miRNA在头颈肿瘤的应用进展

doi:10.6040/j.issn.1673-3770.0.2015.170

山东大学耳鼻喉眼学报 ›› 2015, Vol. 29 ›› Issue (5): 79-82.doi: 10.6040/j.issn.1673-3770.0.2015.170

miRNA在头颈肿瘤的应用进展

周娟, 郑家法

南华大学附属南华医院耳鼻咽喉科, 湖南衡阳 421001

收稿日期:2015-04-24 修回日期:2015-09-22 出版日期:2015-10-16 发布日期:2015-10-16
通讯作者: 郑家法,E-mail:13975466338@139.com E-mail:13975466338@139.com
作者简介:周娟,E-mail:1075765033@qq.com

Research progress of miRNA in head and neck cancers

ZHOU Juan, ZHENG Jiafa

Department of Otorhinolaryngology Head and Neck Surgery, Nanhua Hospital Affiliated to University of South China, Hengyang 421001, Hunan, China

Received:2015-04-24 Revised:2015-09-22 Online:2015-10-16 Published:2015-10-16

摘要/Abstract

摘要： microRNA又称miRNA,是一类非编码的单链小分子RNA,通过与靶mRNA的3'UTR(3'末端非翻译区)不完全或完全互补配对调节基因的表达,在肿瘤的发生、发展中扮演着重要角色。本文就miRNA在头颈肿瘤的诊断、预后、治疗等方面作一综述。

关键词: miRNA, 头颈肿瘤, 基因

Abstract: A microRNA, abbreviated miRNA, is a non-coding single-stranded small molecular RNA. Through incomplete or complete complementary pairing with target mRNA 3' UTR (3' end untranslated region), it plays an important role in the occurrence and development of tumors. This paper reviews the role of miRNA in the diagnosis, prognosis and treatment of head and neck cancers.

Key words: Head and neck cancers, miRNA, Gene

中图分类号:

R739.91

周娟, 郑家法. miRNA在头颈肿瘤的应用进展[J]. 山东大学耳鼻喉眼学报, 2015, 29(5): 79-82.

ZHOU Juan, ZHENG Jiafa. Research progress of miRNA in head and neck cancers[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(5): 79-82.

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miRNA在头颈肿瘤的应用进展

Research progress of miRNA in head and neck cancers

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