联合腺样体切除术治疗儿童分泌性中耳炎疗效分析[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 7-12. |
[7] | 马宁, 陈敏, 刘薇, 杨扬, 邵剑波, 郝津生, 刘冰, 张晓, 段晓岷, 张祺丰, 张杰. 儿童颞骨骨折临床特点和治疗策略[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 13-19. |
[8] | 胡春燕, 党攀红, 张睿, 樊孟耘. 儿童单侧感音性听力损失的听力学及影像学特征149例分析[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 31-36. |
[9] | 党攀红, 张睿, 胡春燕, 王洁, 樊孟耘. 儿童乳突-颞下迷路外面神经减压术8例临床分析[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 37-42. |
[10] | 刘珊珊, 韩书婧, 王晓旭, 李艳红, 倪鑫, 张杰. 儿童细菌性脑膜炎后听力损害危险因素的系统评价与Meta分析[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 48-54. |
[11] | 焦雪梅,杨扬,李春凤,张晓琳. 鼓膜置管对分泌性中耳炎患儿咽鼓管功能的影响[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 60-63. |
[12] | 王蓬鹏,葛文彤,唐力行,杨小健,张薇,肖潇,韩阳. 开放性鼻整形切口治疗儿童先天性鼻中线囊肿及瘘管4例及文献复习[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 64-69. |
[13] | 李孟辉,郅莉莉,戚凯文,王珊珊,高倩,步美玲,姜荷云,冯绛楠,王金荣. 皮下免疫治疗对单一尘螨和合并霉菌过敏儿童哮喘的临床研究[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 75-80. |
[14] | 赵海涛, 王亚芳, 赫莉, 陈文静, 邢民者, 郑文娟,阎玉彦,刘晓峰. 可视喉镜在先天性舌根囊肿患儿手术麻醉中的应用[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 106-110. |
[15] | 师晓丽, 牟鸿. 多学科联合诊治重度儿童阻塞性睡眠呼吸暂停综合征并发肺动脉高压1例[J]. 山东大学耳鼻喉眼学报, 2022, 36(1): 116-119. |
|