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Table of Content

    16 August 2008 Volume 22 Issue 4
      
    Articles
    Relationship between adult snoring and oropharyngeal stenosis scoring

    CAI Qian,SU Zhen-zhong,WEN Wei-ping,CHAI Li-ping,YE Hui,TENG Yi-shu,WU Xuan

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  289-292 . 
    Abstract ( 2473 )   PDF (283KB) ( 1635 )   Save
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    Objective〓〖WTBZ〗To explore the snoring status of adult people in the Guangzhou area and to explore the relationship between the shape of the oropharynx and snoring. 〖WTHZ〗Methods〓〖WTBZ〗354 persons aged from 20 to 87 years were investigated. 329 persons without other obstructions and tonsil operations and 42 people with obstructive sleep apnea-hypopnea syndrome (OSAHS) were observed. The oropharynx was classified into type I, II, III and IV based on the structure-induced stenosis: the tonsil, uvula, lateral pharyngeal band, soft palate and root of the tongue. 〖WTHZ〗Results〓〖WTBZ〗39.8% of persons were habitual snorers; male and female snorers had similar pharyngeal types and
    had approximately the same proportion. With an increase of age, patients younger
    than 60 years showed an increase of snoring, the worse the oropharyngeal stenosis (type Ⅲ, Ⅳ) was, the more the possibility of snoring. No close relationship was found between OSAHS status and pharyngeal stenosis. 〖WTHZ〗Conclusion〓〖WTBZ〗Oropharyngeal stenosis is one of the factors for OSAHS. Oropharyngeal typing can benefit the screening of habitual snorers and OSAHS-oriented people but can not define OSAHS, and it should be combined with polysomnography (PSG) to examine OSAHS.

    Hypophyseoma with hypertrophic corpus linguae induced severe obstructive
    sleep apnea hypopnea syndrome in 3 cases

    ZHANG Qing-quan,SONG Xi-cheng,WANG Yan
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  293-295 . 
    Abstract ( 1851 )   PDF (258KB) ( 1217 )   Save
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    Objective〓〖WTBZ〗To explore the surgical effects of severe obstructive sleep apnea hypopnea syndrome (OSAHS) induced by hypophyseoma with hypertrophic corpus linguae. 〖WTHZ〗Method〓〖WTBZ〗3 cases were treated with uvulopalatopharyngolasty (UPPP) in combination with partial radix linguae and corpus linguae median line resection via the extro-neck approach. 〖WTHZ〗Results〓〖WTBZ〗2 cases were healed and 1 case suffered from infection in the neck inter-space which was healed after draining, dressing change and antibiotics administration on day 11. Followed up from six months to three years, 3 cases felt well, had no somnolence in daytime, and the somnus monitoring on the 6th and 12th showed that the response rate was 100%. 〖WTHZ〗Conclusions〓〖WTBZ〗Uvulopalatopharyngolasty (UPPP) in combination with radix linguae, corpus linguae and lingual bone operation via the extro-cervical approach is effective for solving obstructions in the palatopharygeum and glossopharyngeum planes for severe obstructive sleep apnea hypopnea syndrome (OSAHS) induced by hypophyseoma with hypertrophic corpus linguae.

    Plasma radio-frequency ablation combined with modified uvulopalatopharyngoplasty in treatment of 50 cases of obstructive sleep apnea hypopnea syndrome

    WAN Jing-ming
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  296-298 . 
    Abstract ( 1562 )   PDF (264KB) ( 1116 )   Save
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    Objective〓〖WTBZ〗To investigate the clinical effect of plasma radio-frequency ablation combined with modified uvulopalatopharyngoplasty(UPPP) in treatment of obstructive sleep apnea hypopnea syndrome(OSAHS). 〖WTHZ〗Method〓〖WTBZ〗The clinical data of 50 cases were retrospectively analyzed. 〖WTHZ〗Results〓〖WTBZ〗At post-operative 6 months, 60% cases were significantly improved, 35% were improved, 5% were not improved, and the total response rate was 95%. At post-operative 12 months, 58% cases were significantly improved, 31% were improved, 11% were not improved, and the total response rate was 89%. The longest times of apnea and hypopnea, the apnea hypopnea index(AHI) and the lowest arterial oxygeon saturation(LSaO2) were statistically different between those before and after the operations, but were not significantly different between those of post-operative 6 months and 12 months. 〖WTHZ〗Conclusion〓〖WTBZ〗Plasma radio-frequency ablation combined with modified UPPPis effective for OSAHS.

