ISSN 1673-3770 CN 37-1437/R
山东大学耳鼻喉眼学报 ›› 2022, Vol. 37 ›› Issue (6): 33-40.doi: 10.6040/j.issn.1673-3770.0.2022.051
• 名师特稿 • 下一篇
张慧,吕慧霞
ZHANG Hui, LÜ Huixia
摘要： 阻塞性睡眠呼吸暂停(obstructive sleep apnea, OSA)作为心力衰竭(heart failure, HF)的独立危险因子,通过多种复杂的病理生理机制促进心肌重构,与HF预后不良相关。但由于合并OSA的HF患者白天嗜睡的症状并不明显,因此在临床工作中对于HF患者并不常规筛查OSA。此外,尽管持续气道正压通气(continuous positive airway pressure, CPAP)作为治疗OSA的主要方式,可以提高睡眠质量及缓解日间嗜睡症状,但是最新的心衰指南并未明确指出其对合并OSA的HF患者心脏结构功能及预后的影响。因此,论文拟对OSA在HF病情进展中潜在的作用机制及CPAP对合并OSA的HF患者心脏结构功能及预后影响的相关研究现状进行总结,提高临床医师对HF患者合并OSA的重视,推进HF患者中OSA的早期筛查和及时有效的诊治。
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