山东大学耳鼻喉眼学报 ›› 2017, Vol. 31 ›› Issue (4): 51-53.doi: 10.6040/j.issn.1673-3770.0.2017.199

• 论著 • 上一篇    下一篇

鼻和咽部原发性非霍奇金淋巴瘤17例临床分析

秦贺,胡斌,叶京英   

  1. 清华大学附属北京清华长庚医院耳鼻咽喉头颈外科, 北京 102218
  • 收稿日期:2017-05-10 出版日期:2017-08-16 发布日期:2017-08-16
  • 通讯作者: 叶京英. E-mail: yejingying@yeah.net

Clinical analysis of 17 patients with primary non-Hodgkins lymphoma in the nose and the pharynx.

QIN He, HU Bin, YE Jingying   

  1. Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing 102218, China
  • Received:2017-05-10 Online:2017-08-16 Published:2017-08-16

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摘要： 目的 总结鼻和咽部原发性非霍奇金淋巴瘤的临床特点,提高及时确诊率。 方法 回顾性分析收治的资料完整并经病理确诊的原发性鼻和咽部非霍奇金淋巴瘤17例的临床资料。 结果 鼻腔和鼻窦非霍奇金淋巴瘤患者首发症状包括鼻塞、流涕、鼻出血和外鼻畸形。鼻咽部非霍奇金淋巴瘤患者表现为耳鸣和听力下降,口咽部非霍奇金淋巴瘤患者表现为咽部异物感、咽痛、吞咽困难等。鼻和咽部原发性非霍奇金淋巴瘤临床表现无特异性,新生物表面有大量坏死组织,对可疑患者需要局麻或全麻下反复活检。 结论 鼻和咽部原发性非霍奇金淋巴瘤临床症状多不典型,易造成误诊、漏诊,及时行病理活检是确诊鼻和咽部原发性非霍奇金淋巴瘤的主要手段。

关键词: 鼻腔, 鼻咽, 非霍奇金淋巴瘤, 口咽

Abstract: Objective To analyze the clinical characteristics of primary non-Hodgkins lymphoma in the nose and pharynx. Methods The clinical data of 17 patients with pathologically confirmed non-Hodgkins lymphoma of the nose and pharynx were retrospectively reviewed. Results Six patients with non-Hodgkins lymphoma in the nasal cavity and paranasal sinuses showed nasal obstruction, nasal discharge, bloody rhinorrhea, malformation of the external nose, or hearing loss. Four patients with nasopharyngeal non-Hodgkins lymphoma presented with tinnitus and hearing loss. Seven patients with non-Hodgkins lymphoma in the oropharynx reported foreign body sensation in the throat, pharyngalgia, and dysphagia. The clinical manifestations of primary non-Hodgkins lymphoma in the nose and pharynx were non-specific. There was a large amount of necrotic tissue covering the surface of the neoplasm. In three patients, a biopsy was performed more than once before non-Hodgkins lymphoma was confirmed. Conclusion Diagnosis of primary non-Hodgkins lymphoma in the nose and pharynx is often missed. An accurate diagnosis is best achieved by pathological biopsy.

Key words: Nasal cavity, Nasopharynx, Oropharynx, Non-Hodgkins lymphoma

中图分类号: 

  • R739.6
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