    Immunohistochemistry and serial section in detection of lymph node micrometastasis of head and neck squamous cell carcinoma

    ZHANG Jian-li,WANG Yue-jian,CHEN Wei-xiong,HU Wei-wei,LI Guang-min

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  299-303 . 
    Abstract ( 1874 )   PDF (357KB) ( 1376 )   Save
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    Objective〓〖WTBZ〗To detect lymph node micro-metastasis and explore the clinical significance of lymph node micrometastasis in head and neck squamous cell carcinoma. 〖WTHZ〗Methods〓〖WTBZ〗25 lymph nodes taken from head and neck squamous cell carcinoma and frozen in the operations, and 223 lymph nodes taken form 14 cases of hypopharynx cancer or supraglottis cancer and serial sectioned were stained with the EnvisionTM system with monoclonal antibody CK(AE1/AE3) and H&E staining. The results were compared. 〖WTHZ〗Results〓〖WTBZ〗Two micro-metastasis lymph nodes which were not found by routine frozen section histological staining were found by the quick EnvisionTM system, and five micro-metastasis lymph nodes were detected from 216 H&E negative lymph nodes by using the immunohistochemisty EnvisionTM system. 〖WTHZ〗Conclusion〓〖WTBZ〗The EnvisionTM system is effective and reliable and can be used for intra-operative micro-metastasis examination. Patients with two or more micro-metastasis lymph nodes may have a poor prognosis.

    Polymorphism of mitochondrial DNA at the D-310 region in laryngeal squamous cancer cells

    HAN Yue-chen,FAN Zhao-min,XU Wei,LI Jian-feng,L〖AKU¨] Zheng-hua,WANG Hai-bo

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  304-306 . 
    Abstract ( 1518 )   PDF (513KB) ( 1030 )   Save
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    Objective〓〖WTBZ〗To investigate the polymorphism of the D310 region of somatic mitochondrial DNA (mtDNA) in the human primary laryngeal squamous cell cancer. 〖WTHZ〗Methods〓〖WTBZ〗Eleven cases of laryngeal squamous cell cancer were collected from in-patients who were confirmed by pathologic studies. The total DNA was amplified to identify the polymorphism of the D-310 region by the PCR technique, polyacrylamide gel electrophoresis and sequencing. 〖WTHZ〗Results〓〖WTBZ〗Changes in length of short C base-repetitive sequencing were found in the conserved D310 region in 8 cases (72.73%). Most of the mutations (8/11) were homoplasmic mutations, and the others (3/11) were hytroplasmic mutations. Of the 6 kinds of mutation changes, insertion of one cytosine at the D-310 region was the most common, ranked about 50%. 〖WTHZ〗Conclusions〓〖WTBZ〗The D310 region located in the D-Loop region could be a mutational hotspot in laryngeal squamous cell cancer.

    CO2 laser in treatment of T1 well-differentiated squamouscell carcinoma in the glottic portion involving the anterior commissure under microscopy
    MING Wei,QU Ji-ning,HUA Qing-quan,ZHAN Han-zhang
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  307-309 . 
    Abstract ( 1483 )   PDF (227KB) ( 1253 )   Save
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    Objective〓〖WTBZ〗To evaluate the oncologic safety of microscopic CO2 laser in treatment of stage T1 well-differentiated squamous cell carcinoma in the glottic portion involving the anterior commissure. 〖WTHZ〗Method〓〖WTBZ〗The clinical data of 56 cases from March 2005 to June 2007 were retrospectively analyzed. 〖WTHZ〗Results〓〖WTBZ〗11 cases (19.6%) locally recurred, of them, 4 cases (4/37) were unilateral cord lesion, 5 (5/13) were cord and anterior commissure lesion, and 2 (2/6) were horseshoes lesion involving both the cords and the anterior commissure. The recurrent rate of cases of cord and anterior commissure lesion and horseshoes lesion was higher than that of unilateral cord lesion. Followed up for an average of 26.4 months (10-32 months), the preservation rate of the laryngeal function was 96.4%. 〖WTHZ〗Conclusion〓〖WTBZ〗Microscopic CO2 laser for glottic carcinoma is limited to some extent, and it should be carefully used in carcinoma involving the anterior commissure.

