山东大学耳鼻喉眼学报 ›› 2024, Vol. 38 ›› Issue (4): 36-42.doi: 10.6040/j.issn.1673-3770.0.2023.393

• 论著 • 上一篇    

过敏性鼻炎与儿童新冠病毒肺炎感染及症状的关联性研究

张杰1,2,陈敏1,申征征2,吴宇华2,刘原虎1,孙浩2,谭新华2,倪树仁2,杨书勋2,史雪峥2,倪鑫1   

  1. 1.国家儿童医学中心/首都医科大学附属北京儿童医院 耳鼻咽喉头颈外科, 北京 100045;
    2.北京儿童医院顺义妇儿医院 耳鼻咽喉头颈外科, 北京 101300
  • 发布日期:2024-07-09
  • 通讯作者: 倪鑫. E-mail:nixin@bch.com.cn

Study on the correlation between allergic rhinitis and coronavirus disease-2019 infection and symptoms in children

ZHANG Jie1,2, CHEN Min1, SHEN Zhengzheng2, WU Yuhua2, LIU Yuanhu1, SUN Hao2, TAN Xinhua2, NI Shuren2, YANG Shuxun2, SHI Xuezheng2, NI Xin1   

  1. 1. Department of Otorhinolaryngology & Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China2. Department of Otorhinolaryngology & Head and Neck Surgery, Shunyi Women's & Children's Hospital of Beijing Children's Hospital, Beijing 101300, China
  • Published:2024-07-09

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摘要： 目的 探究过敏性鼻炎对儿童新冠病毒肺炎(corona virus disease 2019, COVID-19)感染的影响。 方法 回顾性分析205例门诊患儿,使用问卷表收集一般情况、过敏性鼻炎、COVID-19感染的临床资料。用视觉模拟评分法对COVID-19感染后各部位症状进行评分。通过比较COVID-19感染组与非感染组在性别、年龄、过敏性鼻炎方面的差异,通过线性回归分析感染组中症状轻重的影响因素。 结果 COVID-19感染与年龄、性别、过敏性鼻炎等因素无关。152例COVID-19感染患儿中,年龄与全身症状、咽喉部症状评分呈正相关。非过敏性患儿与过敏性鼻炎患儿COVID-19感染的症状得分没有统计学差异。 结论 过敏性鼻炎对儿童人群COVID-19感染和症状轻重的影响很小,且对感染后的病程长短几乎没有影响。儿童COVID-19患者在全身症状、咽喉部症状的程度与年龄呈正相关。

关键词: 儿童COVID-19, 过敏性鼻炎, 影响因素, 年龄, 血管紧张素转化酶2

Abstract: Objective This study examined the potential impact of allergic rhinitis on children's susceptibility to and experience of coronavirus disease-2019(COVID-19)infection. Methods A retrospective analysis was conducted on 205 outpatients. Clinical data were collected through a questionnaire that assessed general information, presence of allergic rhinitis, and COVID-19 infection status. A visual analog scale was used to score the severity of COVID-19 symptoms across body areas. Chi-square and non-parametric tests were used to compare the differences in age, sex, and allergic rhinitis prevalence between the COVID-19 infection and non-infection groups. Linear regression analysis explored factors influencing symptom severity in the infection group. Results No significant association was found between COVID-19 infection and age, sex, allergic rhinitis, or other factors. Among the 152 children infected with COVID-19, age showed a positive correlation between symptom scores between children with and without allergic rhinitis. Conclusion In children, allergic rhinitis appears to have minimal impact on COVID-19 infection susceptibility, symptoms severity, or disease duration. While age demonstrated a positive correlation to the severity of throat symptoms in children with COVID-19, allergic rhinitis status was not a significant factor.

Key words: Pediatric COVID-19, Allergic rhinitis, Influencing factors, Age, Angiotensin converting enzyme 2

中图分类号: 

  • R765.21
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