Journal of Otolaryngology and Ophthalmology of Shandong University ›› 2019, Vol. 33 ›› Issue (2): 86-89.doi: 10.6040/j.issn.1673-3770.0.2018.252

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Treatment of coexisting obstructive sleep apnea and laryngopharyngeal reflux disease and analysis of its characteristic reflux symptom index and reflux finding score

HU An, XING Yanli, CHEN Xiaoping, XUE Xiaocheng, ZHANG Yi, XU Weihua   

  1. Department of Otorhinolaryngology, Public Hospital of Shanghai Pudong District, Shanghai 200135, China
  • Published:2019-03-28

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Abstract: Objective To analyze the reflux finding score(RFS)and reflux symptom index(RSI)in patients with laryngopharyngeal reflux disease(LPRD)and obstructive sleep apnea syndrome(OSAS)and to observe the clinical treatment effect. Methods Between January 2016 and December 2017, 100 patients with LPRD were selected. Patients with OSAS were included as the observation group(n=39), and the rest were observed as the control group(n=61). The RFS and RSI were assessed in the two groups. The RSI, RFS, apnea-hypopnea index(AHI), blood oxygen saturation(SaO2), total reflux, and total reflux time were compared after 2 months of treatment. Results The total RFS and RSI scores in the observation group were significantly higher than those in the control group. The difference in the signs of RFS was statistically significant(P<0.05). Subglottic edema, disappearance of the laryngeal chamber, anaphylactic erythema/congestion, laryngeal mucosal edema, and the posterior combined hypertrophy or swelling score were significantly higher in the observation group than in the control group(P<0.05). In the RSI, the dyspnea, heartburn, chest pain, acid reflux, and gastric acid reflux scores were significantly higher in the observation group than in the control group(P<0.05). After treatment, the RSI scores in the observation group were higher than those in the control group(P<0.05), but the control group had significantly better dyspnea, heartburn, chest pain, and acid reflux scores than did the observation group(P<0.05). Before and after treatment, the AHI, SaO2, and total reflux of the two groups were significantly different(P<0.05). The AHI and SaO2 of the observation group showed a significant improvement after treatment than before treatment(P<0.05). The total reflux and total reflux time showed significant improvements in both the groups, but the improvement was better in the control group than in the observation group(P<0.05). Conclusion Coexisting OSAS may aggravate the symptoms associated with laryngopharyngeal reflux in patients with LPRD, which may be the cause of poor treatment outcome and symptom improvement in patients with LPRD.

Key words: Laryngopharyngeal reflux, Obstructive sleep apnea syndrome, Reflux finding score, Reflux symptom index

CLC Number: 

  • R766
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