山东大学耳鼻喉眼学报 ›› 2021, Vol. 35 ›› Issue (1): 77-81.doi: 10.6040/j.issn.1673-3770.0.2020.188

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婴幼儿先天性基底型脑膜脑膨出的诊断及鼻内镜手术治疗

陈坤,李磊,孟国珍,杨军,侯东明   

  1. 上海交通大学医学院附属新华医院 耳鼻咽喉头颈外科, 上海 200092
  • 发布日期:2021-02-01
  • 基金资助:
    上海交通大学科技创新专项资金多学科交叉项目(ZH2018ZDA11)

Diagnosis and nasal endoscopic surgery of congenital basal meningoencephaloceles in infants

CHEN Kun, LI Lei, MENG Guozhen, YANG Jun, HOU Dongming   

  1. Department of Otolaryngology & Head and Neck Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
  • Published:2021-02-01

摘要: 目的 探讨婴幼儿先天性基底型脑膜脑膨出的诊断及鼻内镜手术治疗的安全性和有效性。 方法 回顾性分析8例婴幼儿先天性基底型脑膜脑膨出的临床资料。术前进行鼻窦CT和MRI检查,全部病例经鼻内镜下脑膜脑膨出切除术及颅底修复重建术,术后随访手术疗效。 结果 8例病例包括经筛型6例、蝶咽型2例。手术均一次性成功,无并发症出现。术后随访6~74个月未见复发。 结论 对于持续性鼻塞、鼻溢伴有鼻腔或鼻咽部新生物的婴幼儿,应考虑先天性基底型脑膜脑膨出的可能。鼻窦CT及MRI检查具有重要的诊断意义。鼻内镜下膨出物切除术及颅底修复重建术是一种安全、有效的手术方式,并且具有良好的临床效果。

关键词: 先天性脑膜脑膨出, 婴幼儿, 鼻内镜手术, 颅骨缺损, 颅底修复

Abstract: Objective The aim of this study is to investigate the diagnosis of congenital basal meningoencephalocele in infants and the safety and effectiveness of nasal endoscopic surgery. Method A retrospective analysis of the clinical data of 8 cases of congenital basal meningoencephalocele in infants admitted at the Xinhua Hospital affiliated with Shanghai Jiaotong University School of Medicine between April 2014 and December 2019 was conducted. Preoperative sinus CT and MRI examinations were performed, and all cases underwent endoscopic meningoencephalocele resection and skull base reconstruction. Results Six patients presented with transethmoidal meningoencephalocele and 2 transsphenoidal meningoencephaloceles. The operation was successful at one time without complications. There were no recurrences after 6~74 months of follow-up. Conclusion For infants with persistent nasal obstruction and nasal overflow with neoplasms in the nasal cavity or nasopharynx, the possibility of congenital basal meningoencephalocele should be considered. Sinus CT and MRI examinations have important diagnostic significance. Nasal endoscopic resection of the bulge and reconstruction of the skull base is a safe and effective operation and has a good clinical effect.

Key words: Congenital meningoencephalocele, Infant, Nasal endoscopic surgery, Skull defect, Skull base repair

中图分类号: 

  • R714
[1] Wu XW, Zhang JY, Zhang H, et al. Endoscopic surgery for congenital basal meningoencephaloceles in children[J]. Acta Oto - Laryngol, 2016, 136(6): 613-619. doi:10.3109/00016489.2015.1133930.
[2] Tabaee A, Anand VK, Cappabianca P, et al. Endoscopic management of spontaneous meningoencephalocele of the lateral sphenoid sinus[J]. J Neurosurg, 2010, 112(5): 1070-1077. doi:10.3171/2009.7.jns0842.
[3] Jeyaraj P. Management of the frontoethmoidal encephalomeningocele[J]. Ann Maxillofac Surg, 2018, 8(1): 56. doi:10.4103/ams.ams_11_18.
[4] Okano S, Tanaka R, Okayama A, et al. Congenital basal meningoceles with different outcomes: a case series[J]. J Med Case Rep, 2017, 11: 359. doi:10.1186/s13256-017-1497-7.
[5] 杨小健, 张杰, 唐力行, 等. 婴幼儿先天性基底型脑膜脑膨出的诊断与治疗[J]. 中国耳鼻咽喉头颈外科, 2017, 24(3): 128-131. doi:10.16066/j.1672-7002.2017.03.005. YANG Xiaojian, ZHANG Jie, TANG Lixing, et al. Diagnosis and treatment of congenital basal encephaloceles in infants[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2017, 24(3): 128-131. doi:10.16066/j.1672-7002.2017.03.005.
[6] Adil E, Robson C, Perez-Atayde A, et al. Congenital nasal neuroglial heterotopia and encephaloceles: an update on current evaluation and management[J]. Laryngoscope, 2016, 126(9): 2161-2167. doi:10.1002/lary.25864.
[7] 姚红兵. 先天性脑膜脑膨出[J]. 中国医学文摘(耳鼻咽喉科学), 2013, 28(1): 33-34. doi:10.19617/j.issn1001-1307.2013.01.013.
[8] 王军民, 陈海兵, 陈曦, 等. 鼻内镜下自体材料脑脊液鼻漏修补术(附16例临床分析)[J]. 山东大学耳鼻喉眼学报, 2016, 30(6): 37-41, 48. doi:10.6040/j.issn.1673-3770.0.2016.377. WANG Junmin, CHEN Haibing, CHEN Xi, et al. Transnasal endoscopic repair of cerebrospinal fluid rhinorrhea: a clinical analysis of 16 cases[J]. Journal of Otolaryngology and Ophthalmology of Shandong University, 2016, 30(6): 37-41, 48. doi:10.6040/j.issn.1673-3770.0.2016.377.
[9] Keshri A, Shah S, Patadia S, et al. Transnasal endoscopic repair of pediatric meningoencephalocele[J]. J Pediatr Neurosci, 2016, 11(1): 42. doi:10.4103/1817-1745.181249.
[10] 许庚, 李源, 谢民强, 等. 经鼻内镜手术治疗鼻部脑膜脑膨出[J]. 中华耳鼻咽喉科杂志, 2003, 38(1): 47-49. doi:10.3760/j.issn:1673-0860.2003.01.015. XU Geng, LI Yuan, XIE Minqiang, et al. Treatment of endonasal-encephalomeningocele by transnasal endoscopic surgery[J]. Chinese Journal of Otorhinolaryngology, 2003, 38(1): 47-49. doi:10.3760/j.issn:1673-0860.2003.01.015. doi:10.6040/j.issn.1673-3770.0.2020.374.
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