山东大学耳鼻喉眼学报 ›› 2017, Vol. 31 ›› Issue (6): 1-4.doi: 10.6040/j.issn.1673-3770.1.2017.037

• 甲状腺癌的规范化诊断与治疗·专题笔谈 •    下一篇

2017年新版WHO甲状腺交界性肿瘤解读

刘志艳   

  1. 山东大学齐鲁医院病理科, 山东大学基础医学院病理学系, 山东 济南 250012
  • 收稿日期:2017-10-09 出版日期:2017-12-16 发布日期:2017-12-16
  • 通讯作者: 刘志艳. E-mail:zhiyanliu@sdu.edu.cn

Borderline thyroid tumor in the new World Health Organization classification of 2017.

LIU Zhiyan   

  1. Department of Pathology, Qilu Hospital of Shandong University, Department of Pathology, School of Basic Medical Sciences, Shandong University, Jinan 250012, Shandong, China
  • Received:2017-10-09 Online:2017-12-16 Published:2017-12-16

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摘要： 2017年第4版WHO内分泌肿瘤分册对甲状腺肿瘤的分类进行了全面更新,提出了甲状腺交界性肿瘤的概念,进一步完善了甲状腺疾病谱。甲状腺交界性肿瘤包括原透明变梁状肿瘤、形态和生物学行为界于滤泡腺瘤和滤泡癌/滤泡型乳头状癌之间的其他包裹性滤泡性肿瘤。后者根据有可疑包膜和/或脉管浸润或无浸润分成恶性潜能未定的肿瘤和具有乳头状核特点的非浸润性甲状腺滤泡性肿瘤两大类。而恶性潜能未定的肿瘤,进一步根据无/有甲状腺乳头状癌细胞核特点分为恶性潜能未定的高分化肿瘤和恶性潜能未定的滤泡性肿瘤。

关键词: 甲状腺交界性肿瘤, 具有乳头状核特点的非浸润性甲状腺滤泡性肿瘤, 恶性潜能未定的肿瘤

Abstract: The World Health Organization(WHO)classification of endocrine tumors was published on June 26, 2017. The classification of borderline thyroid tumors was proposed and it increased the spectrum of thyroid diseases, which includes hyalinizing trabecular tumors and other encapsulated, follicular-patterned thyroid tumors that are morphologically and behaviorally indeterminate between follicular adenomas and follicular carcinoma/follicular-variant papillary thyroid carcinomas. The latter was further classified into tumors of uncertain malignant potential and non-invasive follicular thyroid neoplasms with papillary-like nuclear features, according to whether questionable capsular and/or vascular invasion are present. Tumors of uncertain malignant potential were further divided into well-differentiated tumors with uncertain malignant potential and follicular tumors of uncertain malignant potential according to whether papillary thyroid carcinoma-type nuclear features are present.

Key words: Tumour of uncertain malignant potential, Non-invasive follicular thyroid neoplasm with papillary-like nuclear features, Borderline thyroid tumour

中图分类号: 

  • R736.1
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