关键词: 变应原, 济南, 点刺试验, 变应性鼻炎

Abstract:

Objective   To explore the allergens of allergic rhinitis(AR) patients living in Jinan area. Methods   The medical records of skin prick tests (SPT) performed in 1138 AR patients were retrospectively analyzed. The samples were divided into two groups based on age or on gender: the 2-18-year old group and the 19-70-year old group， or the male group and the female group. Sensitizing allergens were assessed and the positive rates of aeroallergens were compared between the groups. Results   There were 843 patients (74.08%) with positive prick test result. The  aeroallergens was as follows: mite in 745 cases(88.37%), cockroach in 363 cases(43.06%), farina in 301 cases(35.71%), freshwater fish in 207 cases(24.56%), dog hair in 139 cases(16.49%), cat hair in 74 cases(8.78%), scandent hop in 39 cases(4.63%), Felon herb in 18 cases(2.14%), albumen in 15 cases(1.78%), mutton in 12 cases(1.42%), milk in 4 cases(0.43%) and beans in 3 cases(0.36%). There was significant difference of distribution of cockroach and dog hair between the age groups (P<0.01). There was no significant difference between male and female patients neither in distribution of aeroallergens nor in single allergen and multiple allergens(P>0.05).  Conclusion   The most common allergen in patients with allergic rhinitis in Jinan seems to be mite, and the second is cockroach and farina. Mutton, milk and been are rate allergen of allergic rhinitis patients in Jinan. With the age growing, part allergens positive rate are changed. The distribution of aeroallergens has no correlation with gender.

Key words: Allergic rhinitis, Skin prick test, Allergens, Jinan