    Effect of microwave radiation on cell proliferation activity and the cell cycle of nasopharyngeal carcinoma

    MA Jing,LIU Bin
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  310-312 . 
    Abstract ( 1525 )   PDF (632KB) ( 1493 )   Save
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    Objective〓〖WTBZ〗To explore the effect of microwave radiation on cell proliferation activity and the cell cycle of nasopharyngeal carcinoma. 〖WTHZ〗Methods〓〖WTBZ〗There were four groups: the control, 10, 20 and 30mW/cm2 microwave radiation groups. MTT and flow cytometry (FCM) methods were used to detect the cell proliferation activity and the cell cycle of nasopharyngeal carcinoma. 〖WTHZ〗Result〓〖WTBZ〗With an increase of microwave radiation dosage, the MTT assay showed that the rate of cell activity was reduced from 100% to 76.75% and 65.07% at 20 and 30 mW/cm2 microwave radiation and sub-diploidy peaks were found. 〖WTHZ〗Conclusion〓〖WTBZ〗Microwave radiation inhibits cell proliferation and promotes cell apoptosis of nasopharyngeal carcinoma.

    Velopharyngeal insufficiency following radiotherapy in patients with nasopharyngeal carcinoma

    HE Xiao-song,LEI Xun,LING Yue-fu,DENG Ming
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  313-315 . 
    Abstract ( 2024 )   PDF (258KB) ( 1479 )   Save
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    Objective〓〖WTBZ〗To explore the possible reasons, diagnosis and treatment of velopharyngeal insufficiency in patients with nasopharyngeal carcinoma (NPC) after radiotherapy. 〖WTHZ〗Method〓〖WTBZ〗16 cases of velopharyngeal insufficiency including 14 cases of soft palate dysfunction and 2 cases of soft palate dysfunction with hard palate perforation were retrospectively analyzed. [WTHZ]Results〓〖WTBZ〗The radiotherapy dose of this group was from 68 to 75 Gy and an average of 70Gy. Velopharyngeal insufficiency occurred within 5 years after radiotherapy and an average of 8.3 years, and it mainly had open rhinolalia and transnasal-reflux. Position-pressure eating, palate back-plate use and nasal cavity irrigation relievedthe symptoms. 〖WTHZ〗Conclusion〓〖WTBZ〗Velopharyngeal insufficiency slowly develops in patients with NPC after radiotherapy. With a routine dose, radiotherapy is not the key factor for velopharyngeal insufficiency, moreover individual differences may be more important. Hard palate perforation may be the result of chronic ischemic, and it may be relieved by suitable treatments.

    Heterogenerty (cattle) acellular dermal matrix repairing mucosa in otolaryngology reconstruction surgeries
    SUN Yan,ZHANG Qing-quan,ZHANG Hua,SONG Xi-cheng,ZHAO Li-min,WANG Yan,JIANG Shao-hong,WANG Qiang
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  316-319 . 
    Abstract ( 1656 )   PDF (299KB) ( 1454 )   Save
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    Objective〓〖WTBZ〗To explore the clinical effect of heterogeneity (cattle) acellular deunal matrix in mucosa defect repair in otolaryngology surgeries.
    〖WTHZ〗Method
    s〓〖WTBZ〗64 cases of mucosa defect were treated with heterogeneity acellular deunal matrix, 53 of them were neoplasms. After the operations, patients were given antibiotics based on secretions or pus, also the acellular dermis should be kept moist and patients with neck esophageal squamous carcinoma or hypopharynx and larynx carcinoma received nasal feeding. 〖WTHZ〗Results〓〖WTBZ〗60 cases were healed. 1 case of hypopharynx and 1 of larynx carcinoma infected by pharynx fistula, and 1 case of larynx carcinoma infected by larynx fistula were healed after dressing change and expectant treatment. No exclusiveness and irritation were found during the treatments. 〖WTHZ〗Conclusion〓〖WTBZ〗Heterogeneity acellular deunal matrix is easily obtained and is effective in repairing mucosa defects.

