山东大学耳鼻喉眼学报

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低温等离子射频治疗阻塞性睡眠呼吸暂停低通气综合征60例

刘洪军,张爱芬,李 娜,刘爱芹   

  1. 潍坊医学院第三附属医院耳鼻咽喉科, 山东 青州 262500
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-10-24 发布日期:2007-10-24
  • 通讯作者: 刘洪军

Effect of plasma radio-frequency at a low temperature for 60 patients with obstructive sleep apnea hypopnea syndrome

LIU Hong-jun, ZHANG Ai-fen, LINa, LIU Ai-qin   

  1. Department of Otorhinolarynglogy, Third Affiliated Hospital of Weifang Medical College, Qingzhou 262500, Shandong, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-10-24 Published:2007-10-24
  • Contact: LIU Hong-jun

摘要: 目的 探讨低温等离子射频减容(RFA)治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的临床方法和疗效。方法 采用ENTecCobatorTM手术系统治疗仪和 一次性Reflex45、Reflex55刀头,对60例OSAHS患者肥厚的下鼻甲、软腭、悬雍垂、咽侧索及舌根等进行黏膜下打孔减容手术(RFA)。术中根据患者的阻塞部位不同而采取不同的手术方法,变应性鼻炎患者并行抗过敏治疗。手术均在局麻下进行。结果 所有患者术中、术后无明显并发症发生。手术后6个月、12个月呼吸暂停低通气指数(AHI)最低血氧饱和度(LSaO2)指标均明显改善(P<0.01),手术后软腭、舌根部体积较术前明显缩小,咽腔扩大,症状明显减轻 或消失,呼吸暂停次数明显减少,白天嗜睡消失或基本消失,精力充沛。按照OSAHS诊断依据和疗效评定标准,6个月后治愈18例,显效28例,有效10例,无效4例,总有效率为93.33%;12个月后治愈15例,显效25例,有效13例,无效7例,总有效率为88.33%;轻度较中重度有效率高(分别为100%,67.3%)。结论 低温等离子射频减容(RFA)治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)简便、省时、无并发症,患者易接受且可重复治疗,临床疗效确切,值得临床推广,但其远期疗效尚有待观察和探讨。

关键词: 等离子射频减容术, 睡眠呼吸暂停低通气综合征

Abstract: Objective To investigate and study the clinical effect of plasma radiofrequency ablation (RFA) at a low temperature in treatment of obstructive sleep apnea hypopnea syndrome (OSAHS). Methods Infraturbinal, soft palate, uvula and tongue base were channeled using ENTec-CobatorTM plasma surgical instruments,which was made by the Arthrocare Company, USA in all 60 cases. Nocturnal polysomnography(PSG)and fibroptic laryngoscope examination were performed on before and after the operations. Different operations were based on different obstruction planes under local anesthesia: ① only RFA on the infraturbinal, soft palate, uvula and tongue base; ② RFA after tonsillectomy plus partial resection of the soft palate and uvula; ③ gradual RFA after tonsillectomy for the unbearable patients; ④ RFA accompanied with nasal septum deviation and polyps resection under endoscopy. Results Symptoms of all patients were alleviated or vanished: the apnea time was remarkably reduced, all patients were vigorous in the daytime, the free margin of the soft palate was elevated, the uvula was shortened, the volume of the tonsil was remarkably reduced, and the pharyngeal space was significantly expanded. No complications occurred during and after the operations. The mean AHI of OSAHS patients decreased and the mean lowest SaO2 increased after the operations (P<0.01); in general, 18 cases were cured, 28 patients showed an excellent effect, 10 cases showed a good effect and 4 cases had no effect after 6 months, whereas 15, 25, 13, and 7 respectively after 12 months. The effect rate was 93.33%(56/60)and 88.33%(53/60), respectively. Conclusion Plasma radiofrequency ablation (RFA) is an effective method for obstructive sleep apnea hypopnea syndrome (OSAHS) and it is simple, microtraumatic, safe and accessible and can be popularized in clinical work, but its longterm effect is unclear.

Key words: Radio-frequency ablation(RFA), Sleep apneahypopnea syndrome, obstructive

中图分类号: 

  • R766.7
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