山东大学耳鼻喉眼学报 ›› 2026, Vol. 40 ›› Issue (5): 89-93.doi: 10.6040/j.issn.1673-3770.0.2025.477

• 论著 • 上一篇    

70°鼻内镜在泪前隐窝入路上颌窦内翻性乳头状瘤切除术中的应用

赵紫淇,吕操,龚曼旭,兰忠,马燕,朱秋芬,杨晓红,白忠   

  1. 昆明医科大学第二附属医院 耳鼻咽喉科, 云南 昆明 650101
  • 发布日期:2026-09-07
  • 通讯作者: 吕操. E-mail:kmlc2005@163.com
  • 基金资助:
    昆明医科大学教育教学研究课题(2023-JY-Y-031)

The application of 70° endoscope in the resection of inverted papilloma of the maxillary sinus via the prelacrimal recess approach

ZHAO Ziqi, LYU Cao, GONG Manxu, LAN Zhong, MA Yan, ZHU Qiufen, YANG Xiaohong, BAI Zhong   

  1. Department of Otorhinolaryngology, the Second Affiliated Hospital of Kunming Medical University, Kunming 650101, Yunnan, China
  • Published:2026-09-07

摘要: 目的 探讨70°鼻内镜在泪前隐窝入路(prelacrimal recess approach, PLRA)切除上颌窦内翻性乳头状瘤的作用。 方法 回顾性分析15例鼻内镜下泪前隐窝入路切除上颌窦内翻性乳头状瘤的患者临床资料,术前均行鼻内镜、CT、增强MRI检查,明确病变范围。根据同仁分期,其中2期3例、3期12例。0°鼻内镜下常规扩大开放上颌窦口,70°鼻内镜下看到上颌窦下壁、前壁、后外侧壁有肿瘤,不能全部切除。行泪前隐窝切口,使用70°鼻内镜观察上颌窦各壁,手术彻底切除肿瘤。术后定期随访,观察肿瘤复发及临床症状改善情况。 结果 15例患者均完成手术,随访3~36个月,平均12个月。15例患者术后未见肿瘤复发,鼻阻改善,无鼻出血、头痛、复视、溢泪等临床症状发生,无面部疼痛及异常麻木。 结论 鼻内镜下泪前隐窝入路是切除根基部位于上颌窦前壁、下壁、内侧壁前段内翻性乳头状瘤的首选方式,使用70°鼻内镜可观察到上颌窦各壁,视野宽广,有利于彻底切除肿瘤,减少肿瘤复发,改善临床症状。

关键词: 内翻性乳头状瘤, 上颌窦, 泪前隐窝, 鼻内镜

Abstract: Objective To investigate the efficacy of a 70° endoscope in the resection of maxillary sinus inverted papillomas via the prelacrimal recess approach(PLRA). Methods This retrospective analysis reviewed the clinical data of 15 cases of endoscopic resection of maxillary sinus inverted papillomas via the PLRA. All patients underwent preoperative endoscopic, CT, and contrast-enhanced MRI examinations to determine the extent of the lesions. According to the Tongren staging system, 3 cases were classified as Stage 2 and 12 as Stage 3. Under a 0° endoscope, the maxillary sinus ostium was routinely enlarged and opened; under a 70° endoscope, tumors were observed on the inferior, anterior, and posterolateral wall of the maxillary sinus, and complete resection was not possible. A prelacrimal fossa incision was made, and a 70° endoscope was used to visualize the walls of the maxillary sinus, followed by complete surgical resection of the tumor. Postoperative follow-up was conducted regularly to monitor for tumor recurrence and assess improvement in clinical symptoms. Results All 15 patients underwent the procedure. They were followed up for 3 to 36 months, with a mean follow-up of 12 months. None of the 15 patients experienced tumor recurrence postoperatively; nasal obstruction improved, and no clinical symptoms such as epistaxis, headache, diplopia, or epiphora occurred. There were no reports of facial pain and abnormal numbness. Conclusion The PLRA is the preferred method for resecting inverted papillomas whose base is located on the anterior, inferior, or anterior segment of the medial wall of the maxillary sinus. The use of a 70° endoscope allows for visualization of all walls of the maxillary sinus, providing a wide field of view that facilitates complete tumor resection, reduces the risk of recurrence, and improves clinical symptoms.