    Endoscopic medial maxillectomy in treatment of inverted nasal papilloma

    ZHANG Xue-bin,GAO Yong-ping,CAI Jun-ming,LI Ming-jiang,LIN Qun,LI Chun-miao

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  320-321 . 
    Abstract ( 1497 )   PDF (197KB) ( 1303 )   Save
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    Objective〓〖WTBZ〗To investigate the characteristics of endoscopic medial maxillectomy in treatment of inverted nasal papilloma. 〖WTHZ〗Methods〓〖WTBZ〗33 cases of endoscopic medial maxillectomy were retrospectively analyzed. Bleeding amount, operation time, complications and recurrence were compared between the endoscopic treatment group and the traditional treatment group. 〖WTHZ〗Results〓〖WTBZ〗In the endoscopic group, an average 80mL of bleeding, 2-hour operation and no severe complications occurred, and the recurrence rate was 14.2%, however, an average 500?mL of bleeding, 3-hour operation and 3 complications were found, and the recurrence rate was 35.7% in the traditional group. 〖WTHZ〗Conclusion〓〖WTBZ〗Endoscopic medial maxillectomy is an effective procedure for inverted nasal papilloma.

    Thyroglossal duct carcinoma: one case report and a literature review
    CHU Jiu-sheng,HUANG Yong-jiu,BAO Xue-li,TIAN Wei-zhong
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  322-324 . 
    Abstract ( 1428 )   PDF (377KB) ( 1500 )   Save
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    Objective〓〖WTBZ〗To investigate the diagnosis and treatment methods for thyroglossal duct carcinoma. 〖WTHZ〗Methods〓〖WTBZ〗The clinical data of 1 case of thyroglossal duct papillary carcinoma were retrospectively analyzed. Also, with a literature review, the genesis, diagnosis and therapy of thyroglossal duct carcinoma were analyzed. 〖WTHZ〗Results〓〖WTBZ〗Most thyroglossal duct carcinoma were papillary and had multi-cystic structures or mural nodule or calcification on CT. Followed up for almost 1 year, no relapse occurred. 〖WTHZ〗Conclusion〓〖WTBZ〗Thyroglossal duct carcinoma quickly grows. CT on neck and fine-needle aspiration are important clues for pre-operative diagnosis. The sistrunk procedure is effective for tumor removal.

    Selective low position and horizontal tracheotomy in larynx neoplasm
    LI Guang-hao
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  325-326 . 
    Abstract ( 1670 )   PDF (1KB) ( 1383 )   Save
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    Objective〓〖WTBZ〗To explore the effects of selective low position and horizontal tracheotomy on the decrease of complications in larynx neoplasm. 〖WTHZ〗Method〓〖WTBZ〗Low position horizontal tracheotomy was performed on 37 cases of pharyngeal or laryngeal tumors before surgical treatment, and possible complications were observed.〖WTHZ〗Results〓〖WTBZ〗No bleeding, difficulty in removing the canular, unclosed fistula and pneumothorax happened. 〖WTHZ〗Conclusion〓〖WTBZ〗This procedure has advantages of little bleeding, less infection, small scar and rare complications.

    Effect of cochlear implantation on hearing and speech rehabilitation

    LIU Feng-an,CHEN Hong-jie,HU Hong-yi,ZHENG Shi-xin
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  333-335 . 
    Abstract ( 1722 )   PDF (267KB) ( 1206 )   Save
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    Objective〓〖WTBZ〗To investigate factors affecting hearing and speech rehabilitation following cochlear implantation. 〖WTHZ〗Methods〓〖WTBZ〗Twenty-four cases of bilateral severe or profound sensorineural deafness had intelligence, audiology, aural image and hearing-aids estimated before multi-channel cochlear implantation through the facial nerve recess approach. Postoperative electrode resistance was recorded and mapping was carried out one month after the operations. Pre-lingual patients received audition and speech or language skill rehabilitation trainings. 〖WTHZ〗Results〓〖WTBZ〗Twenty-three patients were successfully operated on and one with electrode placement was operated on twice. During the follow-up, two patients had short-term facial paralysis and one had a short period of vertigo. An X-ray film of the temporal bones two weeks later proved that all electrodes were properly located in the cochlear. Mapping performed one month after the surgery showed that hearing was completely recovered in 24 cases. Three post-lingual deaf patients were able to hear and speak. Other per-lingual deaf patients received audition and speech or language skill rehabilitation trainings. During a follow-up of 4-6 years, the language understanding rate was 80% and the appropriate expectation was satisfied. 〖WTHZ〗Conclusion〓〖WTBZ〗Cochlear implantation is a routine treatment for bilateral severe or profound sensorineural deafness. Its therapeutic effectiveness is correlated with many factors including indication, age, hearing-aids before the operations, remnant audition, course of operation, electrode position, audition and speech or language skill rehabilitation trainings and appropriate expectations.

