山东大学耳鼻喉眼学报 ›› 2013, Vol. 27 ›› Issue (6): 53-56.doi: 10.6040/j.issn.1673-3770.0.2013.189

• 论著 • 上一篇    下一篇

腺样体肥大儿童伴变应性鼻炎与分泌性中耳炎的相关性分析

吴佳欐,陈淑梅,田欣,赵利敏,倪坤,顾美珍,陈佳瑞,周佳蕾,李晓艳   

  1. 上海市儿童医院耳鼻咽喉头颈外科, 上海 200040
  • 收稿日期:2013-06-23 发布日期:2013-12-16
  • 作者简介:吴佳欐。 Email:wujiali540@hotmail.com

Relationship between allergic rhinitis and secretory otitis media in children with adenoid hypertrophy

WU Jia-li, CHEN Shu-mei, TIAN Xin, ZHAO Li-min, NI Kun, GU Mei-zhen, CHEN Jia-rui, ZHOU Jia-lei, LI Xiao-yan   

  1. Department of Otolaryngology & Head and Neck Surgery, Shanghai Children′s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200040,China
  • Received:2013-06-23 Published:2013-12-16

摘要:

目的    分析腺样体肥大儿童伴分泌性中耳炎(OME)与变应性鼻炎(AR)发病的相关性。方法    回顾性分析12岁以下870例腺样体肥大患儿的病史,分析AR、咽鼓管功能不良及OME的相关性。结果    本组腺样体肥大患儿中AR发病率为30.11%,AR在不同年龄组中的发病率差异有统计学意义,随着年龄增加,发病率逐渐升高(P<0.01)。6岁以内发生咽鼓管功能障碍及OME的概率高,其中1~3岁组发生分泌性中耳炎的概率最大(P<0.01)。春季OME发病率高(P<0.001)。与不伴AR患者相比,伴有AR患儿患咽鼓管功能不良的概率增加了0.4倍(P=0.042);但患有OME的检出率减少了32%(P=0.0472)。结论    在腺样体肥大患儿中,多种因素使咽鼓管功能不良乃至OME高发。其中咽鼓管及其周围结构生理、病理、发育特点是最主要的因素,变态反应是次要影响因素。随着年龄增长,前者因逐渐发育完善,致病性降低,后者致病性增高,但总的发病率是逐渐降低的。

关键词: 咽鼓管功能障碍, 腺样体肥大, 分泌性中耳炎, 变应性鼻炎

Abstract:

Objective    To investigate the correlation between otitis media with effusion (OME) and allergic rhinitis(AR) in children with adenoid hypertrophy. Methods    870 patients under 12 years old with adenoid hypertrophy were collected for current retrospective analysis. Association between AR and eustachian tube dysfunction and OME was calculated by Chi-square test and logistic regression model. Results        The prevalence of allergic rhinitis children with adenoid hypertrophy was 30.11%. The prevalence of allergic rhinitis in different age groups had significant difference and increased with age(P< 0.01). The probability of eustachian tube dysfunction and OME occurring in patients younger than 6 years was high and reached the highest in 1 to 3 years old patients(P=0.001). OME prevalence was higher in spring(P=0.001) than in other seasons. The prevalence of allergic rhinitis with eustachian tube dysfunction was 1.4 times higher than those without allergic rhinitis(P=0.042). The detection rate of OME with AR was 0.32 times hihger than that of OME without AR(P=0.052). Conclusion    The structures, physiological and pathological characteristics of eustachian tube are the main factors causing eustachian tube dysfunction and high incidence of OME. Allergy maybe the secondary factor. With children′s growth,the pathogenicity of the former becomes lower and the latter becomes higher, but the incidence of otitis media with effusion decreases.

Key words: Otitis media with effusion, Eustachian tube dysfunction, Adenoid hypertrophy, Allergic rhinitis

中图分类号: 

  • R764.21
[1] 吕倩,唐源,顾子君,施赛磊,刘萍,万文锦. 变应性鼻炎患者疾病获益感现状及影响因素分析[J]. 山东大学耳鼻喉眼学报, 2026, 40(1): 21-28.
[2] 顾敏,陆美萍. 纳米药物输送系统在变应性鼻炎过敏原免疫治疗中的应用进展[J]. 山东大学耳鼻喉眼学报, 2026, 40(1): 106-111.
[3] 秦娜娜,李玉芬,孙雨浩,魏健,李钦. 基于TGF-β1/Smad信号通路探讨白细胞介素13受体α2对变应性鼻炎大鼠鼻黏膜组织重塑的影响[J]. 山东大学耳鼻喉眼学报, 2025, 39(6): 71-77.
[4] 熊琴, 张砚, 乌日娜, 李锋, 唐力行. 鼻用糖皮质激素在儿童中的应用[J]. 山东大学耳鼻喉眼学报, 2025, 39(6): 160-167.
[5] 许雪萌,樊磊,喻望博,蒋芝月,潘晨,黄泳芹. 奥马珠单抗联合特异性免疫治疗变应性鼻炎疗效的Meta分析[J]. 山东大学耳鼻喉眼学报, 2025, 39(5): 26-33.
[6] 黄焕,华红利,邓玉琴,江承洋,王雨薇,杨星海. 儿童过敏性鼻炎、扁桃体腺样体肥大和鼻窦炎之间相关性及其对临床指导价值[J]. 山东大学耳鼻喉眼学报, 2025, 39(5): 34-41.
[7] 刘怡君,谷悦,官大宇,杨玉成,沈暘. 翼管神经切断术在难治性变应性鼻炎中远期临床疗效和安全性[J]. 山东大学耳鼻喉眼学报, 2025, 39(5): 42-48.
[8] 张婷,王美兰,高映勤. 白细胞介素35在变应性鼻炎中的研究进展[J]. 山东大学耳鼻喉眼学报, 2025, 39(5): 139-147.
[9] 王尧,陈静怡,杨颖超,苏开明. 先天性纤维蛋白原缺乏症儿童的扁桃体腺样体切除病例分析1例及文献复习[J]. 山东大学耳鼻喉眼学报, 2025, 39(3): 77-80.
[10] 张竹萍,彭孜灿,肖振龙,李程,喻迪,王兴龙,陈伟,郭蓓. 新型鼻分泌物嗜酸粒细胞阳离子蛋白-髓过氧化物酶试纸在变应性鼻炎中的应用价值[J]. 山东大学耳鼻喉眼学报, 2025, 39(3): 129-134.
[11] 刘畅,杨景朴,高雨,王文佳. 长春地区儿童变应性鼻炎变应原检测结果分析[J]. 山东大学耳鼻喉眼学报, 2025, 39(2): 51-58.
[12] 周荷青,申琪. 中医药治疗变应性鼻炎疗效的生物标志物研究进展[J]. 山东大学耳鼻喉眼学报, 2025, 39(2): 168-176.
[13] 王曼娴,郑泉,杨亮. 细菌裂解物治疗变应性鼻炎的研究进展[J]. 山东大学耳鼻喉眼学报, 2025, 39(1): 141-145.
[14] 周莹,王刚,王磊,张晓丽,韩浩伦,李保卫,孙喆喆,吴玮. 咽喉反流相关中耳炎1例并文献复习[J]. 山东大学耳鼻喉眼学报, 2024, 38(6): 131-135.
[15] 刘畅,方宏艳,刘敩,富东娜,王贺,王晶,杨景朴. 长春地区秋季变应性鼻炎蒿属花粉致敏特征分析[J]. 山东大学耳鼻喉眼学报, 2024, 38(5): 13-19.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!