Objective〓〖WTBZ〗To explore the relationships among different refractive components following penetrating keratoplasty(PKP) and to evaluate the refractive changes induced by PKP. 〖WTHZ〗Methods〓〖WTBZ〗32 New Zealand white rabbits were divided into groups A, B, C and D. The diameter of the adopt hole was 7.0mm in each group, but the donor diameter was 7.0mm, 7.25mm, 7.5mm and 8.0mm in groups A, B, C and D. The differences of donor button and host bed(Δd), corneal dioptric power, corneal thickness, anterior chamber depth and lense thickness were supposedas cause quantity X1, X2, X3, X4 and X5, and the axial length served as the result quantity. All the refractive components were examined before the operations and 1 week, 2 weeks, 1 month, 2 months and 3 months after the operations. Mathematic models of regression equations were built. 〖WTHZ〗Results〓〖WTBZ〗Before the operations, no statistical differences of the refractive components were found in the four groups. After the operations, the mathematic models of regression equations were built as follows: 3 month after the operations: Y=15.238+0.199X1+
0.544X2-0.060X3+0.129X4-0.094X5. 〖WTHZ〗Conclusion〓〖WTBZ〗Different sizes of donor button and host bed (Δd) can induce changes of refractive components during PKP. The established mathematic model of regression equations is helpful in quantifying the refractive error and controlling the refraction of PKP.