Key words: Inverted papilloma, Maxillary sinus, Prelacrimal recess, Nasal endoscopy

中图分类号: 

  • R765.9
[1] Pianelli C, Radici M, Camaioni A, et al. Inverted papilloma. modality of treatment[J]. Acta otorhinolaryngo, 1996, 16(4): 339-346
[2] Zehani A, Chelly I, Marrakchi J, et al. Malignant transformation of nasal inverted papilloma into sarcomatoid carcinoma[J]. TunisieMédicale, 2017, 95(6): 453-454
[3] 张罗, 韩德民, 张盛忠, 等. 鼻腔鼻窦内翻性乳头状瘤[J]. 中国耳鼻咽喉头颈外科, 2008, 15(10): 599-604
[4] 周兵, 韩德民, 崔顺九, 等. 鼻内镜下鼻腔外侧壁切开上颌窦手术[J]. 中华耳鼻咽喉头颈外科杂志, 2007, 42(10): 743-748. DOI:10.3760/j.issn:1673-0860.2007.10.006
[5] 张罗, 王成硕. 鼻腔鼻窦内翻性乳头状瘤的术式选择[J]. 中华耳鼻咽喉头颈外科杂志, 2020, 55(1): 8-13.DOI:10.3760/cma.j.issn.1673-0860.2020.01.003
[6] Yan CH, Tong CCL, Penta M, et al. Imaging predictors for malignant transformation of inverted Papilloma[J]. Laryngoscope, 2019, 129(4): 777-782. DOI:10.1002/lary.27582
[7] Simmen D, Veerasigamani N, Briner HR, et al. Anterior maxillary wall and lacrimal duct relationship-CT analysis for prelacrimal access to the maxillary sinus[J]. Rhin, 2017, 55(2): 170-174. DOI:10.4193/rhino16.318
[8] Maina IW, Tong CCL, Baranov E, et al. Clinical implications of carcinoma in situ in sinonasal inverted Papilloma[J]. Otolaryngol - head Neck Surg, 2019, 161(6): 1036-1042. DOI:10.1177/0194599819883298
[9] Busquets JM, Hwang PH. Endoscopic resection of sinonasal inverted Papilloma: a meta-analysis[J]. Otolaryngol - head Neck Surg, 2006, 134(3): 476-482. DOI:10.1016/j.otohns.2005.11.038
[10] Makihara S, Kariya S, Naito T, et al. Attachment-oriented endoscopic surgical management for inverted papillomas in the nasal cavity and paranasal sinuses[J]. Auris Nasus Larynx, 2019, 46(5): 748-753. DOI:10.1016/j.anl.2019.02.007
[11] Zhou B, Huang Q, Sun JW, et al. Resection of inverted Papilloma of the maxillary sinus via a prelacrimal recess approach: a multicenter retrospective analysis of surgical efficacy[J]. Am J RhinolAllergy, 2018, 32(6): 518-525. DOI:10.1177/1945892418801243
[12] Vinciguerra A, Saccardo T, Verillaud B, et al. Extended endoscopic pre-lacrimal medial maxillectomy to the anterior maxillary sinus wall[J]. Laryngoscope, 2023, 133(11): 2874-2877. DOI:10.1002/lary.30620
[13] Liang N, Huang ZX, Liu HG, et al. Bone involvement: Histopathological evidence for endoscopic management of sinonasal inverted Papilloma[J]. Laryngoscope, 2017, 127(12): 2703-2708. DOI:10.1002/lary.26659