    Chondroseptum or ethmoid in repairing of nasal septum perforation under endoscopy
    ZHANG Ji-zhong,LI Da-jian
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  336-337 . 
    Abstract ( 1437 )   PDF (213KB) ( 1505 )   Save
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    Objective〓〖WTBZ〗To evaluate the clinical effects of nasal endoscopic neoplasty in treatment of nasal septum perforation with chondroseptum or ethmoid. 〖WTHZ〗Methods〓〖WTBZ〗22 cases of nasal septum perforation, of which, 12 cases were induced by nasal septum surgery, 2 cases by trauma, 2 cases by chemical rusty, and 3 cases non-causal, were treated by nasal endoscopic neoplasty with chondroseptum or ethmoid. After the operations, MEBO was used to promote nearby tissues grow towards the perforations. 〖WTHZ〗Results〓〖WTBZ〗All cases were successfully repaired with the squamous epithelization from 25 to 62 days. Followed up from 2 to 3 years, no surgical complications happened. 〖WTHZ〗Conclusion〓〖WTBZ〗Nasal endoscopic neoplasty for nasal septum perforation with chondroseptum or ethmoid is safe, handy and effective.

    Dissociated or rotary flap transplantation in treatment of nasal and facial injuries

    ZHANG Duan-he,CHEN Jian-ping,MA Zheng-wang,WANG Cheng,WANG Hu-guo

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  338-339 . 
    Abstract ( 1603 )   PDF (220KB) ( 934 )   Save
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    Objective〓〖WTBZ〗To repair nasal and facial injuries induced by illness or wound so as to recover their normal function and cosmetology. 〖WTHZ〗 Method〓〖WTBZ〗Self-dissociated or rotary flaps were transplanted to damaged skins, and then were closely sutured and partly pressed. 〖WTHZ〗Result〓〖WTBZ〗All the 36 cases were successfully operated on. 〖WTHZ〗Conclusion〓〖WTBZ〗Self-dissociated or rotary flaps are reliable for repairing nasal and facial injuries.

    Oil gauze of traditional Chinese medicine for nasal packing after functional endoscopic sinus surgery

    YU De-xian,ZHANG Wen-shan,PI Shi-jun,CAO Gui-xia,LI Yong-qiang,MA Qing,HUANG Jian

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  340-342 . 
    Abstract ( 1924 )   PDF (271KB) ( 1580 )   Save
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    Objective〓〖WTBZ〗To develop a new nasal packing material which is suitable for relieving pain and reducing bleeding and is economical. 〖WTHZ〗Methods〓〖WTBZ〗Based upon traditional Chinese medical theory, herb oil gauzes were made and used in 85 cases of functional endoscopic sinus surgery ( FESS ). Also, paraffin gauzes were used in 101 cases. Pains, bleeding, and smell were analyzed in the two groups. 〖WTHZ〗Results〓〖WTBZ〗The incidence rate of nasal pain or headache, post-operative nasal bleeding, nasal bleeding when removing the packing materials and bad smell were 25.74%,30.69%,42.57% and 40.59% in the paraffin gauze group, however they were 17.65%,16.47%,12.94% and 16.47% in the herb oil gauze group. The differences were statistically significant (P<0.01). 〖WTHZ〗Conclusions〓〖WTBZ〗This traditional Chinese medical herb oil gauze has advantages of little pain, little bleeding, quick healing and is economical.

    Kaino-sinus syndrome: with a report of 3 cases and literature review

    ZHANG Qing-quan,SONG Xi-cheng,ZHANG Hua,SUN Yan,WANG Qiang,WANG You-fu

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  343-344 . 
    Abstract ( 1400 )   PDF (223KB) ( 1198 )   Save
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    Objective〓〖WTBZ〗To explore the etiological factors and treatment for kaino-sinus syndrome. 〖WTHZ〗Methods〓〖WTBZ〗The clinical data of 3 cases of kaino-sinus syndrome following maxillary sinus or sphenoidal sinus surgeries were retrospectively analyzed. 〖WTHZ〗Results〓〖WTBZ〗Excessively enlarged sinus apertures, excessive removal of tissues and fore-lying sinus apertures were causes for kaino-sinus syndrome; also, the mental type and function state of the autonomic nerve system were related to kaino-sinus syndrome. 〖WTHZ〗Conclusions〓〖WTBZ〗In nasal cavity and sinuses surgeries, lesions should be completely removed, and also the structure of the tissues, especially of the sinus apertures should be maintained.

