JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY) ›› 2016, Vol. 30 ›› Issue (2): 84-86.doi: 10.6040/j.issn.1673-3770.0.2015.366

Previous Articles     Next Articles

Analysis on efficacy of treatment of corneal epithelial dysfunction after cataract surgery.

LIN Li, YANG Xu   

  1. Department of Ophthalmology, Suining Central Hosptial, Suining 629000, Sichuan, China
  • Received:2015-08-26 Online:2016-04-16 Published:2016-04-16

PDF (PC)

666

Abstract: Objective To observe the clinical efficacy of autologous serum combined with artificial tears without preservative in the treatment of corneal epithelial dysfunction after cataract surgery. Methods Twenty-nine patients with corneal epithelial dysfunction after phacoemulsification combined with intraocular lens implantation under topical anesthesia were selected as research objects, and treated with autologous serum combined with artificial tears without preservative. The clinical manifestations of patients were observed. Slit-lamp examination and fluorescein vital staining were used to observe the conditions of conjunctival congestion, corneal epithelial repair, recession of epithelial edema and fluorescein staining, and visual function repair was compared before and after treatment. Results About 1 to 2 weeks after treatment, eye irritation symptoms of 29 patients, including ophthalmodynia, foreign body sensation in the eye and photophoby, gradually alleviated and disappeared. Slit-lamp examination revealed that conjunctival congestion improved gradually; Corneal epithelium healed, and the mean healing time was(12.60±3.91)d. Vision improved in varying degree in all cases. Conclusion Autologous serum combined with artificial tears without preservative can promote corneal epithelial healing of patients with corneal epithelial dysfunction after cataract surgery and improve the visual function.

Key words: Cataract, Corneal epithelial dysfunction, Autologous serum

CLC Number: 

