山东大学耳鼻喉眼学报 ›› 2020, Vol. 34 ›› Issue (5): 97-101.doi: 10.6040/j.issn.1673-3770.1.2020.082

• 研究进展 • 上一篇    下一篇

3D-FLAIR MRI在内耳出血所致的SSNHL诊断中的作用

赵欢娣1,成颖1综述杨军2,张青1,2审校   

  1. 赵欢娣1, 成颖1 综述杨军2, 张青1, 2 审校1. 西安交通大学第二附属医院 耳鼻咽喉头颈外科, 陕西 西安 710004;
    2. 上海交通大学医学院附属新华医院 耳鼻咽喉头颈外科/上海交通大学医学院耳科学研究所/上海市耳鼻疾病转化医学重点实验室, 上海 200092
  • 收稿日期:2020-08-09 发布日期:2020-11-17
  • 基金资助:
    国家自然科学基金(81670945,81970891);陕西省国际科技合作重点项目(2020KWZ-019);陕西省重点研发项目(2018SF-189)

The role of three-dimensional fluid attenuated inversion recovery magnetic resonance imaging in diagnosis of sudden sensorineural hearing loss caused by inner ear hemorrhage

  • Received:2020-08-09 Published:2020-11-17

摘要: 突发性感音神经性听力下降(SSNHL),是指72 h内突发,原因不明的感音神经性听力损失,至少在相邻三个频率的听力下降≥30 dB HL,其中一个可能的病因就是内耳出血;然而,常规MRI序列仍很难发现内耳出血。现有研究表明3D-FLAIR MRI序列有可能敏感地发现SSNHL患者中的内耳出血。综述了临床上应用3D-FLAIR MRI序列评价内耳出血所致SSNHL的相关研究。

关键词: 内耳出血, 核磁共振成像, 3D-FLAIR序列, 内耳高信号, 听力丧失, 眩晕

Abstract: Sudden sensorineural hearing loss(SSNHL)is defined as a decease in hearing ≥30 dB HL affecting at least three consecutive frequencies with no identifiable cause within 72 h. A possible cause is inner ear hemorrhage. However, detecting inner ear hemorrhage is difficult with conventional magnetic resonance imaging(MRI)sequences. Some studies showed that the 3-dimensional fluid attenuated inversion recovery(3D-FLAIR)MRI sequence could sensitively detect inner ear hemorrhage in SSNHL patients. In this article, we review the related literature about the clinical application of the 3D-FLAIR MRI sequence to evaluate SSNHL caused by inner ear hemorrhage.

Key words: Inner ear hemorrhage, Magnetic resonance imaging, 3D-FLAIR sequence, High signal in inner ear, Hearing loss, Vertigo

中图分类号: 