    Effect of trans-nasal endoscopic sinus surgery on chronic sinusitis
    WEI Li-ping,LIU Hong-ying,XU Zhao-xia
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  345-346 . 
    Abstract ( 1530 )   PDF (229KB) ( 1076 )   Save
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    bjective〓〖WTBZ〗To explore the curative effects of transnasal endoscopic sinus surgery on chronic sinusitis. 〖WTHZ〗Methods〓〖WTBZ〗380 cases of chronic sinusitis were treated with endoscopic sinus surgery in 2000-2006. Of them, 65 cases were type Ⅰ,236 cases were type Ⅱ and 79 cases were type Ⅲ. 〖WTHZ〗Result〓〖WTBZ〗The curative rate was 92.3%, 84.3% and 67.1% in typeⅠ, Ⅱand Ⅲ. 〖WTHZ〗Conclusion〓〖WTBZ〗The clinical curative rate is related to clinical type, operated area and post-operative treatments.

    Culture of the human Tenon′s capsule fibroblast cells in vitro
    CHEN Feng-hua,MA Jian-min,WANG Ning-li,WANG Jin-jin
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  350-352 . 
    Abstract ( 1739 )   PDF (654KB) ( 2022 )   Save
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    Objective〓〖WTBZ〗To culture the human Tenon′s capsule fibroblast cells in vitro and to observe its growth property. 〖WTHZ〗Methods〓〖WTBZ〗Human tenon′s capsule fibroblast cells were grown in DMEM medium containing 10% fetal bovine serum at 370C, 5%CO2, and the medium was changed every third day. Cell proliferation was assayed by counting the cell number and the cell growth curve was drawn. 〖WTHZ〗Results〓〖WTBZ〗Results revealed that from 48 hours to 7 days after seeding the plate, the cells were in the logarithm growth period. The cells were negatively stained with Cytokeratin and positively with Vimentin. 〖WTHZ〗Conclusion〓〖WTBZ〗Human Tenon′s capsule fibroblast cells are easy to culture and are convenient for cell research in vitro.

    Hydro-dissection combined with nucleus rotation in the capsular bag for posterior capsular opacification

    HU Hai-peng,ZHANG Xiu-ping,SHAO Tie-jun,REN Gui-fang,LUAN Hong

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  353-355 . 
    Abstract ( 1396 )   PDF (234KB) ( 943 )   Save
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    Objective〓〖WTBZ〗To investigate the inhibitive effect of hydro-dissection combined with nucleus rotation in the capsular bag on posterior capsular opacification (PCO) in cataract surgeries. 〖WTHZ〗Methods〓〖WTBZ〗124 eyes were treated with hydrodissection combined with nucleus rotation(group A) and 116 eyes with only hydrodissection (group B) after phacoemulsification with IOL implantation from August 2003 to September 2006. Followed up from 12 to 30 months, differences in incidence and quantification of PCO and incidence of Nd:YAG laser capsulotomy between the two groups were compared. 〖WTHZ〗Results〓〖WTBZ〗PCO incidence rate in groups A and B respectively was 8.06% and 20.69%. Nd:YAG laser capsulotomy was performed in 2.42% and 8.62% of groups A and B. 〖WTHZ〗Conclusion〓〖WTBZ〗Hydrodissection combined with nucleus rotation in the capsular bag is effective in inhibiting PCO after cataract surgeries.