  • R772.2
[1] 王丽天. 高度重视白内障手术的并发症[J]. 中华眼科杂志, 2000, 5(5):327-329. WANG Litian. Paying high attention to cataract surgery complications[J]. Chin J Ophthalmol, 2000, 5(5):327-329.
[2] 陶春潇, 赵敏. 自体血清在眼表疾病治疗中应用及进展[J]. 中国实用眼科杂志, 2009, 5(5):425-428. TAO Chunxiao, ZHAO Min. Application and advances of autologous serum in ocular surface diseases[J]. Chin J Prac Ophthalmol, 2009, 5(5):425-428.
[3] 邱晓頔, 龚岚, 陈敏洁. 维生素A棕榈酸酯对兔机械性角膜上皮损伤愈合及结膜杯状细胞的作用研究[J]. 中华眼科杂志, 2010, 46(2):151-160. QIU Xiaodi, GONG Lan, CHEN Minjie. Research on effects of vitamin a palmitate on repair of mechanical corneal epithelial defects and conjunctival goblet cells in rabbits[J]. Chin J Ophthalmol, 2010, 46(2):151-160.
[4] 孙旭光, 王森. 重视白内障术后角膜上皮细胞功能障碍[J]. 中华眼科杂志, 2015, 51(3):161-162. SUN Xuguang, WANG Sen. Paying attention to corneal epithelial cell dysfunction after cataract surgery[J]. Chin J Ophthalmol, 2015, 51(3):161-162.
[5] 郑天玉, 张忆, 徐建江, 等. 不同年龄人角膜缘基底细胞增殖力和超微结构观察[J]. 中华眼科杂志, 2009, 45(9):799-804. ZHENG Tianyu, ZHANG Yi, XU Jianjiang, et al. Proliferative ability and ultramicrostructure of basal limbal epithelial cells in different age group of normal subjects[J]. Chin J Ophthalmol, 2009, 45(9):799-804.
[6] 杜园园, 王跃, 吴宏. 抗生素滴眼剂致药物毒性眼表损害分析[J]. 中国实验诊断学, 2008, 12(9):1166-1167. DU Yuanyuan, WANG Yue, WU Hong. Analysis on ocular surface damage of drug toxicity induced by antibiotic eye drops[J]. Chin J Lab Diag, 2008, 12(9):1166-1167.
[7] 景桂莲, 李月礼, 岳军, 等. 白内障术后局部滴眼诱发药源性角膜病变的临床研究[J]. 国际眼科杂志, 2010, 10(8):1537-1538. JING Guilian, LI Yueli, YUE Jun, et al. Local eye drops after cataract surgery induced drug-induced corneal lesion[J]. Inter J Ophthalmol, 2010, 10(8):1537-1538.
[8] 欧阳平波, 段宣初. 局部用抗青光眼药物对眼表的损伤及预防[J]. 中华眼科杂志, 2012, 48(6):557-561. OUYANG Pingbo, DUAN Xuanchu. Ocular surface injury resulted from topical anti-glaucoma medications: prevention and cure[J]. Chin J Ophthalmol, 2012, 48(6):557-561.
[9] 朱姝, 贾卉. 糖尿病角膜上皮和泪膜改变的研究进展[J]. 眼科新进展, 2007, 4(4):318-320. ZHU Shu, JIA Hui. Research advances of diabetic corneal epithelium and tear film change[J]. Rec Adv Ophthalmol, 2007, 4(4):318-320.
[10] 邓世靖, 王智群, 张阳, 等. 睑缘炎相关角膜病变特点及其睑板腺功能的临床观察[J]. 眼科, 2013, 22(3):149-153. DENG Shijing, WANG Zhiqun, ZHANG Yang, et al. Clinical observation on characteristics of blepharitis-related keratopathy and its meibomian gland function[J]. Ophthalmol Chin, 2013, 22(3):149-153.
[11] Dalmon C A, Chandra N S, Jeng B H. Use of autologous serum eyedrops for the treatment of ocular surface disease: first US experience in a large population as an insurance-covered benefit[J]. Arch Ophthalmol, 2012, 130(12):1612-1613.
[12] Noble B A, Maclennan S A, Burr J, et al. Comparison of autologous serum eye drops with conventional therapy in a randomised controlled crossover trial for ocular surface disease[J]. Br J Ophthalmol, 2004, 88(5):647-652.
[13] 江臻颖, 瞿小妹. 硅水凝胶镜片作为绷带型角膜接触镜的应用前景[J]. 中华眼视光学与视觉科学杂志, 2012, 2(2):122-125. JIANG Zhenying, QU Xiaomei. Application potential of silicone hydrogel contact lenses used as a bandage[J]. Chin J Optom Ophthalmol Vis Sci, 2012, 14(2):122-125.
[1] ZHENG Wanqiu, WAN Wenjuan, LI Can. Application of anterior chamber maintainer in posterior capsular rupture in cataract surgery. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 9-12.
[2] WEI Chao, ZHANG Han. Multifocal intraocular lens: progress in clinical application. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 29-35.
[3] BI Hongsheng. Design of treatment protocol in refractive cataract surgery is important for postoperative visual outcomes. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 1-4.
[4] YANG Yuhuan, ZHANG Jie, ZHANG Jinpeng, YAN Hong. Effects of mydriasis on anterior chamber parameters measured by a Pentacam before and after cataract surgery. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 5-8.
[5] TIAN Jing, LIAO Xuan, LAN Changjun, TAN Qingqing, LIN Jia, WEN Baiwei. Comparison of high order aberrations in pseudophakia with spherical intraocular lens and aspheric intraocular lens implantation. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 13-17.
[6] JI Shuaifei, ZHANG Jie, YAN Hong. Selection of intraocular lens for patients with age-related macular degeneration. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2017, 31(4): 36-39.