  • R764
[1] Chandrasekhar SS, Tsai Do BS, Schwartz SR, et al. Clinical practice guideline: sudden hearing loss(update)[J]. Otolaryngol Head Neck Surg, 2019, 161(1_suppl): S1-S45. doi:10.1177/0194599819859885.
[2] Chau JK, Lin JR, Atashband S, et al. Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss[J]. Laryngoscope, 2010, 120(5): 1011-1021. doi:10.1002/lary.20873.
[3] Kothari M, Knopp E, Jonas S, et al. Presumed vestibular hemorrhage secondary to warfarin[J]. Neuroradiology, 1995, 37(4): 324-325. doi:10.1007/BF00588347.
[4] Salomone R, Abu TAA, Chaves AG, et al. Sudden hearing loss caused by labyrinthine hemorrhage[J]. Braz J Otorhinolaryngol, 2008, 74(5): 776-779. doi:10.1016/S1808-8694(15)31390-2.
[5] Sugiura M, Naganawa S, Teranishi M, et al. Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings in patients with sudden sensorineural hearing loss[J]. Laryngoscope, 2006, 116(8): 1451-1454. doi:10.1097/01.mlg.0000228005.78187.23.
[6] Yoshida T, Sugiura M, Naganawa S, et al. Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings and prognosis in sudden sensorineural hearing loss[J]. Laryngoscope, 2008, 118(8): 1433-1437. doi:10.1097/MLG.0b013e318172ef85.
[7] Kallmes DF, Hui FK, Mugler JP. Suppression of cerebrospinal fluid and blood flow artifacts in FLAIR MR imaging with a single-slab three-dimensional pulse sequence: initial experience[J]. Radiology, 2001, 221(1): 251-255. doi:10.1148/radiol.2211001712.
[8] Naganawa S, Koshikawa T, Nakamura T, et al. Comparison of flow artifacts between 2D-FLAIR and 3D-FLAIR sequences at 3 T[J]. Eur Radiol, 2004, 14(10): 1901-1908. doi:10.1007/s00330-004-2372-7.
[9] Naganawa S, Nakashima T. Cutting edge of inner ear MRI[J]. Acta Otolaryngol Suppl, 2009(560): 15-21. doi:10.1080/00016480902729819.
[10] Naganawa S. The technical and clinical features of 3D-FLAIR in neuroimaging[J]. Magn Reson Med Sci, 2015, 14(2): 93-106. doi:10.2463/mrms.2014-0132.
[11] Ryu IS, Yoon TH, Ahn JH, et al. Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging in sudden sensorineural hearing loss: correlations with audiologic and vestibular testing[J]. Otol Neurotol, 2011, 32(8): 1205-1209. doi:10.1097/MAO.0b013e31822e969f.
[12] Gao Z, Chi FL. The clinical value of three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging in patients with idiopathic sudden sensorineural hearing loss: a meta-analysis[J]. Otol Neurotol, 2014, 35(10): 1730-1735. doi:10.1097/mao.0000000000000611.
[13] Wu X, Chen KT, Sun L, et al. Magnetic resonance imaging-detected inner ear hemorrhage as a potential cause of sudden sensorineural hearing loss[J]. Am J Otolaryngol, 2014, 35(3): 318-323. doi:10.1016/j.amjoto.2014.02.004.
[14] Lee JI, Yoon RG, Lee JH, et al. Prognostic value of labyrinthine 3D-FLAIR abnormalities in idiopathic sudden sensorineural hearing loss[J]. AJNR Am J Neuroradiol, 2016, 37(12): 2317-2322. doi:10.3174/ajnr.A4901.
[15] Lee JW, Park YA, Park SM, et al. Clinical features and prognosis of sudden sensorineural hearing loss secondary to intralabyrinthine hemorrhage[J]. J Audiol Otol, 2016, 20(1): 31-35. doi:10.7874/jao.2016.20.1.31.
[16] Kim DS, Park DW, Kim TY, et al. Characteristic MR findings suggesting presumed labyrinthine hemorrhage[J]. Acta Otolaryngol, 2017, 137(12): 1226-1232. doi:10.1080/00016489.2017.1363911.
[17] Lammers MJW, Young E, Fenton D, et al. The prognostic value and pathophysiologic significance of three-dimensional fluid-attenuated inversion recovery(3D-FLAIR)magnetic resonance imaging in idiopathic sudden sensorineural hearing loss: a systematic review and meta-analysis[J]. Clin Otolaryngol, 2019, 44(6): 1017-1025. doi:10.1111/coa.13432.
[18] Lee HY, Jung SY, Park MS, et al. Feasibility of three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging as a prognostic factor in patients with sudden hearing loss[J]. Eur Arch Otorhinolaryngol, 2012, 269(8): 1885-1891. doi:10.1007/s00405-011-1834-1.
