儿童扁桃体腺样体肥大组织淋巴细胞改变的研究进展

doi:10.6040/j.issn.1673-3770.0.2022.096

摘要/Abstract

摘要： 扁桃体腺样体肥大是儿童阻塞性睡眠呼吸暂停最常见的病因,由于缺乏安全有效的内科学治疗手段,对于其发病机制的探索越来越受到人们的关注。近年来许多国内外的研究表明肥大扁桃体腺样体组织中过度的炎症反应和生发中心反应与淋巴细胞组成和功能的异常相关,论文将对此进行综述。

关键词: 扁桃体腺样体肥大, 阻塞性睡眠呼吸暂停, T细胞, B细胞, 固有淋巴样细胞

Abstract: Adenotonsillar hypertrophy is the most common cause of pediatric obstructive sleep apnea. The immunopathologic findings of adenotonsillar hypertrophy have become a field of interest due to the lack of a safe and effective medical treatment. Recent local and foreign studies have shown that the excessive inflammatory response and germinal center response in hypertrophied adenotonsillar tissue are related to the abnormal composition and function of the lymphocytes. These characteristics will be described further in this review.

Key words: Adenotonsillar hypertrophy, Obstructive Sleep apnea, T cells, B cells, Innate lymphoid cells

中图分类号:

R766.3

朱雅欣,刘峰,关建,殷善开. 儿童扁桃体腺样体肥大组织淋巴细胞改变的研究进展[J]. 山东大学耳鼻喉眼学报, 2023, 37(6): 62-67.

ZHU Yaxin,LIU Feng,GUAN Jian,YIN Shankai. Advances in the changes of lymphocytes in pediatric adenoid and tonsil hypertrophy[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2023, 37(6): 62-67.

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