[7] LIU Lu, LIANG Hao. Distribution of corneal astigmatism among middle aged and senior citizens with cataract. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(6): 75-77.
[8] DENG Zhifeng. The clinical study on the improved phacoemulsification. [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2016, 30(3): 85-88.
[9] LIU Zhao, WU Changrui, GAO Ning. Evaluation of meibomian gland dysfunction after phacoemulsification surgery [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(6): 68-70.
[10] LIU Zhi-gao, YAN Shi-long, HU Zun-xia, SUN Tong-xin, YANG Ming, WANG Yu. Prevalence investigation on rural cataract patients with diabetes and diabetes retinal fundus lesions in Jinan city of Shandong province [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(1): 38-39.
[11] ZHU Zi-cheng, WEN Yue-chun, WU Zhang-you, KE Gen-jie. Effects of different intraocular lens on macula area of high myopia associated with cataract [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2015, 29(1): 40-43.
[12] SUN Hong-yi, ZHANG Han. Changes of macular thickness under optical coherent tomography in type 2 diabetic patients with cataract after phacoemulsification surgery and IOL implantation [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(6): 72-76.
[13] YAN Shi-long, YANG Ming, HU Zun-xia, LIU Zhi-gao, LI Jing-hai. Clinical analysis of 7 patients with phacolytic glaucoma treated by phacoemulsification [J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(5): 79-81.
[14] ZHANG Ai-hui1， ZHU Ling1, ZHANG Jin-zhi1， ZHANG Wei2. Correlation between cataract phacoemulsification with intraocular lens implantation and age-related macular degeneration [J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(5): 77-83.
[15] SHI Shao-dan1, LIU Jing2, ZHANG Wei2, ZHANG Han2. Systematic review of surgical treatment for primary angle-closure glaucoma accompanied with Cataract [J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(5): 84-90.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] ZHAO Li-min, NI Kun, WU Jia-li, CHEN Shu-mei, LI Xiao-yan. Etiology and treatment of inspiratory laryngeal stridor in infants[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(2): 49 -51 .
[2] SHI Chun-sheng1, ZHANG Qing-quan2， WANG Qiang2, SUN Yan2, GE Chang-yi1. Application of flaps in the reconstruction of soft palate defects[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(2): 86 -88 .
[3] ZHANG Ling1, SUN Chuan-yi1, XU An-ting2. 1 case of petrous apex cholesteatoma deafness patients[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(2): 93 -94 .
[4] . [J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(4): 1 -3 .
[5] LUO Hui-xiu, FAN Chun-tao, DENG Yan-hua. Therapeutic effects of adenoidectomy and tonsillectomy in children with obstructive sleep apnea hypopnea syndrome[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(4): 17 -20 .
[6] HAO Ying-juan1, YANG Qing-song2, ZHOU Yue-hua2, YI Sheng-ping1， ZHAI Chang-bin2. Characteristics of thin corneal flaps created with Wavelight FS200 femtosecond laser[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(4): 26 -31 .
[7] WEN Hua-ming1, LI Hai-xiang2. Application of trianglar function method to calculate intra ocular lens power after myopic laser in situ keratomileusis[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(5): 74 -76 .
[8] ZHU Jian， HE Qing-qing， ZHENG Lu-ming， FAN Zi-yi， ZHAO Guo-wei， HOU Lei， SHI Hou-bin. Clinical analysis for 57 re-operational cases of differentiated thyroid cancer[J]. J Otolaryngol Ophthalmol Shandong Univ, 2013, 27(6): 9 -12 .
[9] LI Shao-hua, SUN Yi-fan, LU Biao-qing. Application of double vascularized soft tissue flap in open radical mastoidectomy[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(1): 6 -7 .
[10] WEI Xi-jian1, YIN Rui-lan2, GUO Xing3. Expression of a proliferation-inducing ligand in laryngeal squamous cell carcinoma[J]. JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY), 2014, 28(1): 14 -16 .
Website Copyright: Editorial Office of Journal of Otolaryngology and Ophthalmology of Shandong University
Address: No.27 Shanda South Road, Jinan, Shandong, China. Post code: 250100 Tel: +86-0531-88366912 Email: ebhxb@sdu.edu.cn Supported by Beijing Magtech Co.Ltd