[19] Berrettini S, Seccia V, Fortunato S, et al. Analysis of the 3-dimensional fluid-attenuated inversion-recovery(3D-FLAIR)sequence in idiopathic sudden sensorineural hearing loss[J]. JAMA Otolaryngol Head Neck Surg, 2013, 139(5): 456-464. doi:10.1001/jamaoto.2013.2659.
[20] Liao WH, Wu HM, Wu HY, et al. Revisiting the relationship of three-dimensional fluid attenuation inversion recovery imaging and hearing outcomes in adults with idiopathic unilateral sudden sensorineural hearing loss[J]. Eur J Radiol, 2016, 85(12): 2188-2194. doi:10.1016/j.ejrad.2016.10.005.
[21] Chen XH, Zeng CJ, Fang ZM, et al. The natural history of labyrinthine hemorrhage in patients with sudden sensorineural hearing loss[J]. Ear Nose Throat J, 2019, 98(5): E13-E20. doi:10.1177/0145561319834862.
[22] Naganawa S, Komada T, Fukatsu H, et al. Observation of contrast enhancement in the cochlear fluid space of healthy subjects using a 3D-FLAIR sequence at 3 Tesla[J]. Eur Radiol, 2006, 16(3): 733-737. doi:10.1007/s00330-005-0046-8.
[23] Tanigawa T, Shibata R, Tanaka H, et al. Usefulness of three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging to detect inner-ear abnormalities in patients with sudden sensorineural hearing loss[J]. J Laryngol Otol, 2015, 129(1): 11-15. doi:10.1017/S0022215114003028.
[24] Naganawa S, Kawai H, Sone M, et al. Increased sensitivity to low concentration gadolinium contrast by optimized heavily T2-weighted 3D-FLAIR to visualize endolymphatic space[J]. Magn Reson Med Sci, 2010, 9(2): 73-80. doi:10.2463/mrms.9.73.
[25] Naganawa S, Kawai H, Taoka T, et al. Heavily T2-weighted 3D-FLAIR improves the detection of cochlear lymph fluid signal abnormalities in patients with sudden sensorineural hearing loss[J]. Magn Reson Med Sci, 2016, 15(2): 203-211. doi:10.2463/mrms.mp.2015-0065.
[1] 许嘉, 李欣, 陈雯婧, 高娟娟, 卢星星, 伊海金. 联合应用内淋巴囊减压和局部激素治疗难治性梅尼埃病的短期与长期疗效分析[J]. 山东大学耳鼻喉眼学报, 2022, 36(4): 17-21.
[2] 张瑶瑶,王海涛. 内耳钆造影磁共振成像技术在梅尼埃病诊疗中的应用[J]. 山东大学耳鼻喉眼学报, 2021, 35(6): 101-107.
[3] 蒋黎娜,于倩如,于杰,关本岭,鹿玉,于淑东. 前庭性眩晕疾病患者焦虑和抑郁状况研究[J]. 山东大学耳鼻喉眼学报, 2020, 34(6): 1-5.
[4] 杨军,郑贵亮. 外周前庭疾病的诊断和治疗[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 1-6.
[5] 刘宇鹏,梁敏,何景春,郑贵亮,李姝娜,张青,杨军. 梅尼埃病前庭功能分级的探讨[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 14-19.
[6] 刘宇鹏,吴文瑾,何景春,郑贵亮,张青,杨军. 迷路后径路前庭神经切断术治疗难治性梅尼埃病75例[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 46-50.
[7] 陈建勇, 孙夏雨, 沈佳丽, 汪玮, 王璐, 贺宽, 张勤, 马孝宝, 沈敏, 陈向平, 杨军. 原发性良性阵发性位置性眩晕患者VEMP异常率的临床观察[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 51-55.
[8] 邓巧媚,王巍,温超,刘强,毛翔,韩曦,李姗姗,陈太生,徐开旭,林鹏. 头晕眩晕与眼震强度的关系研究[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 56-60.
[9] 郑贵亮, 刘凌峰, 陈建勇, 张青, 杨军. 基于移动互联网的前庭康复训练指导平台的开发与应用[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 78-81.
[10] 魏馨雨,杨方园杨军,张青. 耳源性细菌性迷路炎研究进展[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 102-107.
[11] 王玥, 上官翰京 蔡成福. 睡眠对良性阵发性位置性眩晕影响的研究进展[J]. 山东大学耳鼻喉眼学报, 2020, 34(5): 108-112.
[12] 伊海金,杨仕明. 重视耳部外伤诊疗工作[J]. 山东大学耳鼻喉眼学报, 2020, 34(1): 1-3.
[13] 许嘉,伊海金. 正确处理颞骨骨折耳科并发症[J]. 山东大学耳鼻喉眼学报, 2020, 34(1): 4-8.
[14] 陈太生, 王巍, 徐开旭, 林鹏. 良性阵发性位置性眩晕及其诊断治疗的思考[J]. 山东大学耳鼻喉眼学报, 2019, 33(5): 1-5.
[15] 谢慧. 眩晕的中医认识[J]. 山东大学耳鼻喉眼学报, 2019, 33(5): 11-17.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] 张晗,黄一飞 . 抗角膜移植排斥的研究进展[J]. 山东大学耳鼻喉眼学报, 2006, 20(1): 84 -87 .
[2] 牛善利,柴茂文,李振秀 . 鼻内镜下鼻甲成形术治疗慢性肥厚性鼻炎60例[J]. 山东大学耳鼻喉眼学报, 2006, 20(1): 16 -18 .
[3] 孟庆国,卢永田,范献良 . 杀伤细胞免疫球蛋白样受体基因多态性与鼻咽癌的关联性[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 196 -199 .
[4] 马玉起,孔祥春 . 先天性双侧下唇窦道1例[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 199 -199 .
[5] 万俐佳,鲁海涛,姜义道,刘 辉,李 琴,佘腊枝 . 改良腭咽成形术治疗阻塞性睡眠呼吸暂停综合征41例[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 204 -205 .
[6] 于青青 ,王跃建 . 硬质耳内镜的临床应用进展[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 222 -224 .
[7] 吉晓滨,邓家德,臧林泉,王 磊,谢 军 . 豚鼠变应性鼻炎模型血清组胺的测定[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 228 -230 .
[8] 向登,卢永田,孙焕吉 . 鼻内镜下修补脑脊液鼻漏19例并文献复习[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 234 -236 .
[9] 邱恩惠,李志春,方文旭 . 嗅觉障碍的中西医治疗[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 253 -257 .
[10] 殷国华,钟 笑 . 激光减容术治疗舌扁桃体肥大的远期疗效[J]. 山东大学耳鼻喉眼学报, 2008, 22(3): 280 -282 .