    Phacoemulsification in treatment of secondary glaucoma due to intumescent cataract in 34 cases
    SI Yan-fang,GUAN Juan,ZHOU Li,SHENG Yu,ZHAO Hui-ying
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  356-358 . 
    Abstract ( 1546 )   PDF (267KB) ( 1546 )   Save
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    Objective〓〖WTBZ〗To explore the clinical effect of phacoemulsification with foldable lens implantation through a clear corneal incision in treatment of secondary glaucoma due to intumescent cataract. 〖WTHZ〗Methods〓〖WTBZ〗The clinical data of 34 cases (41 eyes) of secondary glaucoma due to intumescent cataract admitted to our hospital from June 2003 to March 2007 were retrospectively analyzed. Of them, 34 eyes whose intraocular pressure (IOP) was controlled by drugs underwent delayed phacoemulsifications with foldable IOL implantations through clear corneal incisions, and 7 eyes whose high IOP was not controlled underwent emergent operations. The IOP, best corrected eye vision (BCVA), depth of the anterior chamber (AC) and width of the AC were determined before and after the operations. Patients were followed up from 2 months to 3 years. [WTHZ]Results〓〖WTBZ〗All patients were successfully operated on without severe complications, the mean BCVA was significantly increased after the operations,[0.40±0.21 vs 0.15±0.09(P<0 01)], the mean IOP was significantly decreased after the operations [(14.2±4.03)mmHg vs (32.36±6.83)mmHg (P<0.01)], the depth of AC significantly increased after the operations [(2.48±0.37)mm vs (1.14±0.38)mm (P<0.01)], and the angles of AC became wider after the operations. 2 eyes were given anti-glaucoma drugs to decrease the IOP six months after the operations. 〖WTHZ〗Conclusion〓〖WTBZ〗Phacoemulsification with foldable lens implantation through a clear corneal incision is an effective means for secondary glaucoma due to intumescent cataract.

    Ultrasound biomicroscopy in angle-closure glaucoma surgery
    WANG Jian-rong,ZHANG Chen-ming,LIU Wei,LI Ying-mei,WEI Ning
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  359-361 . 
    Abstract ( 2063 )   PDF (248KB) ( 1642 )   Save
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    Objective〓〖WTBZ〗To investigate the value of ultrasound bio-microscopy (UBM) before and after angle-closure glaucoma surgeries. 〖WTHZ〗Methods〓〖WTBZ〗The clinical data of 740 cases (963 eyes)of angle closure glaucoma which were performed UBM from 2004 to 2007 were retrospectively analyzed. 〖WTHZ〗Results〓〖WTBZ〗All patients were clearly diagnosed and rationally operated on. The intraocular pressure was decreased in all patients. Also the post-operative evaluation is timely and reasonable. 〖WTHZ〗Conclusion〓〖WTBZ〗UBM plays an important role in angleclosure glaucoma surgery.

    Vitreo-retinal surgery for severe ocular trauma in 52 cases

    DONG Wei-hong,BI Hong-sheng,WANG Xing-rong,MA Xian-zhen,DU Xiu-juan,YU Chao

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  362-365 . 
    Abstract ( 1451 )   PDF (276KB) ( 1291 )   Save
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    Objective〓〖WTBZ〗To explore the effect of vitreo-retinal surgery for severe ocular trauma. 〖WTHZ〗Methods〓〖WTBZ〗52 patients (52 eyes) with severe ocular trauma were treated with vitreo-retinal surgeries from July 2005 to September 2007 in our hospital. Followed up from 6 to 24 months, the retina and eyesight were observed. 〖WTHZ〗Results〓〖WTBZ〗All were successfully operated on. Retinas were completed attached in 48 eyes(92.31%) and partially attached in 3 eyes. Visual acuity was improved in 41 eyes (78.85%) in different degrees and reached 0.1 or better in 27 eyes (51.92%). The best visual acuity was 1.0. 〖WTHZ〗Conclusion〓〖WTBZ〗Vitreo-retinal surgery is an effective method for severe ocular traumas, and with it severely injured eyes can be effectively saved and visual acuity can be improved.

    Triamcinolone acetonide combined with micro-pulse diode laser in treatment of diabetic macular edema