[14] 李峰, 徐明锋, 冯叶开, 等. 泪前隐窝联合鼻中隔临时开窗在复发性鼻内翻性乳头状瘤切除术中的应用体会[J].临床耳鼻咽喉头颈外科杂志, 2023, 37(6): 487-490. DOI:10.13201/j.issn.2096-7993.2023.06.016
[15] Lee JJ, Ahmad Z AM, Kim D, et al. Comparison between endoscopic prelacrimal medial maxillectomy and Caldwell-luc approach for benign maxillary sinus tumors[J]. Clin Exp Otorhinolaryngol, 2019, 12(3): 287-293. DOI:10.21053/ceo.2018.01165
[16] 陆达锴, 汪际云, 张祥宝. 鼻内镜下泪前隐窝入路治疗上颌窦复杂病变的疗效分析[J]. 中国中西医结合耳鼻咽喉科杂志, 2023, 31(2):98-101.DOI:10.16542/j.cnki.issn.1007-4856.2023.02.005
[17] Liang N, Qu J, Huang Q, et al. Prelacrimal recess approach for maxillary sinus inverted Papilloma: a 15-year experience from a single center[J]. Eur Arch Oto Rhino Laryngol, 2024, 281(9): 4763-4771. DOI:10.1007/s00405-024-08551-x
[18] 董怿, 崔顺九, 黄谦, 等. 内镜下泪前隐窝入路手术对鼻腔鼻窦内翻性乳头状瘤的疗效及并发症分析[J]. 中国耳鼻咽喉头颈外科, 2025, 32(4): 229-233. DOI:10.16066/j.1672-7002.2025.04.006
[1] 李帅,黄春燕,常明章. 鼻内镜下鼻中隔软骨尾端偏曲矫正术的临床效果分析[J]. 山东大学耳鼻喉眼学报, 2025, 39(6): 65-70.
[2] 王再兴,唐志元,李定波,石照辉,曾宪海,张秋航. 鼻咽癌放疗后肿瘤复发及颅底骨坏死引起颈内动脉破裂的治疗方案[J]. 山东大学耳鼻喉眼学报, 2025, 39(4): 49-58.
[3] 姜知临,朱瑞楷,邱前辉. 基于影像学对咽旁颈内动脉走行的观察与分析[J]. 山东大学耳鼻喉眼学报, 2025, 39(4): 69-76.
[4] 郭荣昌,刘晴航,王洪增,孙树军. 巨大鼻眼贯通、颅底嵌顿异物损伤1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2025, 39(4): 135-141.
[5] 毕恒,谢佳,龚辉成. p-mTOR、p-S6K在鼻腔鼻窦内翻性乳头状瘤中的高表达及临床价值[J]. 山东大学耳鼻喉眼学报, 2025, 39(2): 25-34.
[6] 李晓宇,王彬晨,徐大朋,王艳华,杜平功,张庆泉. 三维建模配准分析经口与经鼻开窗治疗上颌骨囊肿三维形态变化[J]. 山东大学耳鼻喉眼学报, 2025, 39(2): 72-78.
[7] 孙乐,张云云,刘浩,叶京英,吴彦桥. 鼻内镜辅助下经口鼻联合入路腭部巨大多形性腺瘤切除术1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2025, 39(1): 117-122.
[8] 石忠刚,蔡晓岚,李学忠,张立强,冯昕. 上颌骨囊肿并内翻性乳头状瘤1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2025, 39(1): 123-129.
[9] 侯静,房高丽,周兵. 功能性鼻内镜手术后鼻黏膜囊泡的形成机制及囊液成分分析:一项组织生化学研究[J]. 山东大学耳鼻喉眼学报, 2024, 38(5): 1-5.
[10] 郑露,程杰,欧阳虹,池花明,杜敬东. A型血友病致难治性鼻出血1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2024, 38(5): 86-90.
[11] 李美辰,陈海玲,李阳,马登殿. 下鼻甲黏液囊肿1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2024, 38(5): 91-94.
[12] 后婕,刘丁丁,王涵东,徐峥嵘,钱晓云,高下,俞晨杰. 鼻内镜下经泪前隐窝-翼突入路上咽旁间隙病变手术[J]. 山东大学耳鼻喉眼学报, 2024, 38(4): 28-35.
[13] 陈兴雪,张广玲,武天义,王卫卫,孙占伟,李世超,王广科. 抗IL-4Rα单克隆抗体与鼻内镜手术治疗嗜酸性粒细胞型慢性鼻窦炎伴鼻息肉的疗效分析[J]. 山东大学耳鼻喉眼学报, 2024, 38(4): 43-54.
[14] 袁玥,庞文会,陈敏,付圣尧,于龙刚,孙钰博,李玲玲. 毛霉菌性鼻窦炎25例临床特征分析[J]. 山东大学耳鼻喉眼学报, 2024, 38(4): 102-107.
[15] 李红金,王剑,来育斌,许敏,薛涛,陈福权,查定军,陈晓栋. 不同术式治疗上颌骨囊肿的疗效评价[J]. 山东大学耳鼻喉眼学报, 2024, 38(3): 33-37.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!