    LU Ai-dong,LIU Xiao-ling,GAO Jie,CHEN Fang,LIANG Zhong-qi

    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  366-368 . 
    Abstract ( 1954 )   PDF (275KB) ( 1485 )   Save
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    Objective〓〖WTBZ〗To explore the therapeutic effect and security of triamcinolone acetonide combined with micro-pulse diode laser for diabetic macular edema.〖WTHZ〗Methods〓〖WTBZ〗36 patients (40 eyes) with diabetic macular edema were treated with an intra-vitreous injection of 0.1mL(4?mg) triamcinolone acetonide after fundus fluorescein angiography(FFA) by a micro-pulse diode laser. During 3 months follow-up,the visual acuity, intraocular pressure, inflammation in the anterior chamber, FFA and optical coherence tomography were determined. 〖WTHZ〗Results〓〖WTBZ〗The visions of all the patients was improved in varying degrees, and it was improved from 0.1 to 0.5 in one patient suffering from the disease for 3 years. High intraoular pressure occurred in 3 patients and was controlled by eye-drops in 2 patients and by additional oral medicine in 1. Pseudo-ophthalmia happened in 1 patient. Macular edema was relieved in all patients. 〖WTHZ〗Conclusion〓〖WTBZ〗Triamcinolone acetonide combined with micro-pulse diode laser is effective and safe for diabetic macular edema.

    Relationships among different refractive components following penetrating keratoplasty
    WANG Xiang-ru,JIANG Hua,ZHANG Xia,WANG Xiao-li
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  373-375 . 
    Abstract ( 1376 )   PDF (247KB) ( 997 )   Save
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    Objective〓〖WTBZ〗To explore the relationships among different refractive components following penetrating keratoplasty(PKP) and to evaluate the refractive changes induced by PKP. 〖WTHZ〗Methods〓〖WTBZ〗32 New Zealand white rabbits were divided into groups A, B, C and D. The diameter of the adopt hole was 7.0mm in each group, but the donor diameter was 7.0mm, 7.25mm, 7.5mm and 8.0mm in groups A, B, C and D. The differences of donor button and host bed(Δd), corneal dioptric power, corneal thickness, anterior chamber depth and lense thickness were supposedas cause quantity X1, X2, X3, X4 and X5, and the axial length served as the result quantity. All the refractive components were examined before the operations and 1 week, 2 weeks, 1 month, 2 months and 3 months after the operations. Mathematic models of regression equations were built. 〖WTHZ〗Results〓〖WTBZ〗Before the operations, no statistical differences of the refractive components were found in the four groups. After the operations, the mathematic models of regression equations were built as follows: 3 month after the operations: Y=15.238+0.199X1+
    0.5
    44X2-0.060X3+0.129X4-0.094X5. 〖WTHZ〗Conclusion〓〖WTBZ〗Different sizes of donor button and host bed (Δd) can induce changes of refractive components during PKP. The established mathematic model of regression equations is helpful in quantifying the refractive error and controlling the refraction of PKP.

    Trans-scleral suture fixation in implantation of foldable intraocular lenses

    MA Bao-feng,DANG Guang-fu
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  376-378 . 
    Abstract ( 1445 )   PDF (245KB) ( 1328 )   Save
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    Objective〓〖WTBZ〗To explore the clinical effects of trans-scleral suture fixation in foldable intraocular lens implantation in eyes without complete posterior lens capsule supports. 〖WTHZ〗Methods〓〖WTBZ〗16 cases (17 eyes) were treated with trans-scleral ciliary sulcus fixation of foldable intraocular lenses. The operative methods, surgical results and complications were analyzed. 〖WTHZ〗Results〓〖WTBZ〗Followed up from 6 to 30 months, no serious intra-operative complications occurred, and the best corrected visual acuity was improved. Intraocular lenses were dislocated in 2 cases. 〖WTHZ〗Conclusion〓〖WTBZ〗Ciliary sulcus fixation of the foldable intraocular lenses is a safe and effective method in eyes without complete posterior lens capsule supports.

    Changes of the AC/A ratio in school-age children with low myopia

    YUAN Zhong-fang,MU Guo-ying
    JOURNAL OF SHANDONG UNIVERSITY (OTOLARYNGOLOGY AND OPHTHALMOLOGY). 2008, 22(4):  379-380 . 
    Abstract ( 1866 )   PDF (204KB) ( 1696 )   Save
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    Objective〓〖WTBZ〗To explore the correlation between low myopia and accommodative convergence(AC) in school-age children. 〖WTHZ〗Methods〓〖WTBZ〗The AC/A ratio was measured by a Synoptophore in 63 pupils aging from 8 to 12 years. 〖WTHZ〗Result〓〖WTBZ〗The AC/A ratio had obvious differences between the refractive normal group and the low myopia group. 〖WTHZ〗Conclusion〓〖WTBZ〗The AC/A ratio is lower in refractive normal pupils than in low myopia pupils.